@Norwegian-Mugabe It is a historical coincidence that Franz Kafka consumed large quantities of unpasteurized milk as part of his strict vegetarian diet, [image: 1767126158963-06b3c447-193a-4966-a8df-01ce6b3c4a46-image.png] which he adopted for general health purposes and to ease ailments like migraines and insomnia, long before his tuberculosis diagnosis. He consumed unpasteurized milk and believed it was a healthy choice, a common view before the understanding of bacterial transmission was widespread. Milk doesn't necessary causes hairloss but there migh be a connection between his tuberculosis and habit of drinking unpasteurized milk

@alfredoolivas I actually just came by to kiss your forehead goodnight... but since you were out so cold, I figured I'd provide some manual fuego-genesis for you as well. Turns out your metabolism is much more cooperative when you aren't talking

New product is ready, will announce on a separate thread soon.

@sunsunsun true lol

@Korven said in Colostrum suppresses serotonergic signalling in (overtraining) rats: wonder if just popping a cyproheptadine can do this well

@jamezb46 xD

Comment “Results show that epigallocatechin gallate (EGCG), the main polyphenol in green tea, can neutralize the carbonyl-amino cross-linking reaction and inhibit LF formation, but the underlying mechanism is unknown." LF = lipofuscin. Article https://bioenergetic.forum/topic/9017/neuro-degeneration-a-multi-factorial-approach => I’d like to develop this approach. Not only from one side: multi-factorial. When talking about neuro-degeneration we should take the whole context into consideration to avoid plaque. After having read an article on the lack of B12 when bringing the RDA for aged people (> 40 yrs.) (1), I decided to write an article to show / to tell how I manage to optimize. Afterwards I submitted my plan to AI and ask it for comments. =>The prevention of neurodegenerative and vascular disorders rests on two pillars: metabolic flexibility and membrane integrity. See my "Metabolic Safety" Protocol if you want to go deeper.

Useful links *) Coenzyme et Cofacteur ne se lient pas par insuffisance de Thiamine (B1) (Coenzyme and cofactor do not bind due to thiamine (B1) deficiency) https://mirzoune-ciboulette.forumactif.org/t2015-vaut-le-detour-it-s-worth-the-detour#29416 *) B1 deficiency and Potassium Waste Thiamine Deficiency Causes Intracellular Potassium Wasting 04/23 By Elliot OVERTON, DIPCNM CFMP, author at “Hormones Matters” is a nutritional therapist and functional medicine practitioner based in the UK. https://www.hormonesmatter.com/thiamine-deficiency-causes-intracellular-potassium-wasting/ Thiamine deficiency causes intracellular potassium wasting. Excerpt: In short, the bioenergetic state of the cell governs its ability to retain potassium ions and structure water into a gel-like phase. A cell with plentiful ATP can maintain this ability, independent of the “sodium potassium pump”. On the other hand, cells lacking energy lose their capacity to retain potassium, intracellular water becomes “unstructured” and intracellular concentration of sodium ions increases and the electronic state of the cell is changed. This causes water to “leak” out of the cells into the extracellular space to produce a localized edema of sorts. Thiamine, playing a central role in energy metabolism, is partially responsible for maintaining healthy redox balance and a continuous supply of ATP. Hence, it is no wonder why a deficiency of this essential nutrient produces such drastic changes in the cellular electrolyte balance. *) Thyroïde B1 B2 B3 – Interaction entre les vitamines du groupe B et la thyroïde https://mirzoune-ciboulette.forumactif.org/t2018-comment-booster-votre-energie#29549 Thyroid hormone (thyroxine) regulates the enzymatic conversion of riboflavin into its active coenzyme forms. B2 is necessary for the regulation of thyroid enzymes: B2 helps to organify iodine (i.e. the incorporation of iodine for the production of thyroid hormones). *) Choline is a well-known methyl donor, but it cannot play a methyl-donor role until it is converted to betaine in the liver and kidneys. Avoid chronic high niacin exposure since it might induce a methyl pool depletion. Excessive nicotinic acid increases methyl consumption and hydrogen peroxide generation in rats https://www.tandfonline.com/doi/full/10.3109/13880209.2012.697175 https://www.nature.com/articles/hr2011133 *) Anti-Stress & Neuro-Protective Effects of Thiamine (B1) Mitochondrial Energy Uploaded thanks to Optimized Enzyme Communication https://mirzoune-ciboulette.forumactif.org/t2045-english-corner-anti-stress-neuro-protective-effects-of-thiamine-b1#29712 Neuroprotective Effects of Thiamine Impact on mitochondrial respiration – Link with ATP production Power plant (power station generating electricity) The role of thiamin deficiency in lower brain dysfunction (dysautonomia) Nutrient deficiency & interaction of vitamins B Understanding nutritional & functional deficiencies (enzymatic metabolic block) How much and which kind of thiamine? (video Elliot Overton) How to proceed to avoid / limit a paradoxical reaction.

