@Gardner well, I think there’s a narrative or belief that competitive sports do these things, but really in all but a handful of cases the bulk of competitive sporting leads to metabolic dysfunction. It’s over-exercise, coupled with under-nourishment or incorrect nourishment, typically wrapped in a mythos of sacrifice, (for the team, for the sport, for the coach, etc).

Played for fun, maybe with friends, sure, I could see it being positive socially, but even then, running, depleting glycogen stores, illiciting cortisol response, upregulating lypolisis, hyperventilation. The negatives seem to vastly outweigh the positives, (of course this is just my experience/opinion). Done habitually, these conditions become chronic.

Me personally, I’d say I encountered thyroid dysfunction, excessive cortisol, malnourishment, an unhealthy exercise habit, body dysmorphia, estrogen dominance, hair loss, brain injury, depression, drug dependence,IBS, etc, (general symptoms of low metabolism). I think my experience is not unique. It seems like most professional athletes suffer in the same ways, (whether it’s the weight gain of retired athletes, drug addiction, alcoholism, symptoms of serotonin overload - antisocial behavior, poor sleep/recovery). All just signs of poor metabolic function.

@Androsclerozat skipjack tuna reliably gives me intense feelings of wellness after having a can after not having it for awhile.

good point on pasta, I had 250g for two days in a row, I didn't know it has such protein amount

I started with parboiled rice, it is middle point of brown and white rice, has more nutrients than white rice but still removed fibre part in brown rice, seems like nice middle ground.

I am considering pea protein powder as maybe it can provide benefits of aminos after exercises without too much negatifś

your diet is similar to mine except I don't add any fats that aren't present in the natural food

I have cooked greens on rice and some eggshell powder also

@Androsclerozat said in My suicidal experience with potatoes solanine driven depression:

@random writing ... makes me less logical, it stops the enumeration thought and helps me move on to the next idea and not get lost into details

Possible, yet it let others assume what you mean or the feeling you're trying to convey, and that can reduce understanding, I suggest it's better for the person to use the words that best correspond to what they think/feel rather than "..." for optimal understanding

@GreekDemiGod I guess having a reverse t3 tested would be even more helpful.

Some updates:

Clenbuterol (10–40 mcg) was unfortunately disappointing. It caused unpleasant heart palpitations even with minimal physical exertion. A further reduction in dosage and a different context might be necessary.
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Initial experiments with 20 mg Bromantane: minimally stimulating (increased dark circles under the eyes and slight facial muscle tension), auditory enhancement (music experience felt more immersive), increased thought flow (more associations and memory retrieval), enhanced affectivity and mood improvement. Later on, strong fatigue occurred (though not sure due to bromantane, as I had little sleep the previous night), brain fog.
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Upcoming experiments are planned with galantamine, TAK-653, sulbutiamine, and trans-Isrib.
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Ongoing experiments also include a change in the roa for 2C-B from oral to intranasal. I hope for improved context-sensitive kinetics (faster onset/peak/offset), increased comfort, and reduced body load
(maybe even s.c. or i.m., will see)

@GreekDemiGod thx

@adrn100k Maybe testing again would have a different reading of TSH.

How’s the temp and pulse tho?

@alfredoolivas said in Pro Metabolic Substances Tier List:

@Hando-Jin thanks for sharing.

Thyroid doesn’t stimulate appetite for me and it might even lower appetite for me, if anything. But not significantly. I already am taking 50mg of exemestane a day, I like it.

Thyroid increases GLP-1, which is why maybe it lowers appetite.

Interesting.

I've also found gelatin to be a really good suppresser of hunger cravings.

Main issues for a while have been feeling ill on a regular basis. It seems to be lodged close to my tonsils and think it's leading to fatigue and low mood. In the UK it's not common for the NHS to swab your throat and test it, they just love to prescribe antibiotics based on symptoms or tell you to rest if you have a virus. It's quite frustrating. I know Ray was quite an advocate for antibiotic use but I think the potential downsides are significant and feel like my immunity went downhill last year when I did two courses of antibiotics, having never done any my whole adult life.

I did a blood test on Tuesday so should get results soon:
https://lolahealth.co/products/ultimate?variant=45501879713944

I'll then be doing a consultation with a private doctor and want to discuss these issues as well as potentially having an intro to a TRT clinic.

