@yerrag oleuropein and hydroxytyrosol from olive leaf may be better than black seed have you looked into this

My pleasure, @sunsunsun. And thank you.

@Peater0921 Not Europe, however I've been using the ones I got from Turkey (went into a proper pharmacy and bought them OTC), hope that helps.

@alfredoolivas a random skibidi gust of wind gonna kidnap you one day if yoy go any lower

@ChroncStresChris said: Any ideas? Hi, HD riboflavin is a good choice but drowsiness is a side effect. I cite: High-dose riboflavin (vitamin B2) may improve sleep quality by reducing perceived stress, fighting cellular oxidative stress in the brain, and supporting the nervous system and energy metabolism. [1, 2, 3] Symptom Check: Drowsiness is not a standard toxicity symptom of B2, but clinically reflects a sudden parasympathetic shift or "rebound fatigue" when a chronically exhausted nervous system finally drops its stress drive. [1, 2] What I would manage and how I see the problem: Every other day 200 mg B2. 3 times a week a B50 complex (co-enzymed) (the 3 other days). Not every day. Mg bisglycinate powder 2 x 1.3 g at the beginning. Then 3x when accustomed. You’ll probably need beginning with half the dose when suffering from SIBO (tolerance). Don’t force the speed or your brain will register it as a toxin. L-theanine 200 mg 1 hour before bed. To help relax and improve deep sleep. One week later, we'll see for dysbiosis and energy. Explanation: The Reason: Magnesium acts as a natural brake for the nervous system. It works hand-in-hand with B2 to stabilize the mitochondria and prevent the "emergency brake" feeling that causes daytime fatigue. Smaller, frequent doses maximize intestinal absorption and prevent bowel tolerance issues (diarrhea), while the glycine bound to the magnesium acts as an inhibitory neurotransmitter to calm her fried nervous system. The L-Theanine (200 mg) Knockout: L-theanine increases alpha brain waves and blocks glutamate receptors. This directly dampens the neurological "noise" and hyper-arousal caused by her high estrogen and chronic stress, allowing her to transition into deep sleep Splitting the dose B2 (in 2 takes 100 mg, the same day). The B2 / B-Complex Alternate Balance: High-dose B2 pushes the mitochondrial and liver pathways hard. Giving it every other day prevents her system from getting overwhelmed (+ rate-limited assimilation). The B50 co-enzymed complex on the off-days ensures her body has the necessary cofactors (like active B6, B9, and B12) to actually utilize that energy without hitting a metabolic bottleneck. When the sleep gets better, we’ll manage dysbiosis. You’ll probably have to calm over-reaction from the stomach linen with plant extract from melissa and curcumin (both are here required but only in the liquid form, otherwise curcumin is irritable). We call it: EPS (Extrait de plantes standardisées) (Plant extract liquid). Very soft approach for irritable bowels. They are generally available as an alcohol-free oral solution and can be prescribed as a custom blend tailored to individual needs. PS: You need a plan. If you try one molecule after the other, it won't match. Let me see how you see it / how you perceive the pieces of advice.

@hcwilliams Well, it uncouples from ATP production so yes.

I have tried some Cytomel later in the PM, and it doesn’t seem to disturb my sleep architecture like PM Armour does, So is the T4 the problem? I got my hands on NP thyroid, and this week I will try that and see if I have the same issue. By the way, has anyone noticed that NP Thyroid has actually the same formula as the original Armour?

I think I might have figured it out. Unknown to me he had started taking calcium carbonate supplements and was taking his thyroid in the morning together with it for the past few months. It looks like calcium carbonate can prevent thyroid medication from absorbing properly. This may not be the entire reason but something to keep in mind for those who take both calcium and thyroid.

@bio3nergetic Agreed it is a waste of money

@RambleCycle I don't address people who did't personally ask for. Lost of energy ... => Dysautonomia possible when there is a problem in coordination, a lack of thiamin and mental disturbance. Not the only possibility when there are several linked symptoms.

