@Peatful thanks I will reread this!

@Sugarnotsnow Nice to know. My uric acid is always high, but I let it stay high as it doesn't bother me and it is an underappreciated part of the body's primary antioxidant system. My body must need it as my kidneys do not allow much of it to be excreted as I excrete much less of it than reference range The body seems to know I need to deal with a high level of oxidative stress and uric acid being high provides me with a high level of protection. Since I keep close tabs on maintaining good acid base balance,the uric acid does not precipitate on my joints and I don't have any arthritic pain nor gout.

@Sugarnotsnow I decode: 2.6 and 1.3 year benefit (with 2 kinds of measure). DNAmAA did not statistically differ between participants. Therefore we concluded vitamin D supplement is associated with lower DNAmAA with vitamin D deficiency. My reading: How the hell can they say 2 different things in the conclusion! (no statistically difference and lower methylation of DNA). A clue: The sponsors of the study are also the financiers. They will only read the conclusion.

I used to engage in intermittent fasting so I am wary of people touting a diet of mostly liquids, but it’s so much different when a person is drinking highly nutritious things that are high in glucose. I think Dr. Peat has said simply giving the digestion a break can dramatically lower the inflammation caused by general food-based irritation.

@wester130 said in Share your PUFA story: vitamin e, niacinamide, taurine/zinc can protect you from PUFA Don't forget coconut oil and aspirin have protective effects as well If i'm not mistaken i believe we already have a PUFA experience thread.

@psi I believe it also is succeptible to heavy metal contamination.

Below are some thoughts on recent changes to my treatment protocol: Thyroid dosage remains at half cynoplus and half cynomel tablet nibbled throughout the day, with the occassional quarter or eighth cynomel tablet added after my afternoon snack depending on pulse and temperature. Latest thyroid blood panel results are nearly identical to the last panel I pasted in this thread, and so are not worth repasting Adrenal overactivity, which previously caused cold feet and contributed to gastrointestinal issues, seems to have resolved after removing caffeine from my diet. As an unexpected result, my chronic pelvic soreness, while not entirely reduced, has improved somewhat. Effects of thyroid medication do also seem more potent after removing caffeine. Some ideas for why this might be are that improved adrenal function potentiates the effect of thyroid hormone (think of the synergistic effects of cortisol and thyroid when in proper ratio) or that my metabolism was burning too hot, causing an energy deficiency and preventing the thyroid meds from having their full effect All glutenous carbs have been removed from my diet. After doing a short elimination diet, I've determined that even sourdough bread, home-baked and well-fermented, now provokes an autoimmune response. Otherwise, diet now consists almost entirely of fruit, milk, eggs, and meat One rounded tablespoon of baking soda before bed has, after only a week, resulted in some improvement to gastrointestinal issues. It has reliably increased transit speed and seems, I think, to be causing more fungal biofilm elements to be excreted in stool. More time required to assess true efficacy Recent experiments supplementing with moderate to high dosages of calcium carbonate (1-2g), potassium gluconate (500-800mg), methylene blue (5-15mg), ox bile, prescription digestive enzymes, berberine, grade seed extract, bromelain, and L-glutamine have not resulted in any meaningful symptom improvement I'm considering retrying high-dose allicin. The last time I did this, I experienced significant symptom relief, albeit temporarily, when taken with each meal. The benefits of allicin supplementation may have been curbed when I (quite stupidly) started taking bismuth subsalicylate before meals, which binds to and neutralizes intestinal sulfur (forming the black chemical compound bismuth sulfide), and which likely negated the antifungal effects of the allicin. Sometimes the results of our self-experiments only make sense in retrospect, and only after several months of brooding on why they were successful All in all, nothing too significant to report back on; my digestive symptoms persist, with minor improvements here and there. I'm beginning a new business venture next month, so I'm hoping to see some more improvement before then; but if not, I'll continue researching, experimenting, and working hard to regain my health. Cheers to all of you; I hope the summer sun has kept you warm and energized.

@jgs130 Tell me, if you are such a stickler for evidence, what constitutes evidence for you? Do you need a trial to be made by the FDA, in the way that they asked for evidence for Ivermectin? Or do you need 10 people in this forum saying so? You give examples of Ray correcting Kate, yet because you say so that Ray corrected Kate on the matter of progesterone, without yourself giving us an actual example, but you just say so, and even saying he corrected her many times, stretching your point, isn't even enough evidence. Without proof, you give the appearance you know what you're talking about. The reason this world is so fucked up is because there are so many know nothings like you is because you depend on experts to give you evidence while evidence is not necessarily the first thing to look for. The first thing is to establish ground for why you believe such is such. Then you a hypothesis. It becomes a theory. Then becomes a law as more evidence is gathered to bolster that hypothesis. But evidence is not always necessary, as people have worked off theories. Why do people use TCM, herbs, and aromatherapy despite the FDA or some meddling agency came to act as judge and jury for evidence? You are a programmed scientism evidence-based zealot raised to depend on titles and degrees to establish credibility, with no iota of training in logic and reason. But the greatest healers in history have not depended solely on the "scientific method' to heal people. Tell me, what does progesterone do, and why is it safe for anyone to use? Do you know what a hormone does? If it's so safe as you would say it is, why don't you try to OD on it? You simply have no idea, do you? You don't even understand the way the body works. It is not an entity that runs off magical bullets that the medical industry tends to rely on to alleviate symptoms without fixing the root cause of a problem. Yet you are such a fool for thinking of progesterone as one such substance. Without the kind of thinking that the body runs in a complex web of interrelationships that would be called cycles. If you are on a virtuous cycle, you are in good balance and health. But when you are in a vicious cycle, you are in poor health, and will likely stay so unless you break that cycle. But this has no meaning for a dolt like you. Now off you go in your search for an Elysium device to entertain your medical fantasies!

@cs3000 What's weird is that I don't notice any symptoms. Maybe the progesterone is saving me from symptoms that I otherwise couldn't help but notice. Thanks for your reply.