@yerrag , The statin side effects seem quite insidious (!), based on the paper in the OP:
Due to their lowering the protein prenylation, they possess anti-inflammatory properties, yet due to lowering the same protein, they activate a immune response (via an NLPR3 immunosome), which in its turn may increase the LPS absorption.
"In general, statins are associated with anti-inflammatory responses that are related to cardiovascular benefits (49). However, as we and others have shown, statins can generate a specific pro-inflammatory response by activating the NLRP3 inflammasome (12, 13)."
Secondly, statins activate the TLR4 receptor, which is a marker of metabolic endotoxemia.
"We found that statin feeding and LPS injections in mice both alter gut barrier function and metabolic endotoxemia (amount of TLR4 activity in the serum)."
The statin insidiousness is doubly bad because the LPS and myopathy side effects exist but are not readily observed with a low dose of statins.
And, extrapolating from the paper (if I may), when a lot of LPS is already in your body, the side effects magnify.