tb500 is barely studied compared to tb4 and people perpetuate the naming mixup

bpc is active orally for systemic issues

small doses of various peptides incl bpc have been shown to work in animals when given frequently .

wa la

its 2026 and theres literally no reason to gatekeep these sources with private messages and secret chats

the ghk cu information on dosing by peptide enthusiasts is a testament to something or other about people because lorne pickharts work on it establishing doses is published in journals , its not secret information. the peptide mixes are just stuff someone made up, the doses make no sense but i guess it saves 8 seconds not having to draw from multiple vials

Would also be interesting whether "normal" GHK-Cu doses supplemented by more oral copper would already enhance its effects.
Someone was spamming all over reddit that the rate-limiting building block for mitochondrial biogenesis could be methyl groups. I doubt that. Obviously some amounts of phospholipids will be necessary. Beyond that perhaps it will require (supraphysiological) provisions of copper for it to reach there and make a therapeutic difference in contrast to the gradual, organic growth and development of tissues before adulthood. Most of the c. 100mg total body Cu may be localized within mitochondria if one does the math of Cu/mtProtein dry mass, with very little in the cytosol, serum and ECM.

@Lordallmighty said:

Like we learnt with BPC, people were running 200mcg 15 years ago and now we know the MG doses are needed

Haven't read about that anywhere either. AFAIK injected BPC plateaus at 500-1000mcg.

"Mass Calculation: Therefore, in a 5 mg total sample of GHK-Cu, the amount of copper corresponds to about 15-16% of that total mass."

"A 5 mg vial of GHK-Cu contains exactly 0.79 mg of pure copper."

Thats almost nothing. so its very surpricing people get so good results even with a dose as 5mg wich some feel is high, and just run 2-3mg

So in a 20mg dose

"A 20 mg vial of GHK-Cu contains exactly 3.15 mg of pure copper"

I personally notice zero collagen effects on 2mg oral copper, but on 4 i do. so having 3.15mg injected from a 20mg ghk cu dose that should def be superior to the 2-3mg ghk cu. So im not super surpriced that he had great effects

But as you said he was also using the kpv/tb500 glow stack wich all increase collagen, but my point is that a high dose copper should really do the work

Not saying that this dose is a must as so many people run low dose with good results, its just very interesting that he felt a super high dose + the other peps gave him so great results. as we still dont know wich dose of all of these therapies are the most effective

I would not be surpriced if it turns out we are microdosing alot of these therapies. Like we learnt with BPC, people were running 200mcg 15 years ago and now we know the MG doses are needed

Tb500 was given in 50mg+ dosing IV for heart faliure for example (dont quote me on the dose but its around there, if not double) yet people can skip surgery by using 1mg every other day

Okey yes i belive it. I notice the anti inflammatory effect right away post injection. Copper also seem to be involved in regulating histamine (chronic pain, wich mcas cause RA btw), people with mcas are copper deficiant, but also vita D deficiant as that also control histamine the most.

It also increase oxygen n dopamine alot, its one of the most effective therapies ive used for mental health. Dont know if i can say the 5mg vs 10mg effect is any different when it comes to the mental effects

Just remembered there are studies on GHK as well, by itself, and it show basically the same results, as ghk bind to the copper thats already in your body n takes it were it needs to go. but as copper is so important the ghk cu must be superior

There is a doc doing podcast rounds right now explaining how copper toxticity is acually copper deficiancy. That we got to much un-bound toxic copper in tissue. I get estrogen issues with oral copper, just like females that got copper IUD, to much copper increase estrogen

But somehow it dident happen with injections, some even see reduced serum copper levels with ghk cu. makes me wounder about the copper toxticity/deficiancy thing

@Lordallmighty said:

https://imgur.com/Rj1pBxx

Those are mad doses with no tangible evidence behind anything at all. It's also all fixed-ratio GLOW.

I had once delved into the zenith of copper research from the early 70's of the few researchers who had resisted the early-50s shift to everything corticosteroids. I may share it at some point. The baseline was that copper therapy, with its right chelators, is super antiinflammatory against RA and the usual suspects and may even be the actual main mechanism behind acetylsalicylic acid. The GHK-Cu may make sense in that light.

But regarding GLP1 n combinations, i started with 0.5mg retatrutide, after all the blood work reviews became public on social media, reducing cholestrol by 50% and other markers of bad metabolism and weight just falls off after fixing insulin levels - with the same kcal intake

Yes we all know cholestrol is crucial, but the levels rise as a protection on the blood vessles and gets driven up by insulin resistance and chronic inflammation so when fixing it with GLP1 the cholestrol levels get restored as the blood vessles are no longer inflammed

After a few months i kepts seeing people curing chronic inflammatory conditions with Trizepatide (monjaro), weather it was chronic pain, IBS, mast cell n histamine disease

So it really made me interested as i got MCAS myself and wayy to much histamine

Even kept seeing people that have done surgery and had metal implants, still have chronic pain and just one dose of microdose triz each week and the pain was gone

Indicating that Triz is one of the strongest anti inflammatory agents that we seen

So i started combining both, 0.5mg each, months later im up to 3mg of each and the effect on inflammation and water retention/histamine is absolutly insaine

Got rid of most of my fibrotic fat, wich regular fat loss and fat loss agent are immune to, as the fibrotic fat isent metabolically active

Yet GLPs target it

In brazil trizepatide is now a treatment for cellulite. wich no other therapy or treatment touches

After i lost all the fat n fibrotic fat im going down to 0.5-1mg and running it for the rest of my life.

Thymosine alpha 1 10mg kits not 5mg like sold online

I found mots C to work better then SS31 but the common conclusion is that ss31 is suppose to be better, causing long lasting results in the mitochondria but personally i dident feel much

Seems like its 50/50 regarding the best mitochondria peptide, 50% feel incredible on mots C, even just 1-2mg, and feel nothing on SS31, and 50% its the other way around, can run 1-2mg SS31 and feel nothing on mots C

I have no idea why people experience it so differently must be the difference in cell damage/different biology and what the body needs

Alot of missinformation by made up peptide gurus have come out, how you need to run ss31 before mots C and then months later they changed it to you need mots c before and then ss31 and nonsense like that

When in reality peptides work just like AAS - were they carry incredible synergy

The difference in running mots c by itself, or adding low dose NAD+ injections and methylation support so the mots c can acually do its job, its not SS31 that gonna do the groud work, its NAD+ and carnitine, and methylation support as it will be drained otherwise by all the new mitochondria thats being created

You are never suppose to use mito supps without having the raw material as a base. The raw material isent other peptides like ss31 its the basic B vitamins for metabolism, and methylation support

NAD+, mots C, methylene blue, Carnitine injections + red light therapy and PEMF - Combination of the gods

But i kept seeing reddit posts on 10mg dosing and how much better that was vs 5mg

Some seem to get results at 2-3mg, some need 5mg, but it really seem like the higher the better. dont know if its due to ghk or if its due to injecteble copper

I also saw this, a guy pushing the dose to 20mg and had insaine results

https://imgur.com/Rj1pBxx

@Lordallmighty said:

GHK Cu is great too.
I started at 5mg, now at 10mg per day