<?xml version="1.0" encoding="UTF-8"?><rss xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:atom="http://www.w3.org/2005/Atom" version="2.0"><channel><title><![CDATA[Literature Review]]></title><description><![CDATA[Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.]]></description><link>https://bioenergetic.forum/category/16</link><generator>RSS for Node</generator><lastBuildDate>Sat, 08 Aug 2026 10:48:10 GMT</lastBuildDate><atom:link href="https://bioenergetic.forum/category/16.rss" rel="self" type="application/rss+xml"/><pubDate>Fri, 24 Jul 2026 06:06:00 GMT</pubDate><ttl>60</ttl><item><title><![CDATA[Statins damage muscles by increasing endotoxin&#x2F;LPS absorption and inhibiting glucose metabolism]]></title><description><![CDATA[@Ena Re: antifungal/antimicrobial effect of lovastatin. It looks like lovastatin (LOV) potentiates other antifungals rather than having that effect by itself.
"LOV single treatment was unable to inhibit C. albicans strains except the ERG3 and ERG11 double mutant. LOV and  itraconazole (ITZ) combination was capable of inhibiting the C. albicans planktonic cells and biofilms synergistically including the ITZ resistant mutants."
--- From the abstract to
Lovastatin synergizes with itraconazole against planktonic cells and biofilms of Candida albicans through the regulation on ergosterol biosynthesis pathway.
]]></description><link>https://bioenergetic.forum/topic/9470/statins-damage-muscles-by-increasing-endotoxin-lps-absorption-and-inhibiting-glucose-metabolism</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9470/statins-damage-muscles-by-increasing-endotoxin-lps-absorption-and-inhibiting-glucose-metabolism</guid><dc:creator><![CDATA[Lejeboca]]></dc:creator><pubDate>Fri, 24 Jul 2026 06:06:00 GMT</pubDate></item><item><title><![CDATA[Intact thymus (a sign of lower cortisol&#x2F;estrogen exposure) is a very good predictor of health&#x2F;longevity]]></title><link>https://bioenergetic.forum/topic/9469/intact-thymus-a-sign-of-lower-cortisol-estrogen-exposure-is-a-very-good-predictor-of-health-longevity</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9469/intact-thymus-a-sign-of-lower-cortisol-estrogen-exposure-is-a-very-good-predictor-of-health-longevity</guid><pubDate>Fri, 24 Jul 2026 01:20:00 GMT</pubDate></item><item><title><![CDATA[Interfering with mitochondrial dynamics causes cancer (by driving inflammation); no carcinogen&#x2F;mutation required!]]></title><description><![CDATA[@haidut
I am wondering if it is really inflammation that is causing mitochondrial dysfunction and not the other way around.
I have a large store of bacteria that I keep having to kill and each time there is a kill plenty of endotoxins are released and they are a major source of inflammation. And it suppresses mitochondrial activity to the point that even the conversion of cholesterol to pregnenolone and downstream prosuction of hormones and steroids are very much affected.
To such effect that taking hormones like thyroid and pregnenolone and progesterone can hardly make a dent.
I had to inhibit the nfkb inflammatory response using turmeric and black pepper in order to see my cholesterol level go down and my hormonal production go up.
But it is hard to keep endotoxins low when there is a large colony of pathogenic microbes and in my case it is feom periodontal infection having translocated to my vascular and lymphatic system where it get more embedded over time especially as it gets protected by biofilms.
One way I see out of this conundrum of killing pathogens by relying on our endogenous ROS from our own innate immune system and from use of pharma antibiotics or herbal antibacterials,, which all end up producing endotoxins; is to engage antibacterial peptides such  as LL-37 in neutrophils and macrophages - to kill pathogens with the benefit of not leaving behind endotoxins that both inflame and cause oxidative stress.
More sunshine to produce high levels of Vitamin D (50-80 ng/dl) together with plenty of butyric acid in the gut gives the body a high endogenous supply of LL-37 to achieve effective antimicrobial activity without endotoxic side effects.
