@user73636 said in Low soluble fiber = leaky gut?: research indicates that when gut bacteria are starved of dietary fiber, they can begin to consume the protective mucus lining of the intestines. => Need a context and a study. Yes, this is accurate and refers to a well-known, seminal study on gut microbiome health. => A combination of host genetic susceptibility, low dietary fiber and intestinal bacteria exacerbate colitis. doi: 10.21203/rs.3.rs-2518251/v1 2023 Mar 13. Context: The "If You Don't Feed Them, They Eat You" Mechanism • The Problem: The mucus lining (largely composed of MUC2 glycoproteins) protects the intestinal epithelial cells from being directly attacked by bacteria. • The Mechanism: When gut bacteria are deprived of dietary fiber (their preferred food source), they turn to the next best source of nutrients: the carbohydrates in the protective colonic mucus layer. • The Result: This erosion of the mucus layer makes the intestinal lining thinner and significantly more vulnerable to inflammatory pathogens. • Significance: This finding provides a direct mechanism for why low-fiber, high-fat "Western diets" are associated with increased risk of ulcerative colitis, Inflammatory Bowel Disease (IBD), and metabolic disorders. Key Study "A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility" Authors: Desai et al. (Lead researchers include Eric Martens at the University of Michigan and Mahesh Desai). Journal: Cell (Nov 17, 2016). Comment (LucH): Not only when deprived but when some phyla take the lead. When you decide to correct and tend towards 30 g (1 oz.) fiber, you need to begin progressively and adapt yourself to transit. We need 4 colors to optimize the different effects.

@polba you are welcome It takes time and being consistent But you will feel much better and symptom free Just easy to digest stuff Nothing that irritates your digestion u

Now it's worse again, I think it is due to food. I am now keeping track of grocery store receipts and whether I feel better or worse afterwards to narrow down what's reducing symptoms and what's increasing it. It gets substantially worse if I eat too little so a elimination diet is off the table. Glycine helps a lot. Supposedly this is because during a state of sickness the body needs like 10-15g of Glycine daily to repair mucal barriers, gut lining, skin, etc, but can only produce 3g itself. It also generally increases the threshold for mast cell degranulation. I drink a few teaspoons per day dissolved in drinks.

Good thread. I am trying to swish with salt water to fix my breath problem. My Mom says my breath is "very sweet" and according to the internet its a sign of ketosis. Well that's about the only thing it can not be. I know it gets worse when drinking coffee.

@BearWithMe Any updates about this whole conundrum?

Update I'm feeling just fine again at rest like before taking the thiamine. Hooray!

@LucH said in Limit blue light with a software?: For what wavelength does lutein provide protection? Same question for blue light. => Lutein, zeaxanthin, anthocyanin. [image: 1772481782012-addf12df-1d7f-41e9-944c-194a4424c2d4-image.png] https://healthjade.net/what-is-lutein/ https://www.mdpi.com/2072-6643/13/9/3239#

You’d better listen to the signals of your body and accept them. Perhaps temporally though the body has memory (immune system). Perhaps not yet too late if you are very cautious with dairy. Nothing to do with lactose intolerance. 50 % intolerant with gluten are intolerant to milk. Mimicry. We don’t need dairy to get the appropriate amount of calcium even if it’s easier or if you like it. E.g. broccoli is very rich in available calcium. You don’t need 1200 mg calcium. The amount 550 or 850 mg Ca depends on how you deal with the acid-base balance (Na, Ca, K, Mg versus Phosphorus and Sulfur). To help balancing you’ll probably need: bisglycinate magnesium phophocalcium (+ calcium citrate when there is oxalate in veggies) potassium bicarbonate. I track my balance with cronometer.com (I’ve changed the targets). I repeat: you can’t force the body to accept sth when the intestinal linen are fragile / irritated. The sooner you accept it (100 % or it won’t never heal completely), the quicker you can get / optimize the tightness of the brush border of the stomach. I can give a link if interested, if you accept the fact you won’t heal “over the next 2 weeks”! To optimize the motility, get inform on MMC (interprandial motility). But you’ll probably need to heal the integrity and the thickness of the stomach linen before adding fibbers (with glutamine). A last advice: If you wait too long, you’ll get problem with the microbiota and perhaps / probably with candidiasis. There, no glutamine advisable or you’ll feed the beast. Act before you suffer from SIBO/ SIFO too much to tolerate what you can eat. Much more restrictive then. See my answer here to Samyo: Key information for SIBO / SIFO https://bioenergetic.forum/post/50601

