Peritol/periactin (cyproheptadine) - my experiences
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As I have been taking 4-8 mg of cyproheptadine for 2-3 weeks, I would like to share my thoughts and experiences:
During the first 3 days of taking cyproheptadine, I did not experience any significant symptoms, apart from noticeable sedation. Therefore, I decided to take the cypro at night instead of during the day. The first effects started appearing on the 4th or 5th day, when for the first time in years, I experienced what it was like to have deep sleep. As a result, my sleep duration increased from 6/7 hours per night to as much as 10 hours. This is likely related to an extension of the REM sleep phase and lower cortisol levels, due to the antagonism of 5-HT2A and 5-HT2C receptors. Additionally, my nasal breathing comfort improved, as I had been experiencing noticeable nasal issues due to excess histamine. However, I find it hard to wake up in the morning, with no passion for action, as I strongly desire to prolong my sleep (due to vivid dreams). After 7 days, every sleep phase had sexual content, and I frequently experienced nocturnal emissions, with morning erections. During the day, I felt more calm, controlled, and less aggressive, with a significant increase in libido (due to serotonin antagonism).
The problem I face is a lack of motivation, which is more likely related to my ADHD. Cyproheptadine antagonizes dopaminergic and cholinergic receptors, so during its use, I often resort to nicotine and caffeine.
I stopped taking it in the morning due to cognitive impairment; it became harder for me to formulate thoughts, and my vocabulary seemed more limited. This is related to acetylcholine, so I started experimenting with higher doses of nicotine from snuff.
I rate the experience 8/10. For those struggling with sleep, allergies, and aggression, I recommend it. However, due to the antagonism of dopamine and acetylcholine receptors, I suggest taking it cyclically during periods that don't require intense mental effort, such as holidays, to avoid unnecessary repercussions.
I would like to emphasize, however, that when there is no major issue with signaling, I believe the need for medication is unjustified. It’s not a vitamin, mineral, or another supplement—it’s a drug, so one must keep in mind that it can cause harm. Many people have mixed feelings about cyproheptadine, and I don’t blame them, because many people simply cannot benefit from it or don’t need it. First and foremost, I recommend trying a diet (especially one that limits protein—particularly tryptophan—and focuses on glycine and proline), as well as one rich in carbohydrates, because fats (especially oleic acid) have serotoninergic effects.
,,Discovery consists of looking at the same thing as everyone else and thinking something different." - Albert Szent-Gyorgyi
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Although I generally feel an improvement in my health, especially in terms of breathing (I used to have severe seizures combined with heart palpitations and anxiety), this is now rare. I have mentioned before that serotonin is critical for lung and bronchial health, not in the sense that it absolutely harms, but that excessive hyper-receptor signaling leads to disturbances in gas exchange and promotes fibrosis. The "awakening" effect caused by serotoninergic activation in response to hypercapnia is well known (source). Serotonin receptors, in fact, behave like chemoreceptors. What is most important, however, is that the response depends on the amount of the signaling molecule, and often an increase in the number of receptors on the cell induces an exaggerated response to carbon dioxide, which I believe I have experienced. Now, even when working out at the gym, I no longer experience heart palpitations or difficulty breathing, and I also experience lower arousal in response to a training session. Is this related to cyproheptadine? I don’t know. I suspect it's more related to my diet and proper supplementation (I take a teaspoon of baking soda with a liter of freshly squeezed juice before training).
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Piribedil nukes adhd
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@thyroidchor27 said in Peritol/periactin (cyproheptadine) - my experiences:
Piribedil nukes adhd
I prefer cocaine.
