Progesterone can only do good, especially after taking hellacious finasteride, I would be grateful my body can produce any amount and leave it alone. For men, in the short term progesterone's benefits might not be obvious, but in the medium and long term it is spectacular. What to definitely avoid and keep low is estrogen, which progesterone is good at doing.

@CrumblingCookie thanks for your response. I was thinking it might be fungal, but due to the fact, I have bangs and its not on my forehead and concentrated around my jaw, I am certain it’s hormonal. That’s why spironolactone , metformin, and inositol reduce it. I agree with mold I will look into that. I’m also looking into getting a gut microbiome and Dutch test. My partner also recommended taking iodine. I’ll give you feedback once I have more results. In the middle of my 30 day cleanse my cheek acne has reduced, but I still have some jaw acne so hopefully that’s a sign that it’s a combination of hormonal and gut so time will tell, thank you!

@alfredoolivas agreed! You want to keep a steady flow of dhea and preg. Otherwise you can take it standalone assuming you're not taking an outrageous amount 10 times a day. Taking it for years, I never experienced suppression

@engineer Reporting back on this: CrumblingCookie said: Topical application on the lower abdomen reportedly does not bring about these tense and stressful cardiovascular sensations. Lower abdomen application consistently caused the same. Only more delayedly after a few hours in comparison to the rather fast onset by application on the chest/thorax. Surprisingly, however, it showed that increasing thyroid hormones alleviated this dis-ease. Assumedly and in line with many thoughts before this the extra DHT administration spotlights basic metabolic insufficiencies. Wouldn't limit this to thyroid hormones at all but expand the need for them into a wider picture of metabolic disturbances (which supplemental thyroid hormones may or may not cover-up in part). I.e. no shortcut to better health but more like a possibly powerful booster to override adverse effects from other supps or habits when already in good metabolic health IMO.

@sunsunsun in case you don't already know, on the old rp forum Haidut said it can be a result of extreme hypothyroidism, over-training or over-excercising

@peatqqq maybe switch the Apple juice for orange juice if it appeals to you. Ray Peat used to caution about mold in (store bought) apple juice. And mold can cause or exacerbate all kinds of symptoms/conditions. I guess if you can juice the apples yourself you'd know that won't be a problem.

would preg/dhea and proviron be interesting?

@jakethesnake did you make sure to cook the mushrooms well?

Thats pretty much how I see it too. If a supplement already works in its regular form, I don't really see the need to make it nano.

@Samyo pretty sure malessezia uses fat too maybe try s. boulardii to outcompete other yeasts

@engineer have you seen this?: https://raypeat.com/articles/articles/rosacea-inflammation-aging.shtml Maybe tetracycline would help, or more simply, a raw carrot a day, or an overthecounter anti microbial like bismuth subsalicylate (kaopectate)

@lobotomize said: @Alsulaimani take pregnan its a neurosteroid and gaba a agonist . cycle it so to not kardashian yourself Was going to say that this a job for high quality pregnenolone. @alsulaimani , most of the pregnenolone on the market is reported to be impure junk that won't work as expected. One of the precious few products we can recommend with a degree of confidence is from Haidut's store. You may also want to try cycling thru a few magnesium forms till you find one that hits you the right way. For myself the Mag sulfate, bicarbonate, hydroxide and chloride forms make me care much less about negative comments from people, but there are limits. Small doses throughout the day work well for me. Calcium is calming for some so maybe take a tiny bit along with your Mag for proper mineral balance. Androsterone in low-mid doses makes me very outspoken, that may not be good in a retail environment. It does feel good though. Haidut's 11-keto-DHT product reminds me of a stronger pregnenolone and i can even feel it lowering the cortisol response of too much morning coffee on an empty stomach. But personally i'd start on Pregnenolone and Mag and test that protocol for a few weeks. Let us know how it works out.

I think it has to do with bile flow issues /cholestasis. IIRC a progesterone metabolite is implicated in pregnancy induced cholestasis. "Significantly less hepatic bile partitioned into the gallbladder in progesterone-treated than in control animals." https://pmc.ncbi.nlm.nih.gov/articles/PMC1191632/ Ive had similar issues in the past when taking pregnenolone and progesterone. Id try some things that help with cholestasis like TUDCA, gentian or cascara.

@ZackVegas https://www.meforum.org/middle-east-quarterly/why-arabs-lose-wars

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@engineer Fair, lol about the creatine

Replying to an old thread on off chance it might help someone. Have had tinnitus on and off for months. It was never fully gone in that time. I assumed it was caused by endotoxin (diet has been mixed at best lately) and/or higher than usual aspirin use. I took 250mg of niacinamide earlier and the tinnitus is now completely gone. It's a shock to not even hear it as a background hum, which shows me just how constant it's been these past months. Ray gave the advice years ago that niacinamide can treat it. Worth trying.

Yes, actually. At the beginning of the year, I had a scaly growth on my scalp. I went to a skin cancer clinic to get it checked out, and it was confirmed as a seborrheic keratosis. It was suggested to me by the doctor that it was best to leave it alone, or alternatively I could get electrocautery with the risk of a permanent bald spot. I was unsatisfied with those options so I did some Googling. The solution I found was diclofenac gel. It's an NSAID sold as a topical solution for muscle pains, arthritis, etc. The product I used is sold as "Voltaren Pain Relief Gel 12 Hourly" in Australia, which is 23.2mg/g diclofenac gel (or 2.32%). It's generally suggested to use a strength between 1% and 3% for seborrheic keratosis. I applied it every morning for about 6 weeks and it started to flake off after a few weeks, leaving brand new skin underneath. Completely gone. I'm pretty thrilled because I was told to live with it for the rest of my life. It cost me literally $12 to get rid of it. I hope it helps you too. -- Here's some literature to support it: Diclofenac gel may be a new treatment option for seborrheic keratosis: https://pmc.ncbi.nlm.nih.gov/articles/PMC4886602/ Comparative evaluation of topical diclofenac sodium versus topical ibuprofen in the treatment of seborrheic keratosis https://pubmed.ncbi.nlm.nih.gov/33022801/ Novel Research Regarding Topical Use of Diclofenac in Dermatology—Non-Clinical and Clinical Data https://www.mdpi.com/2218-0532/93/3/34 Comparative study between Diclofenac 3% Cream and 17% Salicylic acid + 2.5% 5 fluorouracil cream in the treatment of Seborrheic Keratosis https://ijced.org/archive/volume/12/issue/1/article/26344/pdf

@alfredoolivas Sure, although my appetite is already naturally pretty low, so the effects might not be that noticeable for me.