@questforhealth said in I am literally part Neanderthal - how can I live a good life???:

OR all this is bs and used to cover up actual causes of disease??

That or a rabbit hole not worth pursuing.

And look on the bright side, at least chances are you don't have Flores man genes 🦍

@PeaterParrot

I personally have not seen convincing evidence that aspirin would delay a shoulder injury repair. Aspirin has been shown to protect against excessive inflammation and scar formation in tendon repair.

@basednigga2006 dont overdo it, but maybe a few extra cups and see how you do.

@questforhealth I think the high concentration of B vitamins and magnesium far outweighs the cost of the high MUFA ratio, especially if you eat lean cuts.

I just ate a single pork chop and I already feel so much better, it's a life saver right now.

@Buckian

I've had some good results from bicarb intake. I noticed this after having Gerolsteiner for the first time- it has a pretty high bicarb content and I felt really good afterwards. From what I've seen about bicarb and bacteria, bicarb in fairly low concentrations can be a potent antagonist of pathogenic bacteria metabolism and boosts innate immunity effects against bacterial infections; it also boosts antibiotics(except for tetracyclines due to pH effects). This goes for respiratory and oral bacteria, which I have a personal desire to protect myself from.

I wouldn't say that I take it because it gives me some particular feeling, but that it's easy to incorporate into my routine and covers several bases.

OJ for the pre-sleep sugar, baking soda is there to help with inflammation and bacterial inhibition to avoid night time serotonin surge. I have a history of insomnia and difficulty sleeping, so dealing with serotonin around sleep time through sugar and salt has been a big help.

Baking soda is sodium bicarb, so I get the sodium, the sugar from OJ, and the inhibitions from the bicarb. My rough math is that my bicarb to OJ ratio is high for inhibition concentrations. I usually do a small glass(4-6 oz) with 1 tsp baking soda(lightly packed). That's about 7g bicarb in 6 oz, which would be 37g in 1L or ~600mmol/L. That's well above the minimum concentration for inhibition(23-182mmol/L) and about 20% less than a minimum bactericidal concentration. I'm not going for an antibacterial effect, inhibition is good enough for me especially as I have a pretty healthy gut microbiome.

@Sophocles you are fortunate then!

@bengobeil said in Grounding is the single greatest “biohack” I’ve ever found:

While testing with a multimeter, I discovered the the wire that came with the mat wasn't conducting anymore!

Why do you think this happened? Is is the bad quality of the mat you purchased, or something else?

@CO3 The question is what is the metabolic link between socioeconomic status and longevity? I suppose happiness/lower stress is the obvious factor but I suspect there are other psychological and physiological effects of power

@flexthorton Another option would be for you to consider physicians that are listed with Orthomolecular.org that treat endocrine issues. See here: http://orthomolecular.org/resources/pract.shtml

@Orindere

The only ones I’ve ever used and think are trustworthy are Idealabs Tocovit and HealthNatura Whole E. I’d love more options or suggestions if anyone has.

@arkos I’m in a similar position.

I’m super sluggish in the morning too. Usually pretty congested and eyes get puffy. I think it’s cause my metabolism gets so low over night. But it cranks back up to 98.6. Especially with bits of t3. I’m taking a small amount of cynoplus hoping to get my morning temp up.

But at least cortisol isn’t cranking so high in the morning to make the temps high. But also maybe my circadian rhythm is flipped cause usually the evening is when I really feel energized

@linx Have you ever tried combination T3/T4 therapy? Over what timeline have you worked up to 87.5mcg T3 daily?

@Ray-Peat-Fanboy High iodine intake, without sufficient micronutrient support, increases the risk of Hashimoto's, especially in women. Selenium seems to plays a crucial role in protecting the thyroid from further tissue damage caused by excess iodine intake.

@evan-hinkle

There is a study I will try to find later that assessed medications dissolved in Vit E and their accumulation in the brain after traumatic brain injury, IIRC.

Vit E significantly improved accumulation in the brain, Vit E itself accumulates in the brain and the liver(other places too, but these two are the most accumulating). This makes sense due to the sensitivity of each organ to lipid peroxidation, cell membrane disruption, etc.

@CO3 I found the issue. Once in a while I eat mushrooms but I cook them only for half an hour and it requires at least 2 hours of boiling.
The endotoxin and bloating that this created increased the intensity of nightmares.
Now I stopped them and I don't have them anymore.
Maybe also the high amount of copper does something I don't know. I was eating 500,g a day.

@John-Smith lol

@deliciousowl yes its opiod. I think even that is too much I never go above 12 mg a day and I only use it three times a week. serotonin is generally androgen inhibitory and I dont think the opiod agonism outweighs the pro sero- inhibitors effects on T at that dose

My biggest success is treating it before symptoms appear. Slam yourself with Vit D and C every time you get little to no sleep.