<?xml version="1.0" encoding="UTF-8"?><rss xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:atom="http://www.w3.org/2005/Atom" version="2.0"><channel><title><![CDATA[Evodiamine, anyone taking this?]]></title><description><![CDATA[<p dir="auto">It appears to be quite interesting.</p>
<ul>
<li>Inhibits the differentiation of preadipocytes into mature adipocytes (fat cells).</li>
<li>Upregulates uncoupling/thermogenesis via an UCP-independent pathway.</li>
<li>Inhibits Calcium-activated Chlorid Channels, therefore limits vasoconstriction and may lower hypertension and improve wound healing etc.</li>
</ul>
<p dir="auto">I haven't found it as a dedicated supplement but only with a puny 10mg as part of some "fat burner"-blends.<br />
Probably 100-200mg would be more adequate?<br />
It's extracted from a plant traditional and endemic to China and Korea, so no short supply of the powder.</p>
<p dir="auto">On the downside: <em>&gt; it is also found that it has significant hepatotoxicity and cardiotoxicity,</em> although this may be dose-dependent and I haven't specifically checked up on it yet<br />
<a href="https://www.sciencedirect.com/science/article/abs/pii/S0378874120330464" rel="nofollow ugc">Evodiamine: A review of its pharmacology, toxicity, pharmacokinetics and preparation researches, 2020</a></p>
<p dir="auto">No acute effects, likely more medium-term:<br />
<a href="https://www.sciencedirect.com/science/article/abs/pii/S0271531713001930" rel="nofollow ugc">Capsaicin and evodiamine ingestion does not augment energy expenditure and fat oxidation at rest or after moderately-intense exercise, 2013</a></p>
<p dir="auto"><a href="https://www.sciencedirect.com/science/article/pii/S1756464615004491" rel="nofollow ugc">Dietary supplementation with evodiamine prevents obesity and improves insulin resistance in ageing mice</a></p>
]]></description><link>https://bioenergetic.forum/topic/9412/evodiamine-anyone-taking-this</link><generator>RSS for Node</generator><lastBuildDate>Mon, 15 Jun 2026 04:57:27 GMT</lastBuildDate><atom:link href="https://bioenergetic.forum/topic/9412.rss" rel="self" type="application/rss+xml"/><pubDate>Sun, 14 Jun 2026 18:56:37 GMT</pubDate><ttl>60</ttl><item><title><![CDATA[Reply to Evodiamine, anyone taking this? on Sun, 14 Jun 2026 22:09:10 GMT]]></title><description><![CDATA[<p dir="auto"><a class="plugin-mentions-user plugin-mentions-a" href="/user/crumblingcookie" aria-label="Profile: CrumblingCookie">@<bdi>CrumblingCookie</bdi></a> interested in hearing more about this.</p>
]]></description><link>https://bioenergetic.forum/post/65010</link><guid isPermaLink="true">https://bioenergetic.forum/post/65010</guid><dc:creator><![CDATA[LetTheRedeemed]]></dc:creator><pubDate>Sun, 14 Jun 2026 22:09:10 GMT</pubDate></item></channel></rss>