]]></description><link>https://bioenergetic.forum/topic/9468/interfering-with-mitochondrial-dynamics-causes-cancer-by-driving-inflammation-no-carcinogen-mutation-required</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9468/interfering-with-mitochondrial-dynamics-causes-cancer-by-driving-inflammation-no-carcinogen-mutation-required</guid><dc:creator><![CDATA[yerrag]]></dc:creator><pubDate>Thu, 23 Jul 2026 22:47:00 GMT</pubDate></item><item><title><![CDATA[Excessive fatty acid oxidation (FAO) drives heart failure by depleting cardiolipin]]></title><link>https://bioenergetic.forum/topic/9467/excessive-fatty-acid-oxidation-fao-drives-heart-failure-by-depleting-cardiolipin</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9467/excessive-fatty-acid-oxidation-fao-drives-heart-failure-by-depleting-cardiolipin</guid><pubDate>Thu, 23 Jul 2026 17:47:00 GMT</pubDate></item><item><title><![CDATA[Blocking the endotoxin&#x2F;LPS receptor (TLR4) prevents brain damage from concussion]]></title><link>https://bioenergetic.forum/topic/9466/blocking-the-endotoxin-lps-receptor-tlr4-prevents-brain-damage-from-concussion</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9466/blocking-the-endotoxin-lps-receptor-tlr4-prevents-brain-damage-from-concussion</guid><pubDate>Thu, 23 Jul 2026 17:29:00 GMT</pubDate></item><item><title><![CDATA[Eliminating sugar (sucrose) from the diet leads to diabetes, as well as gut and liver inflammation]]></title><link>https://bioenergetic.forum/topic/9465/eliminating-sugar-sucrose-from-the-diet-leads-to-diabetes-as-well-as-gut-and-liver-inflammation</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9465/eliminating-sugar-sucrose-from-the-diet-leads-to-diabetes-as-well-as-gut-and-liver-inflammation</guid><pubDate>Thu, 23 Jul 2026 07:18:00 GMT</pubDate></item><item><title><![CDATA[Estrogen drives thyroid cancer in women]]></title><link>https://bioenergetic.forum/topic/9464/estrogen-drives-thyroid-cancer-in-women</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9464/estrogen-drives-thyroid-cancer-in-women</guid><pubDate>Thu, 23 Jul 2026 06:41:01 GMT</pubDate></item><item><title><![CDATA[Increase lactate production is what drives the decline of NAD+ seen in aging and disease]]></title><link>https://bioenergetic.forum/topic/9463/increase-lactate-production-is-what-drives-the-decline-of-nad-seen-in-aging-and-disease</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9463/increase-lactate-production-is-what-drives-the-decline-of-nad-seen-in-aging-and-disease</guid><pubDate>Thu, 23 Jul 2026 06:30:00 GMT</pubDate></item><item><title><![CDATA[Higher progesterone&#x2F;estrogen ratio may help extinguish traumatic memories (e.g. PTSD)]]></title><link>https://bioenergetic.forum/topic/9462/higher-progesterone-estrogen-ratio-may-help-extinguish-traumatic-memories-e.g.-ptsd</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9462/higher-progesterone-estrogen-ratio-may-help-extinguish-traumatic-memories-e.g.-ptsd</guid><pubDate>Thu, 23 Jul 2026 03:27:00 GMT</pubDate></item><item><title><![CDATA[Popular weight loss drugs (GLP-1 agonists) kill libido by activating a serotonin receptor (5-HT2C)]]></title><link>https://bioenergetic.forum/topic/9461/popular-weight-loss-drugs-glp-1-agonists-kill-libido-by-activating-a-serotonin-receptor-5-ht2c</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9461/popular-weight-loss-drugs-glp-1-agonists-kill-libido-by-activating-a-serotonin-receptor-5-ht2c</guid><pubDate>Thu, 23 Jul 2026 03:13:02 GMT</pubDate></item><item><title><![CDATA[Restoring phosphatidylcholine levels through supplementation reverses (mitochondrial) aging]]></title><description><![CDATA[So then, Mitolipin to the rescue
]]></description><link>https://bioenergetic.forum/topic/9459/restoring-phosphatidylcholine-levels-through-supplementation-reverses-mitochondrial-aging</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9459/restoring-phosphatidylcholine-levels-through-supplementation-reverses-mitochondrial-aging</guid><dc:creator><![CDATA[bio3nergetic]]></dc:creator><pubDate>Thu, 23 Jul 2026 02:48:00 GMT</pubDate></item><item><title><![CDATA[Ray’s ideas are now being adopted by academia without a single quote&#x2F;reference to his work]]></title><description><![CDATA[There is also morphogenic resonance going on of the Ray Peat ideas thoughts energetic expressions consciousness and all. The more of us talking about these ideas working towards pro metabolic higher metabolic lives etc… we are spreading these ideas into the Aether and scientists influencers kids people are getting seeded these ideas and they resonate with them. Resonance, it happens constantly in culture, through marketing magic but also just by morphogenic fields.