"GENERATIVE ENERGY: Restoring The Wholeness Of Life" is also now available. Amazon: https://a.co/d/jca7Tqh

@Mauritio [image: 1766957715962-screenshot-2025-12-28-at-1.33.53-pm.png]

@LucH - Excellent idea.

@jamezb46 the idea was that even though bakuchiol itself doesn't aromatize to estrogen, its estrogenic effects would essentially take the place of existing estrogen aromatized from different sources. The purpose of the AI would be to reduce aromatized estrogen elsewhere so that the bakuchiol in addition to existing hormones doesn't cause hyperestrogenic symptoms. Of course, this wouldn't be viable if bakuchiol is so estrogenic that an effective dose would exhibit an estrogenic effect greater than what would already be present. I also thought that DHEA became estrogenic at higher doses if there is already of lot of it present. Is that not true? Also, it's disappointing how Idealabs wasn't able to get a good enough Drupanol yield. Doing so would have brought them more into the lines of "exclusive supplement lab" and less of a "Sigma Aldrich rebadger". Maybe the new product has its own synthesis?

@what-about-bob Thanks. I like the summary. How everything all fits in from theae great minds and put together by Ray Peat into more practical lifestyle applicable ideas. I am appreciating how I see myself on the "applied technology" end of their contributions as I incorporate these ideas into my attempt to be my own doctor as I attempt to improve my health. I have been unable for the past 24 years to lower my blood pressure without using prescription medication. But I am seeing the light at the end of this tunnel. It is a long process of learning and I don't give up. Thanks to recent developments in science and technology, I may be able to lower my blood pressure finally using ideas from Peat and his predecessors. What has been helpful is my use of AI as an efficient research assistant and aggregator of concepts and minute details that my own limited human mind can't recall easily and utilize readily.

@sphagnum its probably totally fine now I just vowed to not buy stuff from them because their customer service around it sucked so bad, they refused to refund me because my bottle was expired, and that was annoying because logically the bottle being expired does not negate the fact they sold me a bad product, and secondly, I wasnt contacted properly about it, they could have sent me a letter via paper mail if I wasn't checking to see if they emailed me. The way their customer service person talked to me was just shameful from a good business perspective. I just dont have time for companies run by, staffed by people like that. for k2 I just buy it from idealabs, who get it from sigma or some other reputable supplier and just mix it in oil and bottle it. the only reason I do this instead of buying the powder myself and doing it is apparently k2 mk4 powder is sensitive to light and im too lazy to setup a darkroom mixing apparatus or something. im assuming idealabs mixes it in a darkroom if its required but I have no idea as no details like this are ever given. If I found out HN has some sort of amazing pregnenolne now I would cope and buy it, but they are just selling microbially produced pregnenolone, which isn't that big of a deal. I mean it's cool, and great and all, but I haven't seen any proof that microbially produced preg makes a better end product, and secondly it's funny actually because microbially produced citric acid is really le bad according to peaters.