@Mauritio high dose niacinamide is not nearly as effective in vivo for dogs against what im pretty sure is mallessezia compared to a normal dose of fluconazole. and ketoconazole seems about the same as fluconazole. no experience with itraconazole but will prob try it at some point, it is very expensive in north america or europe. just observations not really scientific. in humans iirc terbinfine might be pretty good for mallessezia but in dogs they excrete it too quickly apparently.
if a dog has itchy ear , one dose of fluconazole will knock it out for a couple weeks. no need to give everyday.
imo cancer patients could probably all try an antimicrobial protocol with an antibiotic, antifungal, and antiparasite drug. reaearchers keep looking for a side target of the above drugs but im guessing the actual antimicrobial part is probably anticarcinigenic
i also have seen evidence anti serotonin drugs are anti parasite. theres a study on cyproheptadine being an anti parasite drug, from https://www.cabidigitallibrary.org/doi/full/10.5555/19900860028?__cf_chl_tk=ThtQHEaB7fbCcC9qnD19tIV6PYSAm9plCdzDERWJ0R0-1775529914-1.0.1.1-pMIrmBv2QC7gUB4mLmBDUGspQSWjaQ7agFuosFIZ.fI