I mean people are trending towards rays ideas because they are more or less the right direction of  full spectrum truth. And big brains like Georgi and some of the folks here are broadcasting electron flow awareness out to the universe! Grab a tank of co2 and a glass of milk and tune in!
Plagiarism is constantly an annoying part of life also.
]]></description><link>https://bioenergetic.forum/topic/9458/ray-s-ideas-are-now-being-adopted-by-academia-without-a-single-quote-reference-to-his-work</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9458/ray-s-ideas-are-now-being-adopted-by-academia-without-a-single-quote-reference-to-his-work</guid><dc:creator><![CDATA[dapose]]></dc:creator><pubDate>Thu, 23 Jul 2026 02:36:00 GMT</pubDate></item><item><title><![CDATA[Intranasal niacinamide may reverse lost sense of smell (anosmia) by raising NAD+ levels]]></title><link>https://bioenergetic.forum/topic/9457/intranasal-niacinamide-may-reverse-lost-sense-of-smell-anosmia-by-raising-nad-levels</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9457/intranasal-niacinamide-may-reverse-lost-sense-of-smell-anosmia-by-raising-nad-levels</guid><pubDate>Thu, 23 Jul 2026 02:01:00 GMT</pubDate></item><item><title><![CDATA[Almost 80% of US adults (and ~60% of youth) have at least one chronic condition]]></title><link>https://bioenergetic.forum/topic/9456/almost-80-of-us-adults-and-60-of-youth-have-at-least-one-chronic-condition</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9456/almost-80-of-us-adults-and-60-of-youth-have-at-least-one-chronic-condition</guid><pubDate>Thu, 23 Jul 2026 01:51:00 GMT</pubDate></item><item><title><![CDATA[More than 90% of the aging process is driven by environment, can be reversed; hair graying is a good biomarker of aging]]></title><description><![CDATA[Looks like Picard's work supports the "rate of living theory".
For example, in his
Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging
hypermetabolism, defined as "increased energy expenditure", it is concluded that "a robust and specific temporal association be­tween hypermetabolism and premature cell death, aligning with pro­spective observations in the human literature where hypermetabolism increases mortality risk. Finally, our experimental modulation of OxPhos and total J_ATP suggest that total energy expenditure, rather than flux through mitochondrial OxPhos, may have a particularly influential ef­fect on cellular aging".
Hmm... but the references that they use could be mined further for some gems.
]]></description><link>https://bioenergetic.forum/topic/9455/more-than-90-of-the-aging-process-is-driven-by-environment-can-be-reversed-hair-graying-is-a-good-biomarker-of-aging</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9455/more-than-90-of-the-aging-process-is-driven-by-environment-can-be-reversed-hair-graying-is-a-good-biomarker-of-aging</guid><dc:creator><![CDATA[Lejeboca]]></dc:creator><pubDate>Wed, 22 Jul 2026 21:33:01 GMT</pubDate></item><item><title><![CDATA[Low calcium and vitamin D levels linked to premature hair graying]]></title><link>https://bioenergetic.forum/topic/9454/low-calcium-and-vitamin-d-levels-linked-to-premature-hair-graying</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9454/low-calcium-and-vitamin-d-levels-linked-to-premature-hair-graying</guid><pubDate>Wed, 22 Jul 2026 21:18:00 GMT</pubDate></item><item><title><![CDATA[High-fat diet causes depression by increasing inflammation; low-dose aspirin reverses both]]></title><link>https://bioenergetic.forum/topic/9453/high-fat-diet-causes-depression-by-increasing-inflammation-low-dose-aspirin-reverses-both</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9453/high-fat-diet-causes-depression-by-increasing-inflammation-low-dose-aspirin-reverses-both</guid><pubDate>Wed, 22 Jul 2026 20:38:00 GMT</pubDate></item><item><title><![CDATA[What Does The Tour de France Do To The Human Body?]]></title><description><![CDATA[Damn, talks about broken collarbones and today Vingegaard crashes and likely breaks his.
