Post in thread 'Ray Peat Email Advice Depository'
https://lowtoxinforum.com/threads/ray-peat-email-advice-depository.1035/post-875276

Q: Thank you Dr.Peat
One more question

You talked about the negative effects of darkness.
So, I was wondering. If someone is a night owl and he spends his night time with a good incandescent light turned on, drinking and eating some sugary stuff, calcium, sodium etc - would the negative effects of darkness be diminished in any way?

RP: Yes, even intermittent bright light can reduce the damage.

A basic protective factor is bio-identical progesterone (not the prescription progestins).

After trying a lot of basic approaches if you still have issues consider looking into the book by Jack Dreyfus "A Remarkable Medicine Has Been Overlooked". He had uncontrollable fear, worries, excessive uncontrollable thoughts, depression. He resolved it by taking an old antiepileptic drug called Dilantin. It is relatively Peaty.

Do not worry too much about developing schizophrenia or "going crazy". Do you have anhedonia?

@Meursault said in Psychosis/Schizophrenia:

You said you take T4, do you feel anything on it?

Not really, I've been taking it for 10~ years, I've tried multiple times to get prescribed T3 but my doctor won't allow it stating that TSH of 2.5 is normal

@16characterstwas said in Psychosis/Schizophrenia:

Vitamin d(3), cypro, b6 (brewers’ yeast) or taurine (seafood) might help with psychosis

Thanks, I'll give cypro and b6 a try

Vitamin d(3), cypro, b6 (brewers’ yeast) or taurine (seafood) might help with psychosis

https://lowtoxinforum.com/search/2633447/?q=Psychosis&c[title_only]=1&c[users]=Haidut&o=date

@randomname said in Psychosis/Schizophrenia:

Is there a way to reverse or prevent further neuron degeneration

fix stress as priority. excitotoxic cell death will only occur when neurons are strained. Your cortisol is high. until you sort this and the SIBO out you are playing a hide and seek game with what foods you are 'sensitive' to IMO. intestinal inflammation/ SIBO will also be increasing cortisol and stress response. look into how to fix that. try glycine and spoonful of sugar at night to prevent crash. cyproheptadine will help histamine and cortisol. you need to eat properly to stop reliance on cortisol. you will crash after breakfast because blood glucose is lowest when you wake up. if you're hypothyroid it will be hard to maintain stable blood sugar. You said you take T4, do you feel anything on it?

@randomname said in Psychosis/Schizophrenia:

What would you recommend I eat or avoid?

just focus on eating enough food at regular times and not crashing. If you have celiac disease and SIBO idk what to advise in terms of specifics.

@randomname said in Psychosis/Schizophrenia:

I’m currently taking:
Aspirin 500 mg – every other day
Creatine 5 g – in the morning

Why?

@randomname said in Psychosis/Schizophrenia:

-What's your opinion on the Abram Hoffer protocol?

I've not heard of this but avoid high doses of B vitamins until more stable. they will increase energy demand and if you're hypothyroid this will just make you crash more.

Can you be more specific please.

I'm constantly changing the diet cause I'm not sure what causes my symptoms to increase
For example yesterday I ate:
Breakfast: Coffee with raw cacao powder and cream + scrambled eggs with cheese + sliced carrot
Lunch: Stake + rice
Evening: OJ and banana
Dinner: Stake + potatoes

@Meursault said in Psychosis/Schizophrenia:

It sounds like you are in an elevated stress state.

100%

@Meursault said in Psychosis/Schizophrenia:

If you are running into problems during sleep, this would suggest to me you are likely running out of glucose during the night, which I'm guessing could be triggering these episodes you mention.

This makes a lot of sense. Those episodes of shakiness mostly happened when I was taking nicotinic acid, and I read it lowers blood glucose.

@Meursault said in Psychosis/Schizophrenia:

How much do you eat every day?

Very little. I have to force myself to eat because I’m not hungry for most of the day. I get most of my hunger in the evening.

@Meursault said in Psychosis/Schizophrenia:

Blood sugar spikes/ crashes?

