@anub Hi, Things to be taken into account. Don’t trust blood test with results if you’re borderline. Trust your feeling. How to manage is another problem. When modifying the dose, the connection between the brain and the thyroid requires 10 days to adapt. Get informed on deiodinase action too because you could lack some useful nutrients like iodine, magnesium, or event zinc if you don’t eat meat. If you eat carbs from cereals at 3 meals, you lack thiamine (B1). From Google AI: Thiamine (Vitamin B1) impacts dysautonomia by being essential for energy metabolism in nerve and muscle cells, and its deficiency can cause or mimic autonomic nervous system (ANS) dysfunction. Symptoms like fatigue, dizziness, and muscle weakness, seen in thiamine deficiency, also occur in dysautonomia. Correcting a thiamine deficiency with supplementation can lead to significant symptom relief in some dysautonomia patients See Elliot Overton (nutritionist) if you want confirmation on dysautonomia (3) and Dr. Antonio Constantini (neurologist). Note that some people aren’t suffering from what we call a nutrient deficiency but from a metabolic block. Dependent-B1 enzymes are blocked / inactivated due to some “stress factors” (see figure): chemical and environmental toxins, chronic inflammation and infection. Figure: Thiamine-dependent enzyme blocked in the metabolism [image: 1756106459772-thiamine-dependent-enzyme-blocked.png] KGDHC = α-ketoglutarate dehydrogenase complex = dependent-B1 enzymes. Credit: Elliot Overton (nutritionist) and Dr. Antonio Constantini (Italian neurologist) Warning: When taking high dose thiamine, there is a protocol to follow. There is interaction with other vitamins. For example taking 100 mg, then afterwards 500 mg of thiamine (the TTFD kind is advised for the brain penetration) will deplete the other cofactors involved in the assimilation of thiamine. Useful links Taking T3 and T4 synthetic supplement improves metabolism for a while https://mirzoune-ciboulette.forumactif.org/t2108-english-corner-taking-t3-and-t4-synthetic-supplement-improves-metabolism-for-a-while#30193 => Roles of deiodinases. Required nutrients for thyroid health. Time adaptation is required => "Since the body normally produces about 4 mcg of T3 in an hour, taking 10 or 20 mcg at once is unphysiological" - Ray Peat “With too much t3 the liver starts converting any T4 into reverse-t3”. - Ray Peat Brain Regions affected by thiamine deficiency How to Apply High-Dose Thiamine Protocols in Clinical Practice: Part 2 Practical Guidance https://www.youtube.com/watch?v=RFZUzS_xP9A EONutrition – Elliot OVERTON (nutritionist) (multiplex) – Part 2 – Video 2:04:02 This is the second of two lectures I gave to a group of medical/health professionals on the clinical application of high-dose vitamin B1. In this video I outline the difference between nutritional deficiency and the concept of "functional dependence". I then discuss the practical aspects of forming a protocol including: - Which form to use and why - How to dose for different conditions - When to use this therapy and when not to use this therapy - Managing patient side effects. *) 10 hallmarks of the video 0) 1.45”: recap of part 1. 07.059”: Basic Definitions 08.21”: Nutritional Deficiency 08.40”: High Calorie Malnutrition 11.12”: Functional Dependency 29.49”: Symptoms of B1 Deficiency 32.22”: Therapeutic Use of B1 34.40”: Forms of Thiamine Can You Use 45.05”: Peripheral Neuropathy 47.12”: Disulfide Derivatives 49.47”: Heavy Metal Chelating Ability *) The Art and Science of Mega-Dose Thiamine Lecture: Part 1 – Video 1:34:21 https://www.youtube.com/watch?v=-Uf1D2KdTn0 EONutrition – Elliot Overton (nutritionist)

I have not raised low cholesterol. This article has suggestions for lowering cholestrol and if by happenstance you are doing those things then you might consider changing. [image: 1755797949793-50fa52ed-319e-4712-8517-5807020cd15d-image-resized.png] Functional Foods for Cholesterol Management: A Review of the Mechanisms, Efficacy, and a Novel Cholesterol-Lowering Capacity Index (2025)

@Ilias-Ant Do you take any type of thyroid supplement? I can’t say for sure what’s going on, but if you are unable to tolerate sugar it is unlikely that your metabolism is thriving. Whatever kind of infection you have is likely impairing your metabolism, while also being a symptom of low metabolism. Someone with a high metabolic rate is not very susceptible to bacterial or fungal infection. In addition to thyroid supplementation, eating the carrot salad daily would probably beneficial.

