@Hearthfire said in Tracking down the mysterious cause of Dr. Paul Saladino's shockingly rapid aging:

Low Vitamin D and using sunscreen is what causes cancer and aged skin look.

Do you have any sources/studies/testimonials about it ?

@yerrag
I think it is not digested as completely as cooked meat unless one has strong stomach acid. If I'm not mistaken Aajonus recommended to accompany raw meat with raw honey to supply digestive enzymes. Well, raw meat provides with more glutathione but there are other sources of it.
I would consider it as occasional pre/pro-biotic food. It might cause flu symptoms when cold and not recommended when defrozen.

Ray got drooping/sagging skin by age 47 . He patched himself with pregnelone.
Also look at his neck on the left picture. He looks too old for his age.
Just wondering if he was under a lot of stress in that time.

In 1983, the ocean current called El Nino caused
Oregon's weather to stay cloudy and rainy through the
summer. I didn't have my usual summer recovery from
"winter sickness," and by November I was becoming very
sick. During a two week trip I felt perfectly well, but except
for that short time I kept getting sicker and sicker (with
inflammation of arteries, dental abscesses, asthma, migraines,
and colitis). Lying in bed one day trying to understand what
had happened during that two-week trip, I remembered that I
had used the vitamin E containing a residue of pregnenolone
on the trip, but used pure vitamin E after I got home. I
immediately got out of bed and took a pinch of pregnenolone.
In about an hour, all of my symptoms had stopped, and for
over a week I was healthy and energetic. But then I got sick
again, and was so distracted by the pain that it was several
days before I remembered the pregnenolone. Another pinch
had the same dramatic sudden effect. Since then I have taken
some almost every day. While I was sick I had pictures made
for a passport, but they looked so odd that I got several more.
The best of those, the least haggard looking, is reproduced
here.
NOTE:
After using pregnenolone for several years, I noticed
that the slack skin and other signs of aging were coming back.

I think raw meat is poorly digested but may be beneficial as prebiotic ( foster growth or activity of beneficial microorganisms ). Being poorly digested means less iron is absorbed , and also mimicking fasting /low calorie.

@Insomniac
Yeah, Haidut rocks.
I think the sun in DC is not as strong as in San Diego.
I would like to see haidut surfing in the Pacific so we can compare their physical fitness.

if we do lots of exercise injures are unavoidable , but we do it for fun anyway. Another option is to stay at home and drink coffee

Ray Peat's Newsletters

"Some of the obvious changes of aging, such as loss of muscle (Martinez-Moreno, et al., 2007) and gain of fat (Bahadoran, et al., 2015) and decreased sensitivity to insulin (Ropelle, et al., 2013), are produced by increased nitric oxide."

"In people with Parkinson’s disease, increased amounts of iron, nitric oxide, and prostaglandins have been observed."

"a diabetes-like state is created by nitric oxide damage, forcing the use of fatty acids instead of glucose for fuel."

@SpaceManJim said in Bryan Johnson cooling himself for longevity? Waking temp of 93.4. Seems like a bad idea:

@Gardner how is lowering his metabolic rate going to help with longevity? What happens when he gets sick or injured?

He would be already sick and injured because he's been pursuing this quite a while. He probably knows more than what we think of him. He definitely won't share all his secrets. There will be more peope like him and they don't want everyone to live to 300 yo. He may even fake his death at some point so everybody says...see , even Bryan couldn't make it.

Low metabolic creatures live long ...whales (2 to 37 heart beats per minute (bpm)), crocodiles (24–40 bpm) , turtles (25 bpm) . They are very resistant to cancer and at the same time high persentage of highly unsaturated fatty acids (HUFA) in tissue .

His goal is different , he is aiming at longevity . I guess he wants to bring himself to a reptile like temperature/metabolism so he can live to 200 or 300 yo and then even longer and passively (low stress) observe how humanity develops. He can afford low stress life.

Trump doesn't wear glasses, no presbyopia for him , pretty impressive .