@TexugoDoMel
Thanks! Thats the one I meant.
The results arent as encouriging as I hoped, but still good.
They had two Intermittent methionine restricion (IMR) groups, both of them were fed 3 days of a methionine restricted diet followed by a low methionine diet for 4 days in case of IMR1 and a no methionine diet in case of IMR2. They had a continuously methionine restricted diet as a control group
In terms of health effects only IMR2 was really capable of keeping up with continous MR. IMR1 had benefits but not quite as much.
Unforuntely its not really possible for people to have a no methionine diet.
Plus, none of the groups ate any cysteine. And only 0.02% in the diet is able to remove the benefits of MR. So Im increasingly worried about cysteine, since in most of the animals studies on MR, it is 0, which is hard to replicate in humans.
<img src="https://onlinelibrary.wiley.com/cms/asset/5bc56635-0d01-43e0-baf4-fa08c37470ab/acel13629-fig-0001-m.png" alt="Details are in the caption following the image"/>
So continous MR does seem to be quite a bit superior to intermitten MR ,which can also be seen by the other data on liver and hormones in the study.
The longer you restrict methionine, the better.
An interesting finding of the study was that alternating high and low methionine days had a similar effect as the 3-4 approach, which underlines the flexibility of this diet.
So if you feel have a good week ,you can have a high protein day once a week and if you have bad week 4 times a week and still get a lot of benefits.<img src="https://onlinelibrary.wiley.com/cms/asset/5bc56635-0d01-43e0-baf4-fa08c37470ab/acel13629-fig-0001-m.png" alt="Details are in the caption following the image"/>