@gg12 fix your liver, then your gut it appears you are not storing glycogen well, thus the stressed state, insomnia, intense cravings for carbs - quite similar effects to ketogenic diets/excessive fasting. Caffeine has a half-life of 5-6h, thus coffee before 2pm shouldnt interfere tremendously with sleep onset unless dealing with insufficient metabolic adaption to it (u can think of coffee putting your metabolic engines on 110% overdrive). It certainly will do you harm in the long term especially due to it ramping up FFA, Cortisol and perhaps exacerbating gut issues. Haidut has many posts regarding why prolonged Lipolysis = very bad Usually one adapts to coffee intake within a week, make sure to always side it with milk (since lactose-intolerant, mayb try gelatin), sugar and a meal (Theanine and B3 can help too). I like Affogatos. Keep somehwat of a steady glucose intake/well balanced meals thereafter. If you still crash by the end of the week try tea and focus on gut & liver health first Also consider Caffeine and CYP1A2 detox pathway as this, high estrogen and/or taking drugs/supplements that bind to the CYP enzyme (e.g. aspirin, quinolone, or phytonutrients like curcumin or polyphenols) might be another factor of heightened caffeine sensitivity / liver issues

@cookielemons I was eating a shit ton of them, probably 0.5 kg every evening, but yeah, I agree they were not my only issue back then

I have had the same issue with not just B vitamins but also any pro metabolic supplement like pyrucet. The trick is to both take the vitamins with lots of carbs and to also increase carb intake in the hours after, since your glucose oxidation will be ramped up and your blood sugar will plummet easier, leading to the fatigue you describe.

Another quick update. Just took a shower and removed a large quantity of earwax from my left ear. My left TMJ feels much better now, though not completely. I might go to an ENT in a month to get a professional ear cleaning. Even if you can hear, you could have earwax that is affecting TMJ symptoms.

Soon to be replaced by the Open AI brain chip. Zog planted right in your gray matter.

@sphagnum I think fact depletion is what they do on the low toxin forum

@happyhanneke said in Sudden dental issues/lack of saliva: @Jennifer I took some time to think about this. Thanks very much for the information. I am inclined to think it has nothing to do with hormone levels. The problematic part of menopause is years behind me and in those years I did have an increased amount of plaque. But I actually feel very good now. No more excess plaque. I used to have ulcerative colitis but that seems to have disappeared too with my menopause issues. I haven't had a flare up for years. But my nails are also brittle and break off easily. Therefore, I am going to the doctor to have a blood test done. If you have suggestions on what to specifically have tested I would like to know. I will ask her for sure to do thyroid panels. In the meantime I am slowly coming off cynomel. It didn't seem to do that much for me other than helping with my heart palpitations. I just want to see if I improve and if not I can always start again. You’re welcome. I’m glad you’re feeling good. Brittle nails, and any other connective tissue weakness, would relate back to thyroid/parathyroid gland function, as they are the main glands involved in calcium metabolism. The fact that you had heart palpitations, i.e., symptoms of adrenaline, would also indicate an underactive thyroid as the adrenals/adrenaline compensate for the thyroid when it’s not producing enough thyroid hormone. Personally, I don’t think blood tests are the most accurate diagnostic for thyroid function. Better are temps, including temps of extremities (feet, hands, nose and ears), taken first thing in the morning just after waking up, before eating, and 20–30 minutes after eating, pulse rate, achilles tendon reflex test and evaporation rate—total fluids consumed and eliminated via urine in a 24 hr period.

No proof with iodine on warf but ... I don't need a study to confirm the efficacity on every virus when it helps the immune system How effective is iodine as virucidal? (And by microbes, viruses, fungi and parasites) DOI: 10.1530/ERC-17-0515 Role of iodine metabolism in physiology and cancer. Endocr. Relat. Cancer. 2018 New research supports the exciting idea that I- participates as a protective antioxidant and can be oxidized to hypoiodite, a potent oxidant involved in the host defense against microorganisms. This was possibly the original role of I- in biological systems, before the appearance of TH in evolution. I- per se participates in its own regulation, and new evidence indicates that it may be antineoplastic, anti-proliferative and cytotoxic in human cancer. Alterations in the expression of I- transporters are associated with tumor development in a cancer-type-dependent manner. SARS-Cov-2 doi: 10.1371/journal.pone.0254341 The in vitro virucidal activity of intranasal Povidone-Iodine (PVP-I) has been demonstrated recently to reduce SARS-CoV-2 viral titers. EID (200 μg iodine/ml) after exposure for 60 and 90 seconds was compared to controls. In both cases, the viral titer was reduced by 99%. EID = Essential Iodine Drops. Influenza viruses Iodine, particularly in the form of povidone-iodine, is effective against influenza viruses by disrupting their structure and blocking their ability to attach to and enter host cells. How it works • Disrupts viral structure: Iodine makes structural changes to the viral coat by attacking key viral proteins • Blocks attachment: Iodine interferes with the hemagglutinin protein, preventing the virus from attaching to receptors on human cells. • Inhibits viral release: It also inhibits neuraminidase, a viral enzyme essential for releasing new virus particles from infected cells.

I think the most powerful tool for both SIBO and SIFO is MSM sulfur. This podcast by Dr Janel explains how well it has worked for antibiotic resistant sibo. Its cheap, safe and works. https://gijanel.com/gi-janel-one-video/