Dandruff or scalp irritation? Try BLOO.

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    alfredoolivasA
    @engineer @hwisdom <200mcg is the average intake of vitamin K2, that's why they are dosed so low. MK7 is a precursor to MK4, and produces much more stable levels compared to an equivelent dose of MK4. Though the other MKs including 4 are much more active than MK 7. Though MK7 does have some binding affinity to the PXR receptor ("vitamin K receptor"), MK4 has much higher binding affinity
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    hwisdomH
    @risingfire the convertion of p5 into p4 is fast and into DHP is even faster, DHP can and will convert into androsterone which is because of the massive amounts of 5AR expressed on scrotal skin, if you look at scrotal vs like normal skin application of testosterone its very evident that the DHT/T ratio is much higher when its applied to the scrotum, I could never look at some opportunity like this and expect it to be just "fools gold" especially when there are multiple cell culture studies show that p5 does actually indeed convert into potent pheromones as well as testosterone
  • I want to bully danny roddy

    Moved The Junkyard
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    lykosL
    @ThinPicking redeemed lykos
  • I have trouble sleeping

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    @lykos I think the need for more B vitamins is the increase in metabolism. You will increase your appetite on it. That being said I'm not sure it depletes B6 per se but you would need to experiment and look into it. Good luck
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    R
    @dapose around 40 mgs of K2
  • Feeling worse in warm weather?

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    JenniferJ
    @scamp said in Feeling worse in warm weather?: I know warm weather is supposed to provide relief from hypothyroid symptoms Not necessarily. The extra daylight that accompanies warm weather can but with hypothyroidism, the body has a hard time regulating its temperature so both cold and heat, especially heat that accompanies high humidity, can exacerbate symptoms. Prior to supplementing thyroid, I was just as intolerant to heat as the cold and had often overheated to the point of passing out, and Ray talked about how his thyroid shut down when he was in Florida, due to the heat and humidity.
  • Humorous musings

    The Junkyard
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    DavidPSD
    [image: 1769000535042-3b4c71f9-a86f-421c-8b12-3412b701fd8f-image.png]
  • HDL and Cognition in Neurodegenerative Disorders

    Literature Review
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    DavidPSD
    Niacin is the the most potent substance to raise HDL (up to 35%). Apolipoprotein E-containing High Density Lipoprotein Promotes Neurite Outgrowth and Is a Ligand for the Low Density Lipoprotein Receptor-related Protein (1996) [image: 1768937767460-4330412e-970e-4013-bc99-d131cbab7111-image.png]
  • 500% testosterone increase with this one simple trick

    Experimental Logs
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    engineerE
    @PissBoy while you get your lisuride, also get some pansterone and kuinone because they are incredible products too hope you see great results!
  • Any experiences with DHT supplementation?

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    engineerE
    @CrumblingCookie if he's getting those effects from only 10mg then that is weird. Many people take upwards of 100mg and are just fine
  • Source for bulk 6-keto-p4

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    engineerE
    @lobotomize level 10?? [image: 1768926770643-41942f25-9576-4be5-9677-0b6356bce2ee-image.png]
  • Gains from Lapodin?

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    engineerE
    @lobotomize for dht? please share the studies because the consensus seems to be that dht is not anabolic, but I would love to see otherwise
  • Random, interesting studies

    Literature Review
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    A Comparison of Sodium Citrate and Sodium Bicarbonate Ingestion: Blood Alkalosis and Gastrointestinal Symptoms, 2022 500mg/KG BW sodium citrate (SC) is about equally effective as 300mg/KG BW sodium bicarbonate (SB) in raising blood pH and blood HCO3- in healthy people. The increase in the SC group however took about 1h longer to set in and also lasted for longer than the SB: [image: 1768923896919-full-ijsnem.2022-0083figuref1.jpg] I'd say give the citrates a try for simplicity although in this study, the gastrointestinal side effects/complaints were comparable between SC (~35g!) and uncoated SB (~21g!). Whilst the SC also does meddle with stomach pH, it won't react to CO2 (burping, flatulence). The release of HCO3- from citrate happens indirectly through liver tricyclic-acid metabolism. And of course use potassium citrate or a citrates blend instead of the sodium salt. @mossy @ena There are several online suppliers of potassium citrate capsules (~1110mg per capsule, whereof 400mg K) as an affordable alternative to buying the pure powder and dissolving a teaspoon in water two times a day. 10grs of potassium citrate contain about 3.6grs K, 10grs of potassium bicarbonate ~3.9grs K. Although the same amount (by weight) of citrate is not as effective as bicarbonate, on a regular daily basis I think one can shift between using either.
  • 0 Votes
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    TexugoDoMelT
    @engineer SSRIs have a much more generalized effect than a direct 5-HT1a receptor agonist since serotonin will be divided among all other receptors From another study 8-OH-DPAT influences extracellular levels of serotonin and dopamine in the medial preoptic area of male rats [image: 1768918294031-3d46999d-9aad-44ea-8bf1-36bfb5e7c66b-image.png] Pharmacological characterization of 8-OH-DPAT-induced inhibition of rat hippocampal 5-HT release in vivo as measured by microdialysis [image: 1768920594623-d36fbbc0-87ea-42bd-be31-d2f3fde2633a-image.png]
  • Help lowering SHBG

    Case Studies
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    engineerE
    @samsuska Years ago I also tried Tongkat Ali which has eurycomanone in it, which also lowers SHBG, but I didn't like how plant supplements are not standardized so you don't know how much eurycomanone you're getting.
  • The rationale for topical Losartan for hair loss.

    Experimental Logs
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    W
    @Gaston In experimental studies for oral liquid compositions, the following components were mentioned: Active Agent: Losartan potassium. Solvents/Vehicles: Water, propylene glycol, and glycerin. Buffers/Stabilizers: Sodium phosphate buffer, sodium chloride, xylitol, and sweeteners. [image: 1768827007062-7a93e946-cf11-4faa-9f1f-11824f7d869f-image.png]
  • Reversal of hair loss in Mice with “sugar gel”

    Moved Literature Review
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    MossyM
    @Hearthfire Appreciate the detail. Great news on the vellus hair growth.
  • Help with EU Sources

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    MauritioM
    @milkgains_bro ok thx. I've ordered the t3 . Well see ...
  • I will teach you to grow taller

    Moved The Junkyard
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    alfredoolivasA
    @Sugar said in I will teach you to grow taller: Frankfurt plane Is it fun to be this crazy?? I kind of wish I would be like this when my mental health is down the drain.
  • intresting chems source bounty

    Bioenergetics Discussion
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    U
    @lobotomize in bounty coconut+chocolate bars?