Well I guess Jacob was preferred by God to Esau. So there's that.

@dht said in DHT Enanthate:

The few people hyping up DHT Enanthate on twitter are using exogenous T and E2 alongside DHT.

Are there any good semi-legal-ish sources of E2? I'm definitely deficient and it's just awful.

@alfredoolivas And from that study:

In conclusion, our work demonstrates that the fat-burning action of T is dependent on aromatization into estrogens and is at least partially mediated by the stimulation of physical activity via extrahypothalamic ERα signaling.

That definitely won't go over well with some in this community that insist that estrogen is the enemy and DHT is good because it supposedly crashes it.

Want the effects of DHT-e? Simply take plain DHT 4-5x a day.

I still can't get a good explanation for what good effect people think exogeneous DHT has. A large, large portion of it is converted into estrogens 3α-androstanediol and 3β-androstanediol, which bind to both ERα and ERβ, to the latter with better affinity, and does not bind to androgen receptors. The enzymes that convert DHT to these hormones are 3α-HSD and 3β-HSD and are abundant in the liver, skin, muscle and brain and are metabolizing all of that DHT you're putting into your blood. In the brain, 3α-androstanediol is responsible for the pro-GABA effects and 3β-androstanediol for the anxiolytic effects and also the regulation of hormone production through (the suppression of) the HPTA.

If you want DHT's effects in the muscle you need to take something artificial that can't be 3β-HSD reduced, like anavar.

Otherwise, with DHT being a paracrine hormone in tissues where it has an important effect, it seems better to supplement with the pro-hormone (T) and support 5α-reductase production.

@alfredoolivas I've tried the following:

• 50mg DHT / ml DMSO
• 100mg T / ml DMSO
• 100mg T / ml 95% alcohol

Both DMSO solutions leave visible crystals / white residue on the skin after drying. The alcohol solution didn't have any visible crystals on the skin after drying, but there is residue on my dark-colored undershirt.

In all cases the solutions were completely clear (no crystals) in the dropper bottle, so I think they're being dissolved well.

Looks like 70% alcohol + 30% IPM doesn't allow for T to penetrate the skin in my case. Same as DMSO. It also dries incredibly fast (within seconds). I could try throwing some MCT oil in there to prevent the quick drying but I doubt it would make a difference for penetration.

I've finally gotten around to trying T in 95% alcohol + IPM. Started with 50mg T. I'll check in later if I notice anything.

Only thing different so far vs. DMSO is that I don't notice any crystals on my skin after drying, and of course none of the nasty DMSO smell. So I think that's a good start.

@Kilgore I could not get T to dissolve in a reasonable amount of Vit E. It's just not a good solvent alone. There's a thread somewhere that I posted in awhile ago.

BTW, Santosh was one of the pioneers of these various PPL test powders in transdermal form and one of the last posts he made before he went radio silent was to stay away from DHT stuff as it nukes estrogen too much. Just putting it out there.