@metabolicmilk

I could not get vitamin E to mix with DMSO, I would not recommend this. Unless you’re talking about dissolving d-alpha tocopherol acetate in DMSO. That may well work, but according to Ray the acetate ester is about 50% as effective as the nonesterified tocopherols.

@wester130 said in Thyroid Therapy for Chronic Digestive Issues:

I am not sure why thyroid hormone would magically solve digestion

Not magically but indirectly.
If nutrients are required for digestive enzymes (poor and long-lasting digestion), leaving metabolic enzymes not sufficient, from one hand, and if you suffer from low-grade inflammation, on the other hand (arthrosis or gluten 3 times a day which has an impact on zonulin and the tight junctions of the intestines) you can’t optimize the communication from the HPA axis and the central operator for energy (thyroid).
B6 is stolen with low-grade inflammation. B1 is stolen with rice and bread. Not enough. Energy metabolism requires appropriate levels of several B-vitamins. Not only.
So poor digestion impacts the energy level, directly and indirectly. Stress level too.
I can give a link for B1 and B6, in connection with the brain, if desired.
Expressed differently: Interconnection between the brain and the stomach, through steroid hormones.
Not directly but indirectly.

Additional info for the other readers:
Test for steroid hormone :

adrenal: HPA axis + rt3 FT3 FT4 sex hormones: testosterone, estrogen, cortisol
Why is cortisol needed for other hormones to work properly? For some effects (e.g. libido, energy levels, thermoregulation) adequate levels of not just one but multiple or even all of the major hormones are needed. Cortisol and thyroid hormones determine our energy levels

How much “energy” a person has, is to a large extent determined by someone’s levels of thyroid and adrenal hormones. Whereas thyroid hormones set the “idle” state for our system (i.e. the state of how much “background”-energy someone has), levels of cortisol are the “gas pedal” (i.e. they are one of the most important factors that determine moment-to-moment energy levels and wakefulness).
However, in order for thyroid hormones to exert their effects properly, adequate levels of cortisol are needed — and vice versa. Therefore, both hormones are needed in adequate levels for each other to work as they should and whenever one of these hormones is low, energy levels will be as well. In fact, replacement of thyroid hormones and/or adrenal hormones are often enough to “give people their life back”.
PS: And I haven't yet talked about the microbiota 😉
70 % of our immune system.

@jgs130

Tell me, if you are such a stickler for evidence, what constitutes evidence for you? Do you need a trial to be made by the FDA, in the way that they asked for evidence for Ivermectin?

Or do you need 10 people in this forum saying so?

You give examples of Ray correcting Kate, yet because you say so that Ray corrected Kate on the matter of progesterone, without yourself giving us an actual example, but you just say so, and even saying he corrected her many times, stretching your point, isn't even enough evidence. Without proof, you give the appearance you know what you're talking about.

The reason this world is so fucked up is because there are so many know nothings like you is because you depend on experts to give you evidence while evidence is not necessarily the first thing to look for.

The first thing is to establish ground for why you believe such is such. Then you a hypothesis. It becomes a theory. Then becomes a law as more evidence is gathered to bolster that hypothesis.

But evidence is not always necessary, as people have worked off theories.

Why do people use TCM, herbs, and aromatherapy despite the FDA or some meddling agency came to act as judge and jury for evidence?

You are a programmed scientism evidence-based zealot raised to depend on titles and degrees to establish credibility, with no iota of training in logic and reason. But the greatest healers in history have not depended solely on the "scientific method' to heal people.

Tell me, what does progesterone do, and why is it safe for anyone to use? Do you know what a hormone does? If it's so safe as you would say it is, why don't you try to OD on it?

You simply have no idea, do you? You don't even understand the way the body works. It is not an entity that runs off magical bullets that the medical industry tends to rely on to alleviate symptoms without fixing the root cause of a problem. Yet you are such a fool for thinking of progesterone as one such substance.

Without the kind of thinking that the body runs in a complex web of interrelationships that would be called cycles. If you are on a virtuous cycle, you are in good balance and health. But when you are in a vicious cycle, you are in poor health, and will likely stay so unless you break that cycle. But this has no meaning for a dolt like you.

Now off you go in your search for an Elysium device to entertain your medical fantasies!

@cs3000 What's weird is that I don't notice any symptoms. Maybe the progesterone is saving me from symptoms that I otherwise couldn't help but notice.
Thanks for your reply.

It really does sound as if you're very lactose intolerant. Homemade yogurt, when made properly, will have no lactose at all. Most recipes start with a gallon of milk but I suggest that you make a half batch first. Definitely drain it to make it thicker/more palatable. Use the whey in baked goods or drink it straight or in smoothies. Good luck!