I did a mycotoxin test last year which came up high in ochratoxin so I've been trying to detox that via home farinfrared sauna and activated charcoal plus bentonite clay.

@RePeat said in Vanquishing reflux and depression:

I wonder if there are natural sources of l. Reuteri.

I've since learned that L. Reuteri must be present in some way in raw milk and saucisson (dried sausage that we have in France) but more importantly it is present in sourdough, what would be a very common source for most people at least here in Europe.
I bought into a lot of peaty habits but it never felt right to completely exclude cereals from the diet-- I still consume bread regularly, mostly whole bread fermented with natural sourdough. This could help!

On the topic of depression, there seems to be another of these "simple trick" that's easy to try and might help: chewing gum. I indeed found out that chewing gum was notably associated with mood uplifting and relieving symptoms of depression, and also with ADHD.

At 2 weeks, the score of state anxiety was significantly lower in the intervention group than the control group. The intervention participants’ scores of depression-dejection, fatigue and confusion in POMS were better than the control group scores. Mental fatigue were also relieved after the intervention. At 4 weeks, there were no significant differences between both groups.

--- PMID: 21866229

Logistic regression analyses showed that the effects of chewing gum on stress and health remained significant when [...] confounding factors were controlled for. These results suggest that chewing gum may be a simple way of preventing stress and the negative health outcomes that are often associated with it.

--- https://doi.org/10.1002/smi.1272

The most beneficial effect of chewing gum was observed on the gastrointestinal symptoms, e.g. loss of appetite, and flatulence among others. These results indicate that chewing gum may not be directly effective on depressed mood; however, it may reduce the symptoms originating from depression.

--- https://doi.org/10.1016/j.appet.2013.02.002

According to the preliminary results in the present study, intervention of gum chewing for patients with depression may be of some roles in maintaining their mental health.

--- https://doi.org/10.2974/kmj.63.13

Other results are less optimistic but still significant:

Perceived stress decreased as a function of the amount of gum chewed. The chewing gum condition was also associated with a decrease in not getting enough academic work done. There were no significant effects of chewing gum on mental health outcomes.

--- https://doi.org/10.1016/j.appet.2012.02.054

Rate of chewing and subjective force of chewing did not alter mood but had some limited effects on attention. Chewing gum during the workday was associated with higher productivity and fewer cognitive problems, raised cortisol levels in the morning, and did not affect heart rate. The results emphasise that chewing gum can attenuate reductions in alertness, suggesting that chewing gum enhances worker performance.

--- https://doi.org/10.1155/2015/654806

You might just try it out!

@nicemushroom17 Not mine. This guy has no idea about me. I think he did raised seat cycling.

@idealabsrat i tried this last night and when i went to cook the rice after rinsing the water would not evaporate. my rice essentially turned into porridge slop. i boiled it for one hour, rinsed the rice in a strainer, then brought to a boil with a bit of water and cooked on low heat. not sure what i'm doing wrong or if this is the proper texture when cooking it this way

@Hearthfire

Ya, that what I’m doing

@PrinceTrebata Transdermally 50mg most of the time because it is 1ml of my solution / a full dropper.
I get effects from less than that but sub 5mg might be too little for topical.

@Mr-X dang I forgot *:D

I definitely have clearer/worsened skin depending on when I have good metabolism vs stress.

I think haidut posted a study saying a single 40mg dose of propranolol before doing something you find fearful can help eliminate the fear response completely for the next time you have to do it, forever.

found the post:
https://lowtoxinforum.com/threads/blocking-stress-adrenaline-just-once-cures-ptsd-and-maybe-any-mental-disorder.28622/

40mg propranolol 1 hour before the fearful event and then get a good nights sleep afterwards.

For the 2021-2023 NHANES data, in order to remove TRT users, I screened out those with testosterone over 600 who also had LH below reference range. Apparently TRT lowers LH and FSH to near zero. I also removed some data that was probably in error.

So average testosterone in 2021-2023 was 451 ng/dl - no major difference from 2015-2016's average of 459 ng/dl.

2021-2023:
20-24: 536
25-29: 464
30-34: 476
35-39: 440

2015-2016:
20-24: 535
25-29: 556
30-34: 461
35-39: 466

2011-2012
20-24: 468
25-29: 438
30-34: 435
35-39: 392

2003-2004
20-24: 673
25-29: 537
30-34: 541
35-39: 589