I notice a crash after breakfast. I also digest most food poorly and usually evacuate about an hour after eating.
The worst symptoms happened when I ate gluten by mistake — seems like I have a really strong gut-brain connection or an impaired blood-brain barrier.
Coffee or milk (haven’t figured out which one yet) also seems to exacerbate my symptoms

Here is my bloodwork from a couple of months ago:
Cortisol: 24.5 µg/dL
25 OH (Vitamin D): 56.5 ng/mL (I had taken 100,000 IU of vitamin D3)
TSH: 2.64 mUI/L
Prolactin: 6.7 ng/mL
Total Testosterone: 7.5 ng/mL
Free Testosterone: 157.4 pg/mL
Insulin: 7.5 µUI/mL
HOMA-IR: 1.65
Glycemia: 89 mg/dL
Red Blood Cell Count: 5,260,000 /mm³
Eosinophils: 11% → Confirmed eosinophilia
(This is always elevated in my bloodwork; doctors usually say it’s due to allergies.)

A couple of questions if you don't mind answering:
-What would you recommend I eat or avoid? (Or could you walk me through what you eat in a day?) Including supplements.
I’m currently taking:
Aspirin 500 mg – every other day
Creatine 5 g – in the morning
Magnesium bisglycinate 40 mg + L-theanine 150 mg – at night
-Is there a way to reverse or prevent further neuron degeneration?
-What's your opinion on the Abram Hoffer protocol?

Side note I live 2 floors above a 5g tower - though I will be moving soon
Thanks

Hallucinations, sleep issues, episodes lasting 20-30 minutes, destroyed mental clarity, lack of short term memory.
These weed strains can trigger a cascade of issues. Who knows what they are sprayed/ treated with.

It sounds like you are in an elevated stress state. If you are in a state of chronically elevated cortisol, you will become more sensitive to serotonin and also dopamine. When your neurons are in stress mode, they become reliant on glutamate for energy, an excitatory neurotransmitter, and without proper inhibition this will cause degeneration. It is the excitatory inhibitors, GABA, Orexin, that will oppose this over-excitatory response, but in a elevated stress state they will not be adequately expressed. Without the relevant action of these inhibitors, glutamate overload will result in excitotoxic cell death, excess serotonin and dopamine will be unopposed.
So it is my theory that when you have these constantly elevated levels of excitatory substances, dopamine, 5ht, glutamate, and you eventually run out of energy to oppose them, it causes these episodes where your brain becomes overloaded with serotonin and dopamine which causes the psychosis type symptoms. For me this went from 30 minutes episodes occasionally to extended periods daily. I would become non-functional, extremely confused, eventually started having hallucinations. As I put myself in a state of chronic stress from starvation.

What is important is to provide yourself with the necessary energy when you are in a sensitive state.
If you are running into problems during sleep, this would suggest to me you are likely running out of glucose during the night, which I'm guessing could be triggering these episodes you mention.
How much do you eat every day?
Do you experience issues after eating?
Blood sugar spikes/ crashes?
If you are hypothyroid, this will be exacerbating wasteful energy and lack of blood sugar regulation, again not providing brain needed energy. Intestinal inflammation will increase serotonin and histamine release.

chronic stress leading to increased seretonin and dopamine in schizophrenics
increased dopamine level in schizophrenia and psychosis
Hope this helps in some way.

Can you be more specific please.

Thanks.

Yeah I'm not sure, I forgot the most important piece of information and it is that I'm experiencing paranoia, disorganized thoughts, I'm irritated by any sound or visual stimulus, it's really hard for me to concentrate in one thing without my mind jumping into another unrelated subject, I have a constant feeling of impending doom, short term memory problems (sometimes I forget things that I did one moment ago). All of that indicates me that I might be developing schizophrenia given that there's a 20-50% change of doing so after a first weed-induced psychotic episode

@randomname said in Psychosis/Schizophrenia:

Please avoid negative comments — i'm struggling a lot with negative thoughts

Help us out.

You'll be alright.

Yeah I'm not sure, I forgot the most important piece of information and it is that I'm experiencing paranoia, disorganized thoughts, I'm irritated by any sound or visual stimulus, it's really hard for me to concentrate in one thing without my mind jumping into another unrelated subject, I have a constant feeling of impending doom, short term memory problems (sometimes I forget things that I did one moment ago). All of that indicates me that I might be developing schizophrenia given that there's a 20-50% change of doing so after a first weed-induced psychotic episode

I’m constantly bloated and have long struggled with immune issues — including asthma and severe dermatitis, which at one point required immunosuppressants.

Maybe you'll come out on a better top.

Current Diet:
Lactose-free milk
Homemade gluten-free bread
Butter
Red meat
Rice
Carrots
Tomatoes
Bananas
Some orange juicejuice

Can you be more specific please.

Should I continue taking nicotinic acid, or is there a safer form of Vitamin B3?

Niacinamide but I don't think you should take anything concentrated for now.