@BeamsOfEnergy sorry I made a mistake it was meant to say acetazolamide and aspirin.

@winters2 said in Tocotrienols?: Do any of you take it? Isn’t it anti-peat, I’ve read that it suppresses cholesterol (same mechanism as statins) Chris Masterjohn knows a lot on cholesterol and takes / took 20-25 mg suppl a day to target what he wanted. Make a difference between RDA and pharmacological effects. RP has classified tocos as prometabolic (estrogen-antagonist when in excess) provided you take some points into account. If you're talking only about tocotrienols, I won't take them alone, except if in cure to target inflammation and optimize wealthy membrane. Only in cure then. Not at the same meal as vitamin K or other quinones. Useful links Assuming a typical intake of dietary PUFA, a vitamin E requirement ranging from 12 to 20 mg of RRR- -tocopherol/d can be calculated. The average westerner would need "only" 12-20 mg of natural vitamin E per day. The previous RDA has been changed since a majority of people were deficient. DOI:10.1017/S000711451500272X Vitamin E function and requirements in relation to PUFA. => Adjusting Vitamin E Needs with Unsaturated Oil Intake More info on Vit E (translator needed, in French): https://mirzoune-ciboulette.forumactif.org/t30-vitamine-e-plus-qu-une-vitamine#60 Excerpt 1: Most studies show a beginning of preventive efficiency at doses of 100 IU /d in degenerative diseases. Braking of oxidative stress which is underlying the phenomena of senescence and the appearance of all degenerative pathologies: cardiovascular, cancers, osteoarthritis, osteoporosis, presbyacousis, cataract, macular degeneration, Parkinson and Alzheimer's diseases, etc. Excerpt 2: Optimal contribution, without pathology, if under 40 years old: 100 IU per day. Contribution in case of supplementation in polyunsaturated fatty acids 100 IU per gram of EPA. - Therapeutic contribution: 400 - 500 IU every 5 days. Mg/ UI conversion: 100 mg = 150 IU. Personally, it’s 400 UI mixed toco every 3 days (+/ twice a week). 3x if inflammation. Note: High dose Vit K can interfere with Vit E metabolism. Not at the same time. Remind: Too much of a good thing is bad. Never take only one kind toco on a usual base. 2 tocos are required (functions are different).

@pittybitty My symptoms are consistent every day, bloating never really goes away, sometimes is a bit better, sometime a bit worse. I probably have candida overgrowth as well. My doc has ordered a lactulose breath test at the hospital, but I don’t feel comfortable to fast that long, so I would prefer to pay cash for a at home breath test for SIBO, but wondering if testing is worth or reliable at all to detect SIBO

Peat actually spoke out against limiting sugar in regards to Candida. I'm paraphrasing his arguments: Yes, Candida can ferment sugars into ethanol, however small amounts of ethanol is benign, and if you starve them of sugar the Candida will spread and attack your cells. And Duboe showed that if you starve these yeasts that are just happily making some ethanol out of the sugar, when they don't get sugar, they start... sending out pseudopods, or pseudohyphae, I think he calls them, which are invasive filaments that will sink into the intestine looking for sugar. And that's the point at which they can actually travel through your intestine and get into your systemic tissues looking for more glucose. So really... having sugar in your diet, if you have a fair infestation of yeast, for some reason, in your intestine, sugar is a defensive means while you're trying to figure out how to get rid of the yeast, which carrots will usually do fairly quickly. So essentially you want a high sugar diet to keep the yeast happy and the carrot salad to get rid of it while it is happy.

My pleasure, @GRay.

@LucH thank you brother. I really appreciate the assistance

@pittybitty said in Serotonergic slumps at night: Are you sure? Make a google search with: blocking noradrenaline led to fine dreams

waking up at night is usually caused by low blood sugar, which triggers cortisol and adrenaline to raise blood sugar by breaking down glycogen and muscle for amino acids to convert to glucose via gluconeogenesis. things that help with this: eat some ice cream before bed (good ingredients, haagen dazs vanilla etc.) cyproheptadine (1-4mg a couple hours before bed. you can get it from idealabs) famotidine (helps spare glycogen in the liver which will keep blood sugar stable overnight) progesterone (popcorn kernel sized dollop of kenogen progest-e rubbed into gums before bed. progesterone absolutely nukes cortisol and helps a lot with sleep, and metabolism in general) i have had this exact problem and routinely do one or more of these things every night and have great sleep now.

