Useful links
*) Coenzyme et Cofacteur ne se lient pas par insuffisance de Thiamine (B1) (Coenzyme and cofactor do not bind due to thiamine (B1) deficiency)
https://mirzoune-ciboulette.forumactif.org/t2015-vaut-le-detour-it-s-worth-the-detour#29416
*) B1 deficiency and Potassium Waste
Thiamine Deficiency Causes Intracellular Potassium Wasting 04/23
By Elliot OVERTON, DIPCNM CFMP, author at “Hormones Matters” is a nutritional therapist and functional medicine practitioner based in the UK.
https://www.hormonesmatter.com/thiamine-deficiency-causes-intracellular-potassium-wasting/
Thiamine deficiency causes intracellular potassium wasting.
Excerpt:
In short, the bioenergetic state of the cell governs its ability to retain potassium ions and structure water into a gel-like phase. A cell with plentiful ATP can maintain this ability, independent of the “sodium potassium pump”. On the other hand, cells lacking energy lose their capacity to retain potassium, intracellular water becomes “unstructured” and intracellular concentration of sodium ions increases and the electronic state of the cell is changed. This causes water to “leak” out of the cells into the extracellular space to produce a localized edema of sorts. Thiamine, playing a central role in energy metabolism, is partially responsible for maintaining healthy redox balance and a continuous supply of ATP. Hence, it is no wonder why a deficiency of this essential nutrient produces such drastic changes in the cellular electrolyte balance.
*) Thyroïde B1 B2 B3 – Interaction entre les vitamines du groupe B et la thyroïde
https://mirzoune-ciboulette.forumactif.org/t2018-comment-booster-votre-energie#29549
Thyroid hormone (thyroxine) regulates the enzymatic conversion of riboflavin into its active coenzyme forms.
B2 is necessary for the regulation of thyroid enzymes: B2 helps to organify iodine (i.e. the incorporation of iodine for the production of thyroid hormones).
*) Choline is a well-known methyl donor, but it cannot play a methyl-donor role until it is converted to betaine in the liver and kidneys. Avoid chronic high niacin exposure since it might induce a methyl pool depletion.
Excessive nicotinic acid increases methyl consumption and hydrogen peroxide generation in rats
https://www.tandfonline.com/doi/full/10.3109/13880209.2012.697175
https://www.nature.com/articles/hr2011133
*) Anti-Stress & Neuro-Protective Effects of Thiamine (B1)
Mitochondrial Energy Uploaded thanks to Optimized Enzyme Communication
https://mirzoune-ciboulette.forumactif.org/t2045-english-corner-anti-stress-neuro-protective-effects-of-thiamine-b1#29712
Neuroprotective Effects of Thiamine
Impact on mitochondrial respiration – Link with ATP production
Power plant (power station generating electricity)
The role of thiamin deficiency in lower brain dysfunction (dysautonomia)
Nutrient deficiency & interaction of vitamins B
Understanding nutritional & functional deficiencies (enzymatic metabolic block)
How much and which kind of thiamine? (video Elliot Overton)
How to proceed to avoid / limit a paradoxical reaction.