]]></description><link>https://bioenergetic.forum/topic/9447/what-does-the-tour-de-france-do-to-the-human-body</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9447/what-does-the-tour-de-france-do-to-the-human-body</guid><dc:creator><![CDATA[Luke]]></dc:creator><pubDate>Sat, 18 Jul 2026 01:41:59 GMT</pubDate></item><item><title><![CDATA[tidbits]]></title><description><![CDATA[@sunsunsun Yeah but the point is that the spoons are inaccurate for the exact reason you mentioned XD as well as density etc
]]></description><link>https://bioenergetic.forum/topic/9444/tidbits</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9444/tidbits</guid><dc:creator><![CDATA[alfredoolivas]]></dc:creator><pubDate>Mon, 13 Jul 2026 20:21:10 GMT</pubDate></item><item><title><![CDATA[Essential Fatty Acids (Omega-3 &amp; Omega-6) are direct building blocks for the skin&#x27;s lipid bilayers, reducing transepidermal water loss (TEWL).]]></title><description><![CDATA[What I have to say about the studies on “essential fatty acid deficiency (EFAD)” is that they are all incomplete, and it is necessary to piece the studies together like a puzzle, in addition to seeking out others that may not specifically address EFAD.
1. The overwhelming number of symptoms attributed to EFAD actually stems from the high metabolic rate caused by TEWL, which activates thermogenesis.
If you neutralize TEWL in an EFAD-affected animal by increasing the humidity in the laboratory, it grows and develops normally without any symptoms. In many studies on EFAD, researchers mention “spontaneous recovery”—usually in the summer, lasting for long periods—followed by a worsening of symptoms, which they attribute to the seasons and their fluctuations in humidity.
[image: 1783716841140-c2beaeab-cd4b-4280-893f-15ed7932ef46-image.jpeg]
2- The body is a dissipative system; if you remove n-3/n-6, the body changes the way it handles various processes that previously relied on them. It is a mistake in these studies to remove n-6 while keeping the diet essentially the same.
I’ll give an example using zinc, a deficiency of which causes similar skin symptoms:
[image: 1783716910557-18db4162-345c-48b3-8870-f9e63651d26c-image.jpeg]
This table shows an EFAD (HCO) diet and a non-EFAD (corn oil) diet, and both have versions supplemented with zinc (C-2 and D-2); the key point here is that the protein source is casein (this detail will be important later):
[image: 1783716961668-e9846a0d-82e0-4480-8775-ccff5e0a2872-image.jpeg]
Now, in this table, it's the same thing, but supplemented with egg albumin instead of casein:
[image: 1783717008090-135a94d7-db40-4a08-b637-c8e7375a8dae-image.jpeg]
It can be seen from these two tables that EFAD causes skin problems if:

There is a zinc deficiency
The proteins are casein-based, rather than egg albumin.

I was curious as to why the type of protein would influence the symptoms, so I remembered this:
[image: 1783717055701-1fcf7b00-75a5-49ff-b33f-950b0a9deb48-image.jpeg]
Egg albumin is rich in sulfur-containing amino acids.
[image: 1783778512118-7b99813c-70e6-4d66-8021-ea93b7d1b7e9-image.jpeg]
I considered the possibility of contamination with PUFA, but they also use soy protein, which I think theoretically poses a greater risk:
[image: 1783717093452-c1514880-eaeb-428f-ada3-bac7bcafde56-image.jpeg]
Is it possible that, with enough zinc, they could live indefinitely on an EFAD diet? Who knows... Well, if the problem is humidity, people who live by the beach can easily follow a diet like this and reap the benefits of the EFAD (resistance to endotoxins, inflammation, autoimmune diseases, snake venom, etc.).
And btw, it is possible for a human to live well in EFAD, without skin problems, in a city as well.
