Childhood trauma alters generations of mice.
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Parents' emotional trauma may change their children's biology. Studies in mice show how
Mansuy and others think stress may influence sncRNAs, along with the many other biochemical changes it causes, from higher levels of hormones like cortisol to inflammation. They have focused on the sncRNAs in sperm, which may be especially vulnerable to stress during the weeks that newly formed sperm spend maturing in a twisting tube on top of the testes. Later, when sperm and egg come together, altered sncRNAs could modify the production of proteins at the very beginning of development in a way that ripples through the millions and millions of cell divisions that follow. "Hosts of signals happen as those cells become a zygote," says epigeneticist Tracy Bale at the University of Maryland in Baltimore. "If dad brings small noncoding RNAs that have an effect on mom's RNAs, that can change the trajectory of embryo development."
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Study finds PTSD effects may linger in body chemistry of next generation
https://www.youtube.com/watch?v=zV9sya4F5KQ
New research on survivors of the Holocaust shows how catastrophic events can alter our body chemistry, and how these changes can transmit to the next generation. The result? Our children may suffer the effects of a traumatic event they never witnessed. -
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