Berberine Berberine activates thermogenesis in white and brown adipose tissue and increases UCP1; PMID 25423280 Berberine increases testosterone but also prolactin. There might be a sweet spot between 50-100mg/kg (rat dose) where you get minimal prolactin increase with a significant testosterone increase. Maximal T increase was almost 100% https://link.springer.com/article/10.1007/s44345-024-00007-3#Fig2 Berberine sometimes receives criticism because some studies show that it can inhibit mitochondria. Which is true it can:" "...inhibit mitochondrial respiratory complex I” in vitro PMID 18285556 Although in this study it had a positive effect on mitochondria in vivo; it increases mitochondria numbers and prevented mitochondrial dysfunction, which was accomplished via AMPK and SIRT1 activation. "Furthermore, we observe that the prevention of mitochondrial dysfunction by BBR, the increase in mitochondrial biogenesis, as well as BBR-induced AMPK activation, are blocked in cells in which SIRT1 has been knocked-down." PMID: 22027215 "...extended the lifespan ... of naturally aged mice by ~16.49%” PMID 31773901 This study reported an increase in the NAD+/NADH ratio. PMID: 22027215 Berberine made someone on the RPF able to tolerate milk. https://lowtoxinforum.com/threads/does-anyone-here-use-berberine-regularly.41514/post-669774 Increases SERT; lowers serotonin https://pubmed.ncbi.nlm.nih.gov/21647174/

@Mauritio pharma grade is 99.5% +

@zaaku, what helps me during these "bad energy" encounters is making sure I breathe through the nose only and only with the frequency of 12-24 breaths per minute. This is to activate the hippocampus rather than the amygdala, which evokes the fight-or-flight response and which is activated when we breathe fast. Humming (for about 5 seconds at a time) calms me down too.

@16characterstwas I absolutely was. I still remember the exact date this started, because very significant and stressful event happened on that day. It was more than 20 years ago. And every time I experience another big stressful event, my health gets a little worse, never to return to its previous state.

Progesterone can only do good, especially after taking hellacious finasteride, I would be grateful my body can produce any amount and leave it alone. For men, in the short term progesterone's benefits might not be obvious, but in the medium and long term it is spectacular. What to definitely avoid and keep low is estrogen, which progesterone is good at doing.

@sunsunsun gracias

@Mossy said: I would say similar, at least 145 bpm, sometimes considerably higher. When my heart went to that rate, it requires my full attention. It feels like an emergency situation. My point being, it's an acute attack, not something where I can just go on as normal. I would place the cayenne pepper in my mouth and let it sit there until I can feel my rate coming down. Maybe 10 minutes or so. I don't recall exactly. Should it ever happen again, which I hope it never does, I'll time it. I haven't had an episode in a long time. Wow. Just from standing? The most acute episodes I had were in the first 10-15 days. The worst was one morning while I was standing in the bathroom peeing and I was at 130-135. Felt absolutely horrible, like I was dying. I would normally have to do some sprints to get to 130. I continue to improve in all health metrics though. The whole body "ill"/"dying"/"impending doom" feeling has been gone for about a month, resting and active heart rates continue to come down and I make new PRs every other day. The pain in my side/back/muscles has been mostly gone for a bit now, though I did have a little sore/pain feel in my side today, very faintly. So, the cayenne trick is becoming less and less necessary. I will keep it in my back pocket if I have a high BPM attack. For now the only thing I'm continuing is the Zyrtec and Pepcid AC, and I've been hydrating way more than usual, keeping my blood volume up. Those Liquid IV packets are a godsend. One of the best Costco purchases one could make. Great to have on hand for emergency illnesses. Also continuing to improve my diet, been eating healthier, improved my sleep habits. Working hard and doing lots of cardio the past week. Stuff I would not have been able to do a little over a month ago. The thing I'm most thankful for is that the terrible insomnia is gone, I couldn't have taken much more of that. Absolutely horrendous experience that was. Body feeling like I was running from a horror villain all night. I'm back to my normal self of being able to drift into sleep within minutes.

@sunsunsun said: do u have link for 2g out of 10g absorption of glycine I suppose you wanted the justification. Why so little... Full answer here: How much glycine absorbed with powder https://bioenergetic.forum/topic/9482/how-much-glycine-absorbed-with-powder In short: The transporters are quickly saturated with 2 tsp glycine powder.