Okay it's now quite obvious that the digestive issue is SIBO.

• It happens with any type of starch, even the ones that should always be fully digested before they reach the big intestine (e.g. potatoes and rice)
• It happens very soon after eating, before anything can even reach the large intestine.
• So it must happen in the small intestine, it must happen because of starch and since I don't feel ill from eating (just highly stressed) it is not leaky gut.

Last two days I have no eaten any starch and I am doing pretty good. Tired a lot, but in a way that allows me to relax, which would be impossible if cortisol was elevated. Appetite, which is also a good sign, mostly for starchy food but I will have to get over that. Nimble enough to do figurative drawing, which was not possible while Serotonin was elevated.

I have a rough idea what I need to eat; keeping calories from fat below 20% to stay in gluccose burning mode. (Mostly yoghurt, fruit toppings, milk, grape juice, cheese, maybe some soup.) Plan to use garlic as antibiotic.

Supplementation wise I keep it simple with Thiamine, Thyroid, Zink and a 2€ drug store vitamin B complex.

@LucH Thank you!

@LucH

Okay a bit different topic. Had an argument. Adrenaline spikes. Obviously not optimal. But sometimes it is involuntary, and I would prefer to make the most out of the energy as long as I have it instead of it just being evaporated as heat and angry thoughts. For example right now it will probably be the fuel for writing that diet plan.

What can I do to ensure that the adrenaline does as little damage as possible? Eat large amounts of sugar so that less protein needs to be cannibalized to raise the blood sugar? Protein to offset the loss? High B vitamins to ensure sugar metabolism works without a issue?

@LucH Okay, you are saying that basically I need to make a diet + supplement plan that covers all basic nutrients without irritation so the gut can heal without further complications correct?

Sorry for being slow on the uptake, I am still dealing with the kind of low energy brainfog so I was only thinking about the immediate next steps.

Ate extra Carbs and now I am happy again

Huh, there might be something to that. Probably reduced carb intake too much in the attempt to avoid the irritation from the wheat.

@LucH

I haven't really found the energy to write a proper reply lately so sorry for this will probably be a rambly incoherent mess.

First of, the suggestion to cycle carb sources to avoid overburdening the digestion with any particular antinutrient/irritant is great. So far I have been cycling potatoes, rice and oats and there were no sudden cortisol spikes like with wheat.

I thankfully already have most of the things you suggested and I was successful in lowering stress enough to sleep by taking Gelatine + Theanine + Magnesium acutely.

Physical relaxation I have a lot of trouble with, I was able to find some relaxation by going out into the nature, finding some space to lie down in the sun, far away from any passerbys. That's the only real method I found effective, but alas the circumstances for it are often not given. I can also do a bit of controlled breathing to increase CO2 but don't find it particularly relaxing. I think for the most part it's learned helplessness from not being in the physical state to be able to relax all the time.

Unfortunately overall it has gotten worse (not due to interventions, I think symptoms getting worse what led me to open this thread in the first place), at first I had to battle the insomnia a lot and while that improved bit by bit yesterday I ended up in a state of constant mental irritatableness where I hated everything. And despite falling asleep rather easily, I woke up with even deeper eye rings than usual. I have no idea what that means in terms of biochemistry, it was more than the usual Cortisol.

Hello,

I have been hypothyroid for about 22 years, the first 17 years I was so depressed that it just went by like a blur and I just assumed it was normal to have this little energy. Then the last 5 years I spend desperate trying to make a change, gradually overcame first social anxiety and then depression. But it wasn't until a few weeks ago I finally connected the dots and realized that I am legitimately hypothyroid.

I'm currently taking 120mg NDT/day and it has been very effective for the most part.

Unfortunately it seems the hypothyroidism also fucked up my digestion, if I eat the wrong thing I become cortisoid for roughly 6 hours, and thyroid doesn't fix it. This irritation also seems to cause allergies later, which then can cause an adrenaline cascade, which then causes insomnia.

Do I just need to wait for the thyroid to normalize the digestion? Is there any particular substance that helps get there faster? I've also been trying to find a method to end the adrenalinic metabolism so I can at least avoid the insomnia, but no such luck so far.

@LucH

Thanks, what does "stress hormone" specifically mean here? It doesn't sound related to the hormones that are usually called "stress hormones" like adrenalin or cortisol.

This is a topic that I always had trouble to understand because it seems thoroughly propagandized as a sex hormone and it is hard to find sources that do not make that base assumption.

• What is Estrogen on a fundamental level?
• If Estrogen is a toxin then why does the body produce it? Is it a just a byproduct/waste product or is it necessary for some processes?
• Is Estrogen significant for human dimorphism? Why does the female body produce so much more of it than men's body?
• What is the effect of too much estrogen?

I understand that the liver binds other substances to estrogen to get rid of it through the gut and that some bacteria in the gut reactivate the estrogens.

• Do all anti-estrogen substances work by eliminating these bacteria or are there other mechanisms to reduce estrogen?