@Milk-Destroyer I wonder if you had taken an antibiotic close to the time you took citric acid or citric acid-containing substance. I'm not sure which antibiotic I took at that time, whether it's erithromycin or tetracycline, but it's one which would cause bacteria into cell wall deficient bacteria, and in combination with citric acid, would lead to growth of microbes closer to fungal forms. But it made me very sick and I had to use my own protocol of Carbogen and turpentine and artemisia annual tincture to counter it. It was successful but it was luck that this protocol worked. But at that time, I didn't want to check into an ER because a worse outcome would be likely during the COVID hoaxing years.

thanks. I am listening to it now (It is raining). Here are the timestamps: 00:00 Intro 02:12 What Is Roger Aiming to Accomplish? 03:13 The 8 Pillars of Health 08:58 Story of Henry: A Fungal Lung Disease Patient 20:25 Why Our Mitochondria Need Sunlight 27:31 Sunlight and Viruses: Impact on COVID-19 29:45 Vitamin D and Lower Risk in COVID Patients 33:40 Benefits of Using Infrared Light Devices 47:35 Could More Sunlight Help You Live Longer? 51:05 Does the Sun Really Cause Melanoma? 54:22 Are Humans Meant to Live Outside? 57:16 Is It Worth Wearing an Infrared Light Mask? 59:16 How to Get Infrared Light on a Cloudy Day 01:07:59 Optimal Time of Day to Get Sunlight 01:09:19 Circadian Rhythm and Light Exposure 01:11:13 Benefits of SAD Light Therapy 01:12:47 Can Looking Through a Window Help Circadian Rhythm? 01:14:56 Why Should We Avoid Bright Screens at Night? 01:17:16 Should the Bedroom Be Completely Dark at Night? 01:19:08 Do Vitamin D Supplements Work? 01:20:59 Possible Consequences of Vitamin D Overdose 01:21:47 The Role of Vitamin D in the Body 01:23:45 Do Cravings Signal Nutrient Deficiencies? 01:25:20 Water’s Role in the Body 01:27:05 Interferons and the Innate Immune System 01:32:37 Importance of Hydration for Fighting Infections 01:34:20 Should We Use Hot and Cold Therapy Together? 01:35:55 Impact of Tree Aromas on Immunity 01:38:29 Do Indoor CO₂ Levels Matter? 01:39:15 How Can We Optimize Indoor Air Quality? 01:40:22 Faith as a Way to Deal With Stress and Anxiety 01:42:27 Conditional vs. Unconditional Forgiveness and Stress 01:45:40 Are People Who Believe in God Generally Healthier? 01:47:19 Roger’s Experience Witnessing Death 01:48:59 A Miraculous Story: Anoxic Brain Injury Recovery 01:59:02 Should Hospital Patients Be Taken Outside? 01:59:42 Are Melatonin Supplements Good for Sleep? 02:00:30 Side Effects of Melatonin Supplements

@alex155 said in Serotonin question: for those who are afraid of tryptophan and serotonin, this study about B. subtilis will be interesting, what bacteria should be avoided, but I assure you that you won't even be able to take a shit without serotonin... and for now I will continue to experiment on myself B.subtilis has shown to be capable of secreting polymyxin, difficidin, subtilin, and mycobacillin. [image: 1753998005826-20210426_190216.jpg] https://microchemlab.com/microorganisms/bacillus-subtilis/ thus reducing overall unwanted bacteria.

@lobotomize-me said in need advice: taurine I'd stop taking taurine, but not abruptly, every other day. Taurine is used for making bile. We want to avoid stagnation. Afterwards cut the dose to max 500 mg, once a day. And see how you react (adapt the posology). Note that 10 % fat is not enough, if you want to avoid problems with hormones and thermoregulation. I'd target 20% fat. useful info: Taurine plays a crucial role in bile production by acting as a substrate for the formation of bile salts. These bile salts, formed by conjugating bile acids with taurine or glycine, are essential for emulsifying fats and aiding in their digestion and absorption in the small intestine. The liver synthesizes bile acids, which are then conjugated with taurine and glycine, and stored in the gallbladder. Upon ingestion of fatty foods, these bile salts are released into the intestine, where they help break down fats.