[image: 1783718698155-ec41016c-25cb-4832-b2a5-490f5885f41b-image.jpeg]
(not mine)
Thanks to learnmyhelpless at X for reminding me of zinc and EFAD relationship haha
]]></description><link>https://bioenergetic.forum/topic/9438/essential-fatty-acids-omega-3-omega-6-are-direct-building-blocks-for-the-skin-s-lipid-bilayers-reducing-transepidermal-water-loss-tewl-.</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9438/essential-fatty-acids-omega-3-omega-6-are-direct-building-blocks-for-the-skin-s-lipid-bilayers-reducing-transepidermal-water-loss-tewl-.</guid><dc:creator><![CDATA[TexugoDoMel]]></dc:creator><pubDate>Tue, 07 Jul 2026 03:40:57 GMT</pubDate></item><item><title><![CDATA[Popular joint supplement glucosamine linked to faster Alzheimer’s progression]]></title><description><![CDATA[Talk with AI (Claude) to try to understand Crumblecooking’s comment.

Some info to move the Schmilblick forward (to move things along).

Context:
Weak ground: researchers focused on patients diagnosed with either ADRD or mild cognitive impairment (MCI).
A widely used supplement marketed for joint pain relief may be linked to faster progression of Alzheimer's disease, according to new research from the University of Florida.
Researchers found that glucosamine significantly increased the attachment of sugar molecules to proteins within cells. Mice receiving glucosamine also showed worsening deficits in social memory, which is the ability to recognize and remember other individuals.
When scientists chemically reduced this sugar-tagging activity, memory performance improved.
"In the United States, there are about 7 million people living with Alzheimer's and millions more with related dementias such as Lewy body or frontotemporal dementia," said senior author Ramon Sun, Ph.D., director of the Center for Advanced Spatial Biomolecule Research and associate director for innovation of UF's McKnight Brain Institute. "A lot of these people actively take an over-the-counter supplement that could be making their disease progression worse."
Comment from the forumer Crumblecooking:
Add linoleic acid to this—the prostaglandin E₂ precursor—and you then have a powerful yeast➝hyphal transducer—more commonly known as potato chips, bread, and granola bars.
Comment from LucH (me) (not yet posted):
I know we have here a weak ground: already inflamed cells behind BBB by ROS perturb the cohesion, weakening the balance behind BBB: There is inflammation (via ROS) and perturbation in the brain cells as far as the homeostatic balance is concerned:
Detailed explanation:
The blood-brain barrier (BBB) is composed primarily of cerebral microvascular endothelial cells and astrocytes linked by tight junctions (TJs) and adhesion molecules (AMs). This system maintains the homeostatic balance between the brain parenchyma and the extracellular fluid.
=&gt; Not a proof, OK. But more and more studies take this direction...
How to Help a Leaky BBB before it’s too late (usual process for ¾ people above 80ies)
a) Which useful molecules can cross the BBB:

Aspirin (mind the platelet impact)
Caffeine (coffee and tea)
EGCG (green tea)
Resveratrol
Taurine
Vitamin E
Vitamin C
Etc.
See detailed information on reference 2.

b) How to Heal a Leaky Blood-Brain Barrier
Which Supplements Repair the Blood-Brain Barrier?
Several B vitamins support blood-brain barrier health: a vitamin B1 (thiamine) deficiency disrupts the blood-brain barrier, and supplementation can restore it. Vitamins B12, B5, and B9 (folate) can restore the integrity of the blood-brain barrier. (4) Magnesium, as a cofactor in over 300 biochemical processes, affects brain neurotransmitters, enzymes, and hormones. Magnesium L-threonate is often used for its potential brain benefits and may help manage certain brain disorders, such as depression, Alzheimer's disease, and age-related memory loss.
To be continued on the reference 1.
Sources and references

Useful link: Alzheimer's Cognitive Decline and Inflammation (In French but with links in English)
https://mirzoune-ciboulette.forumactif.org/t2067-declin-cognitif-dans-alzheimer-et-inflammation#29882
What can get through the BBB?
https://my.clevelandclinic.org/health/body/24931-blood-brain-barrier-bbb
The list of what can make it through your BBB is extremely lengthy, so here are some examples …
Antocyanins can cross the BBB
Phenolic compounds that cross the blood–brain barrier exert positive health effects as central nervous system antioxidants. 2021 Food &amp; Function. Dafne Velásquez-Jiménez et al.
