Here's a very peaty explanation of CO2 by a german doctor in bamberg. Might be worth a shot for some. https://dr-kersten.com/kann-die-co2-inhalation-den-energiestoffwechsel-normalisieren

https://youtu.be/0vzrJkJ-gQE

@GRay said in mk4 dosing?: isn't only the k1 that effect clotting? K1 and K2MK7 too affect clotting. For Chris Masterjohn, MK7 would even be better. Chris Masterjohn : « The ultimate vitamin K2 resource »). https://chrismasterjohnphd.com/blog/2016/12/09/the-ultimate-vitamin-k2-resource/ Excerpt 1: There is reason to think MK-7 would be better at supporting blood clotting. “MK-7 is not just three times better than K1 at reaching bone; it’s also five times better at supporting blood clotting (Schurgers, 2007). This may be because the greater fat-solubility of MK-7 makes it hold on more tightly to the membranes within liver cells, making it stay active in the liver much longer rather than being released and broken down (Shearer, 2008). The liver is where clotting proteins are made, so more extended activity in the liver would explain why MK-7 could better support blood clotting. If this is correct, other long-chain MKs such as MK-8 and MK-9 probably share this property as well.” Additional comment: The risk of improper clot formation is increased in cases of low vitamin K levels. Vitamin K (VK) does not cause or dissolve blood clots. However, VK enhances the function of both these systems. VK1 can therefore be seen as a facilitator: Procoagulant factors are VK-dependent. Remind that platelet formation requires 10-12 days after taking aspirin, whatever the dose is (baby or adult caps).

@gg12 increased adrenaline compensates for lower thyroid function. Increased adrenaline always made me want to make a million plans

@peaty-runescape I had a period coming back after being in menopause for over a year. I am also careful. I feel moody too when I take it.

@LunaticRed I shave my arms and apply it there and the inside of thighs currently.

@bio3nergetic this is reasonable, but hear ye, hear ye, some dudes are deeply, keanly, eagerly, needy, of healing an exceedingly teeny weeny thingy, albeit a bigly hearted beefy meany Peeny, by any means necessary. speaking for a friend.

@TexugoDoMel I haven't used it for a week now because I didn't like my moles darkening. So, I still have 19 more vials left sitting around and I have no clue what to do with them. Looks like maybe PT141 would still have the pro metabolic effects without the darkening but the MCR affinities are a little different. Maybe if I want a tan I could experiment with gene therapy to change the natural skin color? I don't know what Ray Peat thought about gene modification though.

my eyesight goes from -4.0 glasses to perfect 20/20 can see eagles in the distance and individual branches of trees a mile away and license plate numbers and letters when the sun is out and I have good posture

@thezynmaster have experience with tbol from PPL, Tbol is like a milder form of dbol or anadrol. You need testosterone or else you will crash hormones after a few weeks / post cycle. Just run 250mg total test pinned twice a week with tbol and you will get strong as fuck if you lift right. Ive been buying from PPL since 2017 theyre good to go. Not a shill just a dude whos been doing steroids for a long time lol. For the past 6ish months ive been taking tiny doses of anadrol (from PPL) as well, Ive put on 85-100 lbs in all my lifts but also been very consistent and on 250-300mg cypionate a week. You will for sure have a boost in strength and endurance when lifting but the drugs are only as important as how you workout, what you eat, and how well you sleep. for reference from personal experience with the orals in terms of strength/side effects. Superdrol>Anadrol/Dbol>Tbol I have taken all and Tbol is was milder than Sdrol and the anadrol/dbol. I also was taking milk thistle or TUDCA daily to help with liver strain.

@gg12 image is fake proves chem trails and powershortages simultaniously?

@engineer interesting I'd like to see that study. Georgi cured cancer by giving mice high doses of biotin (HED ~200mg), other b vitamins and aspirin. And there's also a few long term studies on very high dose biotin for MS and i don't recall that they saw any increased level of severe side effects (like cancer).

@cs3000 I interesting ! Oleanolic acid sounds interesting, too. I took ursolic acid today for the first time. And it caused some hair loss but also a profound sense of relaxation that haven't felt in a while.

Yes confirmed, I asked some years ago, that is what they use.

"Phytates are not a health concern for those who eat a varied and balanced diet. However, for those on a poor, monotonous diet, high levels of phytates increase the risk of mineral deficiencies, which is why various techniques are used to reduce phytate levels in food." I guess the question is, why would someone take to a variation of a "a poor, monotonous diet". And could that include some interpretations of advisories found around bioenergetics.

@LucH Why is your AI so fucking chill?

@jamezb46 I remember 18 nor T, but were we talking about a different steroid? Wasn't 3beta-hydroxy-pregna-1(10),4,9(11)-trien-2-one mentioned by Patrick Arnold in a phone call to Ray Peat?

@sunsunsun bruhnem like 10 min boil milk then add oats lower geat stire for like 5 min

This picture of VDR knockout mice being "lean" and "obesity resistant" is taking some of the trees for the forest and claiming it's the whole forest. If you are insulin resistant, generally force-feeding a lot of carbohydrate substrate without any other measures is probably not a good idea. Are carbohydrates bad? No. Vitamin D has been skewed, I am sure intentionally, as a general calcified public is also "paradoxically" calcium deficient, or more aptly on a very low calcium:phosphate ratio, focusing on inflammatory, active D (1,25) paints the perfect, evil picture of vitamin D overall and is frankly wrong. Hydroxylases tightly regulate local conversions to 1,25 from 25. What interrupts this regulation? Calcium deficiency, estrogens, PUFA. In other words pre-inflammatory state. Knockout mice, barring all other factors of health - which is usually the game here in these worthless studies - will not experience this inflammatory, dysregulated system. And looking only at this narrowly through a lens, you derive your conclusion you are looking for: manipulating the meaning and function of things. In reality, in the real world, the better method in avoiding these inflammatory responses is, you guessed it, sufficient calcium, low PUFA, in turn keeping estrogen in check, and being careful of other inflammatory things. Much like the knockout mice scenario, removing some apparatus to prove something is bad, when that something itself is hijacked and fed into a detrimental cycle is a sleight of hand, not proof. Vitamin D is not the problem, and VDR knockout doesn't prove it is, only in that if 25 is converted via inflammation. Lipopolysaccharide derived MKP-1, inhibition by inactive D already shows vitamin D is an anti-inflammatory, but not 1,25. And 1,25 is one of the resident experts of inflammation, when conditions of health are not met. Get tho9se conditions met and D does what it does that is good for us. By the way, progesterone and methylene blue also help Also, "constant milk intake" is an absurd, hyperbolic suggestion. I am certain nobody here has an IV of milk coursing through their veins 24-7. You have some milk throughout the day, then we all fast whether we know or not: it's called sleep.