@rope said in Cynoplus sources in US: @Ecstatic_Hamster Let us know if it gets delivered They said they are shipping soon. I shall.

@sunsunsun said in Switch to OLED monitors for less blue light at night: @engineer which tandem oled monitors? https://tftcentral.co.uk/news/asus-unveil-the-rog-swift-pg27ucwm-with-a-27-4k-tandem-woled-panel-and-rgb-stripe-pixel-layout

@PissBoy the one from Keith Littlewood is supposed to be good

@alfredoolivas how did the end product work out for you? Did it seem like it worked?

@hwisdom why wouldn't you just put androsterone on your balls? Preg doesn't directly hit the backdoor pathway

@alfredoolivas Becuase if adding mitolipin to a solution of HCL causes the phosphatidylcholine to break down that suggests that the same thing would happen when we eat it.

Another update, this one’s pretty interesting… I’m still plugging away with glycine, (1 tsp at each meal) and it’s been the holidays, so I’ve had some beer and some bourbon, (some PUFA or otherwise “unhealthy” choices here or there,(nuts, salad, things that other people would consider healthy ironically…)). I decided to do a finger prick the other day and an hour after coffee on an empty stomach, and landed a 94! This is kinda amazing. Glycine has essentially perfected my blood sugar! Two other interesting notes: one, I’m up four pounds in weight, but have dropped from 34-32” waist. Two, I’ve weight trained since a teen, (in my mid forties now) but took a year or so off when I couldn’t figure out how to train without a stress response. I’ve been back training regularly 4 days a week for a few months now, and have struggled with 230lbs on the bench press, and anything over 100 standing shoulder press. This week I benched 250, and shoulder pressed 130! Not Olympian numbers, but really amazing considering where I was just a few months ago.

@lobotomize The difference is in isotopes, not sucrose content. Though beet sugar does seem slightly less sweet.

You are awesome pannacotta

Pansterone separated again due to cold snap and heater not being on Time to get that ridiculous roller mixer thing

@engineer to touch . it is cosmic beach sand from an asteroid anyone notice asteroid has the word steroid innit?

New product is ready, will announce on a separate thread soon.

@sunsunsun true lol

@jamezb46 the idea was that even though bakuchiol itself doesn't aromatize to estrogen, its estrogenic effects would essentially take the place of existing estrogen aromatized from different sources. The purpose of the AI would be to reduce aromatized estrogen elsewhere so that the bakuchiol in addition to existing hormones doesn't cause hyperestrogenic symptoms. Of course, this wouldn't be viable if bakuchiol is so estrogenic that an effective dose would exhibit an estrogenic effect greater than what would already be present. I also thought that DHEA became estrogenic at higher doses if there is already of lot of it present. Is that not true? Also, it's disappointing how Idealabs wasn't able to get a good enough Drupanol yield. Doing so would have brought them more into the lines of "exclusive supplement lab" and less of a "Sigma Aldrich rebadger". Maybe the new product has its own synthesis?

Hair: I’m at the point of only using hot water now. I used to have really oily hair when I used standard shampoo. Transitioning from that, corn starch worked decent as a dry shampoo (I’d still rinse it out at the end) but it was messy and took a while for the corn starch to soak up all the oils. Vinegar rinses left too much lingering smell, sometimes even after following up with baking soda. Baking soda alone seemed to strip my hair and have it extra frizzy. That was likely a result of the alkaline pH, as mammal hair tends to do better with slightly acidic pH. Now, hot water alone seems to have it at an optimal amount of natural sebum. Body wash: I usually only use hot water in the shower too. I made my own bar soap with coconut oil, olive oil, and palm oil. If I need it, I’ll use it, but usually it’s unnecessary. Washing off sweat and bacteria doesn’t seem to be aided by a surfactant; put into other words, soap doesn’t do anything to “clean” your skin if you don’t have outside dirt and oil present. Hot water is enough to keep me smell-free (I have people that would tell me.) Washing the skin with soap also seems to disrupt the body’s Vitamin D production/conversion process. That makes it seem to do more harm than good imo. Hand soap: I made my own liquid soap with the same above ingredients (different hydroxide base used for liquid,) and glycerin. Great for dishes too. I use an emptied out Dial soap bottle with the foaming dispenser head because homemade liquid soap (like Castile soap) can harden in the air and clog the nozzle. Foam head fixes this.

@sphagnum its probably totally fine now I just vowed to not buy stuff from them because their customer service around it sucked so bad, they refused to refund me because my bottle was expired, and that was annoying because logically the bottle being expired does not negate the fact they sold me a bad product, and secondly, I wasnt contacted properly about it, they could have sent me a letter via paper mail if I wasn't checking to see if they emailed me. The way their customer service person talked to me was just shameful from a good business perspective. I just dont have time for companies run by, staffed by people like that. for k2 I just buy it from idealabs, who get it from sigma or some other reputable supplier and just mix it in oil and bottle it. the only reason I do this instead of buying the powder myself and doing it is apparently k2 mk4 powder is sensitive to light and im too lazy to setup a darkroom mixing apparatus or something. im assuming idealabs mixes it in a darkroom if its required but I have no idea as no details like this are ever given. If I found out HN has some sort of amazing pregnenolne now I would cope and buy it, but they are just selling microbially produced pregnenolone, which isn't that big of a deal. I mean it's cool, and great and all, but I haven't seen any proof that microbially produced preg makes a better end product, and secondly it's funny actually because microbially produced citric acid is really le bad according to peaters.

Ok, I have something interesting to report. Yesterday I started with 20 drops in the morning like I've been doing since last Wednesday. However, later in the day I did 5 more due to some exercise earlier and some potential evening stress (A Christmas Carol play). Then I followed up with 5 more drops right before bed. I'm not sure if it was the 6 keto p4 or not, but I slept very soundly. Note that I also don't know what the half life of this stuff is. Anybody here know the half life?

@AL ok thanks. Looks like the purity is 99.5% ?

@disfrutarlo probably depends on which pharmacy you go to and your aura presentation when approaching the pharmacist

@jamezb46 said in GABA powder: The heart and digestive system both have GABA receptors, so even if oral GABA is not CNS-penetrant, who cares? I'd like to try to put the ball back in the center. The question is not to know/ confirm that GABA powder can or not cross the BBB, nor whether there are GABA receptors in the gastrointestinal tract and in the muscles (cardiomyocytes and the cardiac conduction system). Yes, there are some. The main question here is that there is interaction between the microbiome and the vagus nerve. We know butyrate is a substitute for several strains. Butyrate is the star among SCFAs (with propionate) as it upregulates the tight junction proteins (occludin, claudin-1 and -4and ZO-1 (zonulin): Tight junction expression, anti-inflammatory signaling (via HDAC inhibition) and hypoxic barrier maintenance (via oxygen consumption in colonocytes). Butyrate literally energizes the gut barrier. So if we accept that the GABA shunt is a pathway for enhancing a well-balanced microbiota, no need to know / confirm that GABA powder can or cannot cross the BBB. GABA → Succinate = substrate for some bacteria that convert it into butyrate, a key SCFA. But we should know how and when to use GABA powder. More info: How is GABA powder useful for microbiota? GABA → succinate → butyrate pathway: The Microbial Power Route. How gut bacteria convert GABA through the shunt and succinate pathway to fuel and protect colonocytes of the linen walls https://mirzoune-ciboulette.forumactif.org/t2153-english-corner-how-is-gaba-powder-useful-for-microbiota#30480