What supplements repair the blood-brain barrier?
https://thefnc.com/research/nutrients-to-help-repair-your-blood-brain-barrier/#:~:text=B vitamins.,restore blood-brain barrier integrity
Glutamine et cancer
Un lien intéressant :
https://www.julienvenesson.fr/glutamine-cancer/
A natural compound, EGCG from green tea, also shows promise. It counteracts the action of glutamate dehydrogenase, which converts glutamate into α-ketoglutarate, leading to the death of cancer cells.
https://www.julienvenesson.fr/la-quercetine-ameliore-les-effets-du-the-vert-sur-la-sante/
Glutamine is the preferred amino acid of cancer cells, required for their growth. But if you try to limit this intake, the cancer will destroy muscle tissue to obtain it. You can try to ration it, but never eliminate it. Therefore, you limit it, you don't eliminate it.
NB: Whenever I suffer from a weak / a thin layer of stomach mucin, I associate ¼ tsp glutamine and ¼ tsp taurine powder (+ 1.5 g magnesium bisglycinate). Take one hour before bedtime. Always associate both to dampen the possible glutamate pathway.

Question for AI (Claude)
I don’t want a comment or an analyze of my answer but I’d like an explanation for Crumblecooking’s comment:
“Add linoleic acid to this—the prostaglandin E₂ precursor—and you then have a powerful yeast➝hyphal transducer—more commonly known as potato chips, bread, and granola bars.”
=&gt; What is the mechanism? Asparagine becoming nitrosamine?
Short answer for IA (summarized because in French and 2 pages A4 long)
No, not linked to nitrosamine.
Vocabulary: the yeast→hyphal morphological transition.
Hyphal: Adjective derived from “hypha”, describing anything related to this filamentous form.
We have a morphological change from the yeast form (isolated round cell) to the invasive filamentous form.
So, ultra-processed foods rich in omega-6 oils potentiate the pro-Alzheimer's effect of glucosamine via a dual mechanism: local inflammation (PGE₂) + fungal dysbiosis, promoting a compromised intestinal mucosa/BBB. The hyphal transition of Candida increases epithelial permeability, exacerbating precisely the leaky BBB problem you describe (LucH talking with Claude).
LucH said:
Okay, I get it. It's a stimulant on already fragile ground.
IA says:
Exactly.
That's the most accurate wording.
A stimulator—not a primary cause—on an already weakened foundation:
• Compromised BBB
• Chronic low-grade inflammation
• Already disrupted O-GlcNAcylation
Glucosamine + PGE₂ don't initiate the disease; they accelerate what's already underway. That's why the study refers to aggravated progression, not a trigger.
This ties in with your notion of a weak ground from the introduction—the underlying condition precedes it, the stimulator amplifies it.
]]></description><link>https://bioenergetic.forum/topic/9408/popular-joint-supplement-glucosamine-linked-to-faster-alzheimer-s-progression</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9408/popular-joint-supplement-glucosamine-linked-to-faster-alzheimer-s-progression</guid><dc:creator><![CDATA[LucH]]></dc:creator><pubDate>Fri, 12 Jun 2026 03:03:23 GMT</pubDate></item><item><title><![CDATA[Actionable Steps Website]]></title><link>https://bioenergetic.forum/topic/9404/actionable-steps-website</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9404/actionable-steps-website</guid><pubDate>Sat, 06 Jun 2026 01:53:58 GMT</pubDate></item><item><title><![CDATA[Advanced Glycation End-Products (AGEs) in Coffee]]></title><description><![CDATA[
@AlphaZance said:
Metabolic stress drives the formation of AGEs, but Ray Peat has not addressed existing AGEs in foods.

yes, but you didn't find the right doc. The etymology of the word glycation doesn't only rely on sugar.
You d' better take care of "lipid glycation" and not only from sugar sources.
Request for IA:
glycation doesn't only rely on sugar but much more on fat alteration.
