@CrumblingCookie thanks for sharing. Great read.

Da ich wohl jetzt auch Milch vertrage ... Welche ist die beste Milch ?
Ich trinke gerne Berchtesgadener Land.

@tubert thanks for your experience. I will add sodium butyrate first since I already own it. And after that maybe potassium bicarbonate. It's cheap and available so why not .

@Hearthfire I think they are certainly a factor of many.

Anecdotally I can say that I've noticed for years that anti-fungals like boron, MSM, etc. have decreased hair loss .

@Hearthfire very interesting, thanks for sharing.

I didn't find anything on potassium bicarbonate and hair loss directly. But at the very least the bicarbonate should increase local CO2, which is helpful.

But the fungal connection is quite remarkable!
In this study, People with hair loss almost had a 10x higher prevalence of a fungal scalp infection called Malassezia. That correlation is so strong that it seems likely that there's causality as well.

"The prevalence of positive smears was significantly higher among subjects with hair shedding than among normal subjects (89.92% vs 9.52%, p<0.001).
https://pubmed.ncbi.nlm.nih.gov/16901187/

In this study the difference was only 20% .
But they found that Malassezia, is higher on the top scalp in balding people than in the occipital region, which doesn't bald. So again there seems to be a connection between Malassezia and balding. Making potassium bicarbonate an intriguing option .
https://pubmed.ncbi.nlm.nih.gov/31240449/

"The scalp commensal organism, Malassezia, has been recognized to be a source of oxidative damage. "
This might be one of the reasons why anti-oxidants help with hair loss.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6369642/

Sodium butyrate is anti fungal, making it an even better candidate .
https://pubmed.ncbi.nlm.nih.gov/21911344/

@CrumblingCookie yeah good point. That is an aspect of hair loss I've almost never come across.

I'm wondering what I've been doing to my scalp biome by applying 35% alcohol everyday . But from the looks of it, it seems to work. My hair looks better. Even though I was worried that the alcohol might make it dry.

I think I'll use between 0.5-1% of NaB to be sure.

@cs3000 said in Studies showing cancer reversal / shrinking:

In the modern trial ~40% of the people got complete remission of their tumors taken orally daily, without dietary changes mentioned just added vitamin C. Koch injected it just 1 time into muscle, then waited a couple weeks and repeated that twice more if needed

Nice can you link this trial ?
Is the vitamin C there to help it cycle between reduced and oxidized ?

@CrumblingCookie
Great points !

Butyrate could indeed feed the TCA cycle and increase scalp ATP.
It's a small molecule and very water soluble so it should be possible to add it to my formula.

I found an in vitro study that directly corroborates what you said :

• Butyrate delays catagen phase in hair follicles
• Increases autophagy
• "...may be exploited to promote human HF growth, metabolism, pigmentation and/or antimicrobial defences."
  https://www.morressier.com/o/event/62d558b38a1a1f00195adc16/article/62fa00a7cf455b001a73dd1e

Here's another study showing sodium butyrate increases autophagy and inhibits mTOR.
https://pubmed.ncbi.nlm.nih.gov/37686278/

Since these beneficial effects seem to depend on the AMPK-mTOR-autophagy axis that might explain biotin's strong anecdotal evidence for helping hair.
Biotin increases AMPK and thus inhibits mTOR and induces autophagy.

@AinmBeo you can still buy the exact same stuff. It's just labeled as research chemical. Similarly to idealabs.

Somebody else posted a study (I reposted it somewhere too) that Niacinamide did NOT have beneficial effects on hair health.
Based on other studies Im starting to think that they're not interchangable when it comes to all effects. I think they both have benefits though .

I have previously posted studies showing finasteride/dutasteride can cause penile fibrosis, down regulation of the androgen receptor and upregulation of the estrogen receptor.

https://lowtoxinforum.com/threads/dutasteride-finasteride-cause-fibrosis-of-the-penis-and-prostate-decrease-androgen-receptors-increase-estrogen-receptors.39863/