@GRay said in mk4 dosing?: isn't only the k1 that effect clotting? K1 and K2MK7 too affect clotting. For Chris Masterjohn, MK7 would even be better. Chris Masterjohn : « The ultimate vitamin K2 resource »). https://chrismasterjohnphd.com/blog/2016/12/09/the-ultimate-vitamin-k2-resource/ Excerpt 1: There is reason to think MK-7 would be better at supporting blood clotting. “MK-7 is not just three times better than K1 at reaching bone; it’s also five times better at supporting blood clotting (Schurgers, 2007). This may be because the greater fat-solubility of MK-7 makes it hold on more tightly to the membranes within liver cells, making it stay active in the liver much longer rather than being released and broken down (Shearer, 2008). The liver is where clotting proteins are made, so more extended activity in the liver would explain why MK-7 could better support blood clotting. If this is correct, other long-chain MKs such as MK-8 and MK-9 probably share this property as well.” Additional comment: The risk of improper clot formation is increased in cases of low vitamin K levels. Vitamin K (VK) does not cause or dissolve blood clots. However, VK enhances the function of both these systems. VK1 can therefore be seen as a facilitator: Procoagulant factors are VK-dependent. Remind that platelet formation requires 10-12 days after taking aspirin, whatever the dose is (baby or adult caps).

@engineer interesting I'd like to see that study. Georgi cured cancer by giving mice high doses of biotin (HED ~200mg), other b vitamins and aspirin. And there's also a few long term studies on very high dose biotin for MS and i don't recall that they saw any increased level of severe side effects (like cancer).

@jamezb46 I remember 18 nor T, but were we talking about a different steroid? Wasn't 3beta-hydroxy-pregna-1(10),4,9(11)-trien-2-one mentioned by Patrick Arnold in a phone call to Ray Peat?

@sunsunsun bruhnem like 10 min boil milk then add oats lower geat stire for like 5 min

Fat loss has absolutely nothing to do with metabolic efficiency. When the body has enough nutrients it will spend some of that nutrients on building new fat cells. This can only be stopped by inhibiting mTOR activation, usually through APMK, which naturally happens during fasting and during heavy exercise. The threshold is high, passively burning more energy will not suddenly spike APMK.

@zorba990 kind of an amazing find as for the issue you are talking about maybe you could heal it with a moggy silicon intake. peaty diet is probably deficient in it.

@16characterstwas I am going to take a few days off and then do the co2 bath again. see what happens. I will keep it to 1 hour or less next time.

@lobotomize haha

@DavidPS said in The Top 5 Can’t-Miss Sport Supplements: Nitrates, found in beetroot juice Nitrates, found in beetroot juice. they interfere with cytochrome c oxidase no?

@Peatful my dog actually grew a lipoma of some sort when I added bluebonnet brewer's yeast powder to her diet.

Maybe the problem's above your complaint @gg12 . Hydrochloric acid.

@gg12 Does coffee deplete calcium ? Don’t think so Why is my sleep worse on days I drink coffee / it’s hard to fall asleep even if I drink it at 9am. I almost feel like the effects last for a day or two. Try less strong coffee or decaf (with cream and sugar.) And in small amounts. Then work your way up. I feel like it makes my metabolism too fast so I franticly eat starch slop to calm down the starvation. But this just makes issues worse in the long term. Have it with cream and sugar. makes all the difference in the world. Should I force a cup of coffee everyday and hope I adapt? I have SIBO , lactose intolerance, poor liver, bad liver glycogen etc just looking to get things up to speed again. No, forcing doesn’t work. But it does help with those and alot of things, not just because of the caffeine but also because of the nutrients, chlorogenic acid, etc. So start with decaf (still has some beneficial caffeine ) and in smaller amounts, then work your way up. Add some cream and sugar to balance out the caffeine and other components.

Or the other way around. Better to keep so-called soluble fibre low, to prevent LG

@gg12 what @awawat said. Also other things to try: Goat milk; Ultra pasteurized (UP) milk which is often labeled UHT (Ultra High Temperature) milk; Buttermilk (tastes like unsweetened kefir) Try whichever appeals to you and whenever you feel like having some, then work your way up. Sweetened condensed milk is another great option. Good luck

@BearWithMe said in Mysterious gallbladder disease - can't digest fat for no apparent reason: salt might be necessary for stomach HCL production I don't add any salt now and cook food myself with no salt. My blood levels of CL are always showing in higher range. If I add salt my stomach feels irrtated or inflamed , it rather hinders stomach HCL production. But a bit of pickles with a teaspoon of brine can be very helpful occasionally .

@user73636 said in Dietary calcium does not affect pyruvate dehydrogenase?: Your body maintains a very strict range of calcium in your blood regardless of how much you eat. Because of this: The quesiton is how does PTH (affected by dietary calcium) affect PDH.

@polba you are welcome It takes time and being consistent But you will feel much better and symptom free Just easy to digest stuff Nothing that irritates your digestion u