Google answer:
You are on the right track! While sugar drives classic glycation, fat alteration (lipoxidation) is a massive, often underappreciated driver of Advanced Glycation End-products (AGEs).
The Lipid-AGE ConnectionLipoxidation: When fats oxidize, they create reactive, unstable molecules (like dicarbonyls). These intermediate compounds then cross-link with proteins just as sugar molecules do, directly forming harmful AGEs.The Maillard Reaction: Heat processing (such as frying or grilling) animal foods high in both fat and protein yields the highest levels of dietary AGEs.
The Interplay: Both pathways are deeply connected under "carbonyl stress".
How to Manage Both Sugar and Fat Risks
To minimize the buildup of AGEs and slow down cellular aging, you can focus on a few evidence-backed lifestyle and dietary strategies:
Watch Your Cooking Methods: Avoid cooking foods—especially meats and fats—at high temperatures. Steaming, boiling, or poaching creates significantly fewer AGEs than frying, broiling, or grilling.
Balance Dietary Fats: The type of fat you eat matters. Clinical trials suggest that increasing consumption of monounsaturated fats (MUFAs) and Omega-3 fatty acids can help control and beneficially affect your glycation markers.
Maintain Stable Blood Sugar: Even though fat oxidation is crucial, reducing refined sugar and fructose intake lowers the available "fuel" for traditional sugar-protein glycation.Leverage
Antioxidants: Oxidative stress is the catalyst for fat alteration. Consuming antioxidant-rich foods or using targeted anti-glycation interventions helps neutralize free radicals.
Scientific Sources &amp; Evidence
To dive deeper into the science of how fats and sugars alter your cells and skin, review these authoritative resources: [1, 2]

https://www.lifeextension.com/wellness/aging/glycation
https://www.skinnutritioninstitute.com/blog/glycation-how-fat-ages-your-skin-and-destroys-collagen-clone


Glycation &amp; Oxidation: Explore the exact breakdown of how lipid damage forms AGEs through Advanced Glycation End-products (AGEs): an emerging ... - PMC. [1]
https://pmc.ncbi.nlm.nih.gov/articles/PMC4648888/&amp;ved=2ahUKEwjPyLaG4-iUAxXlkP0HHRf_BQEQy_kOegoIAggACAEIJxAC&amp;opi=89978449&amp;cd&amp;psig=AOvVaw2nBJNpgaZPrk0yj1bOffN0&amp;ust=1780497191863000
Lipoxidation Pathways: Read about how both carbohydrates and lipids drive carbonyl stress at Glycation, oxidation, and lipoxidation in the development of ...
Ibidem
Cellular &amp; Skin Impact: Understand how these molecular processes affect your skin's health and elasticity in Sugar is altering your skin in ways no anti-ageing serum can ...
Ibidem

]]></description><link>https://bioenergetic.forum/topic/9400/advanced-glycation-end-products-ages-in-coffee</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9400/advanced-glycation-end-products-ages-in-coffee</guid><dc:creator><![CDATA[LucH]]></dc:creator><pubDate>Tue, 02 Jun 2026 02:44:48 GMT</pubDate></item><item><title><![CDATA[Feeling good on low protein]]></title><description><![CDATA[@sunsunsun Yeah, I personally haven't noticed a drop in strength though, despite losing 19lbs, but that is probably because I take tren. Though in all fairness, very little.
]]></description><link>https://bioenergetic.forum/topic/9399/feeling-good-on-low-protein</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9399/feeling-good-on-low-protein</guid><dc:creator><![CDATA[alfredoolivas]]></dc:creator><pubDate>Mon, 01 Jun 2026 13:24:30 GMT</pubDate></item><item><title><![CDATA[Dinkov Distilled: Metabolic Theory of Health]]></title><description><![CDATA[@springsnow check DMs
]]></description><link>https://bioenergetic.forum/topic/9392/dinkov-distilled-metabolic-theory-of-health</link><guid isPermaLink="true">https://bioenergetic.forum/topic/9392/dinkov-distilled-metabolic-theory-of-health</guid><dc:creator><![CDATA[alfredoolivas]]></dc:creator><pubDate>Tue, 26 May 2026 10:44:09 GMT</pubDate></item></channel></rss>