@Chud Bruh peat like crazy and you will see changes.

@ora said in Fish oil kills neurons, Coconut oil dilutes this: That study is pretty poorly run. I Yes, indeed. Well seen. Not realist. And moreover: 8 weeks is to short to see deep deleterious effects. When specifying "vitamin alpha-tocopherol" is not sufficient. I don't take into account studies with dl-toco (synthetic). Less efficient. "the fatty acid composition of brain PUFA was significantly altered, even if alpha-tocopherol was added to the salmon-oil diet."

@annis that's cool,thx

@Peatful thanks I will reread this!

@Sugarnotsnow Nice to know. My uric acid is always high, but I let it stay high as it doesn't bother me and it is an underappreciated part of the body's primary antioxidant system. My body must need it as my kidneys do not allow much of it to be excreted as I excrete much less of it than reference range The body seems to know I need to deal with a high level of oxidative stress and uric acid being high provides me with a high level of protection. Since I keep close tabs on maintaining good acid base balance,the uric acid does not precipitate on my joints and I don't have any arthritic pain nor gout.

@Sugarnotsnow I decode: 2.6 and 1.3 year benefit (with 2 kinds of measure). DNAmAA did not statistically differ between participants. Therefore we concluded vitamin D supplement is associated with lower DNAmAA with vitamin D deficiency. My reading: How the hell can they say 2 different things in the conclusion! (no statistically difference and lower methylation of DNA). A clue: The sponsors of the study are also the financiers. They will only read the conclusion.

I used to engage in intermittent fasting so I am wary of people touting a diet of mostly liquids, but it’s so much different when a person is drinking highly nutritious things that are high in glucose. I think Dr. Peat has said simply giving the digestion a break can dramatically lower the inflammation caused by general food-based irritation.

@wester130 said in Share your PUFA story: vitamin e, niacinamide, taurine/zinc can protect you from PUFA Don't forget coconut oil and aspirin have protective effects as well If i'm not mistaken i believe we already have a PUFA experience thread.

@psi I believe it also is succeptible to heavy metal contamination.

Below are some thoughts on recent changes to my treatment protocol: Thyroid dosage remains at half cynoplus and half cynomel tablet nibbled throughout the day, with the occassional quarter or eighth cynomel tablet added after my afternoon snack depending on pulse and temperature. Latest thyroid blood panel results are nearly identical to the last panel I pasted in this thread, and so are not worth repasting Adrenal overactivity, which previously caused cold feet and contributed to gastrointestinal issues, seems to have resolved after removing caffeine from my diet. As an unexpected result, my chronic pelvic soreness, while not entirely reduced, has improved somewhat. Effects of thyroid medication do also seem more potent after removing caffeine. Some ideas for why this might be are that improved adrenal function potentiates the effect of thyroid hormone (think of the synergistic effects of cortisol and thyroid when in proper ratio) or that my metabolism was burning too hot, causing an energy deficiency and preventing the thyroid meds from having their full effect All glutenous carbs have been removed from my diet. After doing a short elimination diet, I've determined that even sourdough bread, home-baked and well-fermented, now provokes an autoimmune response. Otherwise, diet now consists almost entirely of fruit, milk, eggs, and meat One rounded tablespoon of baking soda before bed has, after only a week, resulted in some improvement to gastrointestinal issues. It has reliably increased transit speed and seems, I think, to be causing more fungal biofilm elements to be excreted in stool. More time required to assess true efficacy Recent experiments supplementing with moderate to high dosages of calcium carbonate (1-2g), potassium gluconate (500-800mg), methylene blue (5-15mg), ox bile, prescription digestive enzymes, berberine, grade seed extract, bromelain, and L-glutamine have not resulted in any meaningful symptom improvement I'm considering retrying high-dose allicin. The last time I did this, I experienced significant symptom relief, albeit temporarily, when taken with each meal. The benefits of allicin supplementation may have been curbed when I (quite stupidly) started taking bismuth subsalicylate before meals, which binds to and neutralizes intestinal sulfur (forming the black chemical compound bismuth sulfide), and which likely negated the antifungal effects of the allicin. Sometimes the results of our self-experiments only make sense in retrospect, and only after several months of brooding on why they were successful All in all, nothing too significant to report back on; my digestive symptoms persist, with minor improvements here and there. I'm beginning a new business venture next month, so I'm hoping to see some more improvement before then; but if not, I'll continue researching, experimenting, and working hard to regain my health. Cheers to all of you; I hope the summer sun has kept you warm and energized.