Categories

• Bioenergetics Discussion

  Place to discuss the work of Ray Peat, Otto Warburg, Albert Szent-Györgyi and the interdependence of energy and structure

  • Literature Review
  • Ray Peat Resources
  • Not Medical Advice
  • Products
  • The Kitchen
  • The Gym
  4k Topics

  36k Posts

  J

  @wester130 I doubt that will feel anything from DHEA and progesterone at that dose. But the exemestane is potent enough to have an effect. All you can do is try and see what produces the most benefits for you. The good news is that even if you think you made a mistake (which at these very low doses is not really a concern), your hormones will stabilize within a few days. For instance, I've taken 400mg pregnenolone and 50mg DHEA and 12.5mg exemestane and didn't experience anything wild. I've also taken various doses of exemestane without DHEA/progesterone. Any low estrogen symptoms go away within 1-3 days of ceasing A.I. administration.
• Case Studies

  Discussion of individual human or animal cases. "There is no foreseeable limit to the qualitative development of the economy." - Ray Peat, Generative Energy

  • Experimental Logs
  245 Topics

  3k Posts

  W

  @sunsunsun PUFA can lower metabolism so your body runs better on less and needs less much of that motivation will be from stress and from estrogen
• The Noosphere

  Discussion of culture, literature, and politics

  • Art
  • Current Events
  • Bioenergetic Development
  • Philosophy
  • Esoteric, Paranormal, & Consciousness
  198 Topics

  4k Posts

  J

  https://www.youtube.com/watch?v=YO7M0Hx_1D8 https://www.youtube.com/watch?v=kMXBJW1PuU8
• Meta

  Conversations about Bioenergetic Forum
  87 Topics

  1k Posts

  K

  @lobotomize Good framework, though the evidence-grade weighting in the default sort might bury solid animal/mechanistic work under mediocre human studies. Letting people re-weight it themselves could help. Bigger gap: how do contested claims get handled? If a newer RCT contradicts an older one, does the old card get flagged/archived, or do they just sit side by side? That seems like the whole point of avoiding rediscovery. Also worth adding a required sample size field to the submission template — two "Evidence B" studies can carry very different weight depending on n, and that gets lost if it's folded into the letter grade alone. Export for meta-analysis is a nice touch though.
• The Junkyard

  Off-topic or unclear threads sent here. But dig around and you might find some gems.
  524 Topics

  15k Posts

  E

  @sunsunsun did you try this? I'm curious about alcohol for the lipofuscin clearing and nothing else