So sad to hear, he helped so many people get better.

@NoeticJuice So true. This is how I feel without alcohol to dumb me down lol. Most of the time I'm fine with being high IQ and energized around the right friends, but around certain people I'm better off drunk and stupider.

@Appa

Sorry for replying very late. A few things got me busy and I had been wanting to reply but it took so long before aibgot freed up and by then I could not find it in my alerts anymore.

First off, saliva pH should always be around 1 pH higher than urine pH. If ever urine pH us higher than saliva pH, there is something really off such that this inversion occurs.

Now let me talk about the other deep end of it, where acid-base balance is optimal. To give you a perspective from that side, so you can understand where you are at currently.

When everything is peachy, you urine is more likely to be acidic, because most of the time, our body is getting rid of acidic waste. So do not expect much out of getting a pH of 7 from urine. A pH of 7 is expected from distilled water, which is neutral. But with urine, when during the day you get a value of 6.4-6.6, you are looking at the optimal pH. So long as the first criteria is met (saliva pH at around 1 pH above urine pH).

This is when you have all sources of acidity minimized in the body. Metabolically, you are running heavily on mitochondrial oxidation, producing CO2 which is a pH buffer, and producing a minimum of lactic acid and keto acids from the other metabolic pathways. Your body is not fighting off toxins and infections, nor are you taking drugs that are acidic. But there are acidic foods you take such as meat, which is a necessary tradeoff to getting nutrients from food.

Which is why when during the day, when you're not sleeping and eat, it is normal to see your urine pH go down to 5.5 or even lower to 4.5, as long as the first criteria is met (which I already described. Back read if you forget). At night, when we sleep, our lungs and kidneys are actively at work rebalancing our acid-base pH balance to make up for the acids we produce during the day. When you wake up at night and see your urine pH at 6,4- 7.2, you are seeing the effect of your kidneys and lungs at work and catching up by restoring your balance. Day in and out, you have a body that is able to provide you a basic foundation of health arising from having acid-base balance. Your body is a good terrain where disease does not step in like any uninvited stranger into your home. For me, this is how you can be assured you don't get cancer.

If your urine pH is 10, it is very likely your saliva is going to have a pH that is less than your urine. Your saliva being more acidic than your urine is a very bad sign.

Before I proceed with why, as this requires a lot of explanation, can you test both your urine and saliva pH and give me the values?

@DavidPS Nice summary!

@Fructose Nearly 6 months later, is this still working for you? Has it gotten better/worse or stayed the same?

@metabolicmilk Hello, I know its a slight necro but I'm wondering if you have gone ahead and tried what you describe here. I myself am also running a very similar experiment using pansterone, pregnenolone, and some tyromix in conjunction with small doses of DHT (5-10 mg a day) to see what happens, and especially curious about whether this stack will increase or decrease endogenous androgen production after removing DHT and eventually cycling off other components as well (I don't really want a hormone permastack the way you would do for vitamins, mostly I want to shift my body into a certain state and then use more gentle/natural things to sustain it)

@Ecstatic_Hamster - I have been playing with slowing my breathing in accordance with this video linked below.
30 Second Exercise to Build Up Your CO2 Tolerance | Part 1

Supplementing sodium as salt and baking soda throughout the day seems to really help my debillitating fatigue / depression.

This one's a goodie, have only listened to half of it but have already learned a few new things. Thank you David, this will soon be passed on to my own circles.

@noodlecat59 Saving me research time is much appreciated.

I do remember Georgi commenting on methylene blue becoming a serotonin agonist if too much is taken and that was the reason for 15 mg daily limit and for not taking it every day.

Quick update: LH and FSH labs came in.

FSH seems normal at 7.7mIU/mL (range is 1.5–12.4)

LH is quite high at 9.0mIU/mL (range is 1.7–8.6)

Current hypothesis is that the microlithiasis is a result of atrophy and not a cause (ruling out calcium regulation issue unless PTH/calcitriol labs come back abnormal).

I also think that the high LH indicates primary hypogonadism rather than secondary.

Still in the dark about a cause, however. The fact that it's only one testicle seems very bizarre. Going to get in with a good urologist to see if they can tell me more. I'll also ask the radiology lab for the ultrasound images and post them here.

In the meantime—any pointers on lowering LH are welcome. I've read that high levels in the blood cause aromatization so will try to ameliorate that.

@Crypt-Keeper I agree with your point in why not spread it out in the day?

Im not a proponent for IF at all.

I think the MSM or even the guy himself thinks THAT’S why he is remaining lean with mass.
That it is the IF-
And I don’t agree with that at all

What’s good
Is that he’s balanced macros
So that is a huge benefit