@lunaticred Wait, I did not read the title carefully. I only thought you plan on transitioning to 24h shifts, I did not read about the 4h sleep schedule. Is this even possible? Can you not make it work some other way? You mentioned 12h rest, why not sleep for 8 hours and use the rest for eating/traversing? What makes you sleep only for 4 hours if the rest is 12h long?

https://www.youtube.com/watch?v=2kwCc5uqJv4 https://www.youtube.com/shorts/WVk9s6bRQ0c

@wester130 my performance is way better so Idk how lowered metabolism jives with that.

@hawk1 Thx bro cheking rn

this waking in middle of night thing completely stops for me when I eat lots of vegetables im almost certain it's from mild acidosis. maybe low glycogen is a side effect or something of this. on days I eat abundant vegetables I completely sleep through the night.

@wester130 you’re not getting it. USP means something. You apparently don’t care about standards and honesty. Writing Andriol on there is like me writing Ferrari on a Ford.

@LunaticRed Peat liked uric acid more than most people do. In his caffeine article he wrote "Uric acid, synthesized in the body, is both a stimulant and a very important antioxidant," and said part of how it works is "by modifying the activity of the enzyme xanthine oxidase, which in stress can become a dangerous source of free radicals. Caffeine also restrains this enzyme." So my guess is the muscle protection comes from calming xanthine oxidase during heavy exercise, and dropping uric acid is the part I'd be wary of long term. Did any of the papers compare it with caffeine or theophylline?

@user1 Hello user1, hawk1 here. I was joking. Seems like your friend could use some help though

@alfredoolivas i rememeber reading it is needed for clearing oxidated dopam from synapses

Useful link on B6 vitamin in relation with neurotransmitters (In French, translator required). a) https://mirzoune-ciboulette.forumactif.org/t2032-effets-de-la-vitamine-b6-sur-les-neurotransmetteurs b) Moderate sensory neuropathy caused by vitamin B6 Reducing brain inflammation with vitamin B6 https://mirzoune-ciboulette.forumactif.org/t2038-neuropathie-sensitive-moderee-par-la-vit-b6 Excerpt: “For individuals suffering from brain inflammation—whether mediated by disease, medications, or adverse vaccine reactions—vitamin B6 could potentially dampen inflammatory cascades and improve quality of life.” Chandler MARRS, PhD

@Mauritio Did you ever get to the point where you can tolerate preg/prog? If so, what do you think moved the needle the most?

You’re welcome, @SilvertipConch. I like dates, too, especially covered in white chocolate and sprinkled with some coarse salt. If you like chocolate, it’s super easy to make and another good use for the powdered milk: https://www.alphafoodie.com/how-to-make-white-chocolate/

@thebiooracle said: He wrote that it tends to locally activate thyroid secretion "by a variety of mechanisms, increasing cyclic AMP and decreasing serotonin in thyroid cells, for example, and also by lowering the systemic stress mediators." Interesting, thyroid mostly expresses PDE8, same form mostly present in leydig cells, inhibition of which significantly raises testicular steroidogenesis.

Have to add that after acid-base balance is restored, magnesium intake can be used to regain and sustain OXPHOS.

There's something fishy about Hans. He claims he's been doing all these self-experiments where he takes a mega dose of something for 2 weeks and does before and after blood tests, and frequently other tests like stool tests. If it were all true, he'd be practically living at a clinic! He says doctors are useless and that he pays for all his own private tests. But then makes a post about having a chat with his doctor, and discussing various results with him. He never posts his labs, as others have pointed out. He could just be making it all up, for all we know. What he does do, constantly, is try to make money off his claims. So I'm a bit dubious.

@jimmynelson said: When I was on cyproheptadine (very low doses) for a couple months I ate like a monster but I did have resolution of some long standing issues which I think were being held up in "healing" by stress hormones. What was this "very low dose?" When I first experimented with cypro, I tried doing 1mg per day. I only lasted a couple of weeks, as I had this zombie like tiredness that would persist for most of the morning. Might just have been very tired in general all day, can't really remember. I stopped, and things got back to normal. Later, I decided I would use some higher doses (starting at 4mg, going up to 8mg) and thought I would just push through the tiredness, however long it was. To my surprise, it was much milder this time, and only lasted about 3 days or so. After a while, some doses of cypro actually gave energy. I think there is something to an initial "loading dose." Others on the old RPF mentioned the same sort of thing, that 4-8 mg as a starting dose caused minimal tiredness, but 1 mg caused much more tiredness. I think some suggested cutting back to 1mg after a week or two of loading, but I just kept it at 4-8mg, and saw good results. I think one RPF member even said Dr. Peat recommended a loading dose protocol similar to this, but I never saw or heard any direct quote from Peat in this regard. Another potential option is selegiline. It's an MAO-B inhibitor, so it prevents the breakdown of dopamine, as opposed to being a Dopamine Agonist.

@wester130 I just do the medium high seat biking due to convinience. Should be higher tbh.

why are you so weird