yeah, I doubt it’s that but my results are quite weird… my body cannot utilize B6 for some reason

@Peater0921
Besides surgery just adds to the physical stress on the body and would probably lead to more

I would first make sure I’ve eliminated pufa from my diet, because it seems to increase them

Someone asked ray..

Post in thread 'Ray Peat Email Advice Depository'
https://lowtoxinforum.com/threads/ray-peat-email-advice-depository.1035/post-389201

Me: Topically I been adding Dhea and Progesterone on the mole for about a week now but havent seen any change.
How long did you do it to see a change?

RP: I’ve never applied anything directly to a mole, because of the danger of causing irritation that could cause cancerization. When I have put progesterone or DHEA (dissolved in vitamin E) on the skin about an inch away from a mole, I have seen changes the next day, with steady shrinking during a week or 10 days. Sometimes I have just increased my dose of T3, to keep my daytime temperature at least normal, and it increase my resting pulse rate to about 95 beats per minute. I think I have accelerated the dissappearance of some moles by soaking in a bath containing epsom salts, baking soda, and salt.

just buy aspirin and glycine

@SanguisEtAqua It could be a low energy problem and it could also be a ‘too much technology’ problem. I know when I’m too attached to my phone I’ve got very little creativity. Playing with children on the other hand can be just plain boring if it’s not your interest. I adore my toddler, but I’d rather stare at the roof than play with other people’s kids.

@16characterstwas @Tarzan17 &this

Post in thread 'Ray Peat Email Advice Depository'
https://lowtoxinforum.com/threads/ray-peat-email-advice-depository.1035/post-882797

Milk and sugar, custard with a minimum of egg (only
natural vanilla for flavor), eggs, meat, and sweet ripe orange juice, are
the easy things to digest. Even small amounts of plant material can cause
inflammation for some people".

@GRay said in mk4 dosing?:

egg shell powder

egg shell powder is essentially calcium carbonate (+ useful nutrients).
We need P to absorb Ca. But not at a meal with HD meat (acid pH 3-4).
I won't take Ca supplement if my acid-base balance is fine (K Mg Ca) and P in the lines.
I target 850 mg Ca. When I'm under the target like today (450 mg), I add phospho'cal 1.6 g, + 1 half dose Mg bisglycinate to reach my level (+/ 420 mg Mg) (1/2 of 3 g) + 1 big dose potassium bicarbonate (3.2 g).
So, no need to be over 550 mg Ca (like the hunter-gatherer tribes in the African savannah.
I do / proceed like the reed: Bend (flexibility) but I do not break 😉

I've only gotten weird gut issues with progesterone when taking 30mg+ topical in ethanol per day. And even then, it sorts itself out within 4 to 6 hours.

Small doses <12mg/day or so don't have this effect on me.

@CrumblingCookie

LOL!

I've been observing my stools. They look rather pale and I may not be forming stools with the help of bile. And I have skin itching, and this could be from using Emeramide to detox lead. I suspect it's because the lack of bile is keeping the lead from being excreted thru the fecal route, and it is using my skin as an alternate route for excretion. Perhaps the urinary route can handle only so much.

To continue on the topic @randomname brought up

Post in thread 'Ray Peat Email Advice Depository'
https://lowtoxinforum.com/threads/ray-peat-email-advice-depository.1035/post-875276

Q: Thank you Dr.Peat
One more question

You talked about the negative effects of darkness.
So, I was wondering. If someone is a night owl and he spends his night time with a good incandescent light turned on, drinking and eating some sugary stuff, calcium, sodium etc - would the negative effects of darkness be diminished in any way?

RP: Yes, even intermittent bright light can reduce the damage.

low fat high carb diet probably.

I've overdone thyroid before and the nerve-damage type symptoms will go away and you will recover.
Some thiamine, niacinamide, and a couple months of decent eating and rest and you should be back to normal.

@jamezb46 do you take gelatin (oxtail, wings, shanks, jello, Great Lakes gelatin,..) along with the meat to help balance out the aminos?

@happyhanneke ok . I see. Then maybe some brewers’ yeast sprinkled on morning cereal and or in soup salad or stews will help add needed b vitamins in a naturally concentrated and tasty way. It can also add flavor microwaved popcorn. I like the solgar brand.
5daa17ac-f6d6-4705-9042-d2c2151845c4-image.jpeg

@Mauritio so, I actually have one version of that, and tried that in camphosal, and I couldn't tell what disolved or didn't, as it also has niacinamide in it... I didn't see any significant improvement in my tongue, but it could've been due to the small amount I used as I was nervous about it actually working before I used all my camphosal (alternatively, could camphosal expire after 8 months after the date on the bottle?)...

I wonder if "cuprous nicotinic acid" dissolves in camphosal, just like regular copper.

@CrumblingCookie said

This means that stimulating synthesis of CoA and CoA-Ac will strongly increase histone acetylation. Which should be a complement (or beginner's alternative) to inhibiting histone deacetylation (HDACi).

👍 https://pmc.ncbi.nlm.nih.gov/articles/PMC3377114/

decreased acetylation of these proteins is associated with an impaired DNA damage response, decreased locomotor function and decreased survival. Decreased protein acetylation and the concurrent phenotypes are partly rescued by pantethine and HDAC inhibitors

Wrt to cancer there actually seems to be some specific merit to inhibiting CoA availability in lung and breast cancers, where the SMVT appears significantly upregulated, effectively supplying the tumorous cells with increased supplies of biotin (and pantothenic acid), promoting cell survival and proliferation (which we would like to see more of in non-tumorous but of course not in tumorous tissues).

👌

@yzzy I didn't want to assume their gender

@DakotaWorrell You will never, ever be able to "figure this out". We all have different diet histories, activity levels, etc.

I think that as long as you're staying well under known toxic doses, you feel good, and you have some degree of balance between nutrients that are known to interact (ex. vitamin d, k,a; phosphorous:calcium, protein:carbs), that's about the best you can do.

thyroid hormone is dosed and micrograms and iirc is sensitive to light

@PrinceTrebata yes I remember ray saying that. I also recall that he said a small amount of progesterone combined with a little dhea (for example 8mg p4 with one mg dhea) would have a similar effect as pregnenolone would have:

https://lowtoxinforum.com/threads/ray-peat-email-advice-depository.1035/page-47

@Meursault consider the possibility the cause

@Meursault said in Wisdom tooth causing infection:

@Chud
the dentist suspected the infection had started 2 months ago which was a time when I was suffering from a build-up of the effects of chronic stress and inflammation. Cascara basically fixed my digestive issues and so I'll try that again along with carrot salad. one thing I am concerned about is the antibiotic treatment worsening gut health in some way. One thing I have noticed on the antibiotics is a very bad histamine response. I already had an issue with this and cyproheptadine makes it better but hasn't fixed the root cause. I suspect impaired liver function and lack of bowel movements, endotoxin as you mentioned is implicated in this. Read that Ray peat recommended taking sugar with amoxicillin to someone who had similar reaction as it is an anti-histamine. I'll try everything you mentioned, I imagine a lot of it will be important in maintaining a lack of any bacteria exposure to the gums that were affected once done with the antibiotics

Consider that “worsening gut health“ might be that the amox standard dosage, if that’s what you’re taking, is too high/too toxic.