@tubert makes sense! thx

@BroJonas @raytreats yup this guy is great. keeping a stack and doing incline presses and chest dips is the way to get big pecks fs.

@cs3000

According to the first link you posted, forskolin dephosphorylates the androgen receptor, not phosphorylates. There is an increase in the 110 kDa AR isoform and a decrease in the 112 kDa AR isoform. The latter is the phosphorylated isoform.

Specifically, it was with the phosphorylation of serines 641 and 653 that Forskolin interfered.

When the dephosphorylated AR was analyzed in terms of its transcriptional activity, it was observed that the regulation of two genes: PSA and the beta 1-subunit of Na,K-ATPase was inhibited relative to control.

They also claim that the 110kDa AR had only 40% of the maximum ligand binding of the 112kDa phosphorylated AR. I suppose that means that its ligands (androgens) did not bind as effectively to the dephosphorylated AR, thus limiting the amount of gene transcription that androgens could cause relative to interaction with the 112kDa isoform.

Now, that all looks quite troubling, except that the AR has a half life of only a few hours. So, if you take Forskolin, it seems consistent with what we know that the AR that your cells synthesize within a few hours of peak serum levels will be the 110kDa isoform, but that doesn't mean that the next AR that is synthesized will not be the 112kDa isoform.

Increased cAMP also turns on genes associated with ramping up steroid hormone production, so the net outcome is ... who knows

That's why we need people to actually try it and report back. You will never be able to figure out the net effect on paper alone.

memory

DO MIRBEGRON

@alfredoolivas do no harm and due no harm are both correct ... somehow..

I would rather listen to Paul Carter (lifteunbang on IG) than Mentzer advice, if you want to maximise muscle gains. He promotes high intensity, low/ optimal volume, who seems to get it right.
High volume is wrong, but Mentzer was wrong too. The truth is somewhere in the middle.

4-6 hard sets per muscle group, to failure, per workout, twice weekly frequently will maximise muscle gains.
That’s like doing 2 exercises per muscle group, in a workout.

On a chest and shoulders workout, you’re doing 4-6 sets for chest and 4-6 sets for shoulder. A total of 8-12 sets total for a workout. That’s perfectly sustainable.

4 workouts per week is optimal, maybe 5 if you really love training. 3 if you’re doing for general health and maintenance.

@Pooooop

That would be IGF-1, which is anabolic, and not GH. Insulin increases IGF-1 levels and fasting increases GH levels

@Uncover yeah thats gotta be other labs trying to shit on them. i have purchased and personally ingested/injected their products for years and its all legit. just order for yourself and you'll see. the orals like dbol and adrol and superdrol give you indigestion like they should given that they are oral steroids lol. inject the testosterone and you will get big, trust me lmao.

Don’t eat less but better. If you eat less than what you mentioned, you’re going to lose muscles.
There isn’t protein enough: in 3 or 4 takes (with a shake for the 4th).
We should try to optimize the level of carburation (impact / target towards thyroid)
Your breakfast is too weak in protein.
Example
Jordan’s oat 50-60 g (Simply crunchy - Honey baked granola)
With Hazelnut milk 240 ml (or soja milk, if you don’t like hazelnut). No rice nor almond milk. No yoghurt if you want to optimize glycemia (insulin spike). Not now.
Pecan nuts 6 halves (or 8 macadamia nuts if you want to avoid 1.5 g PUFA. But taken apart because hard to bite).
Coconut shredded (very thin sliced) 4 big tbsp.
A protein: Gouda cheese 1 slice (45 g) (vit K2) or ham 50 g.

Note1: when eating PUFA, coconut oil is required (SFA). 1 tsp.
Note2: If you aren’t hungry for the breakfast, change your evening meal.
Note 3: for 220 lb / 110 kg, you need as protein:
At least 1.2g x 110 = 132 g protein (=> 4 x 30-35 g)
Recommended level: 1.8 – 2.2 g x 110 (=> 200 g – 240 g). Not realist without an enzyme supplement and a shake with protein powder.
Note 4: you’ll need a potassium supplement and progressively enough fibbers (30 -40 g)

FYI
https://bioenergetic.forum/topic/3708/impacts-of-protein-quantity-and-distribution-on-body-composition

@the_black_jew, right, not all of them have one. Ys with one can be located via their website:

https://www.ymca.org/find-your-y?distance=175&type=branch&facilities[]=75

About 16 years ago when my spine collapsed and I was relearning how to walk, I joined the Y down the street from me to use their pool as part of my rehabilitation and they had a climbing gym that they had recently built. I’m not sure if they still do this but at the time, the Y gave a discount on membership fees for those who were disabled and low income.

@Luke I get good sleep, hasn't made a drastic impact on my weight though

@cokefiend Yeah I agree, focusing on reaching your energy requirements with lots of carbs is the main thing. For muscle building there isnt really any reason to go over 1-1.2g/kg

@ATP do you use BCAA?

@Cezar4911 The former part of message is good point. When it comes to the latter part I have to say that Thailand is a weird place. There have certainly been some retarded cases. You can buy and blast steroids like crazy but importing is a different thing here. They are suprisingly strict with it. They started interogating me for buying aniprin aspirin. Im sure I must definitely been unlucky regarding that though...

Also freedom is so important to me that I just see people not caring for it like its a baby crazy or unknowledgable haha (altough I have been risktaking regarding this before so I still get how its possible to think that way, but I regret that.). I worked so much without sleep just to escape the 9-5 and I am not willing to lose this fooking freedom after all that. But I am not willing to not take my hormones either slurp 😋

Soon I will be able to buy anything zero risk though hehehe... (Im totally joking cough cough) 😜 ... Or am I du dudu dudu🕺

@grymsky90210 one of the earlier ones I'm not certain

@sneedful said in mysofascial release, foam rolling, lymphatic massage, massaging etc:

I get immense benefits of relaxation and anxiousness relief from rolling on various shape and hardness balls and rollers.

Me too.