@Mossy said in Bile can serve as a reservoir for funghi, making them harder to treat: Do you think consuming beef liver would be enough to help with this? In prevention, yes. Not when contaminated. Copper (Cu): in beef liver (3 oz.): 12 400 mcg in chicken pan-fried (3 oz.): 455 mcg in seeds the best options include sesame seeds, almonds, sunflower seeds, and cashews. A 1-ounce serving of these crunchy seeds can supply around 0.5 to 0.9 milligrams of copper. In pumpkin seeds 1,34 mg per 100 g. 1 tbsp is 7.44 g and brings 99 mcg Cu. => I put 1 big tsp in my smoothie with pomegranate. Ceruloplasmin is a protein your liver makes. It helps copper circulate throughout your body and plays an important role in making the iron that you get from food ready to move from your intestines to organs like your spleen. You need copper to help maintain energy and bone health. So, no direct need for blood or liver needs but well for SOD enzyme. Copper is required for sod enzyme in infection control. Cu and Zn are required for superoxide dismutase enzymes. Interaction between HD take (+/ 1/10 Cu/Zn). And Yes, retinol is also required in the immune process (interaction with A D K). I take 2x/wk. 5 000 UI (retinyl palmitate).

@Cicero see if people got blood tests. That’s the only way you can find out if it’s real or not, no tests for DHT e or p are available to public. I don’t trust them based off of personal biases, when something is rare as a DHT ester in this steroid market, I stay away.

@wester130 Interesting about the strength of the oils, as far as vasodilation goes. I find oregano to be dangerously strong, so that is no surprise it's on the list. I have two versions of oregano oil, full strength and diluted to 25%. I accidentally put the full strength on my skin once, and that was interesting, to say the least. Due to that, I put a white sticker on the cap, with a large red circle, and I added red stripes down the front of the bottle. Same company, same size bottle, with the only distinction being the 25% dilution in small print, until I added these.

@Jennifer Thank you, but please don't worry about being late or not replying.  I think this forum should be a no-stress, take it as it comes, endeavor.  It's one of the freedoms — and I don't know yet if it's a positive or negative — of the modern life, among the many inherent burdens, the ability to dive in and out of topics and conversations, on a whim.  As soon as it becomes an obligation, it kind of takes the fun and benefit away.  And with this information age, we can easily take on obligations far beyond our capacity to handle all of them.  The local town or city has now become the world, to some degree! Ok, that is good to know about yogurt and pancakes. I have actually been thinking of making pancakes.  In my flour research, I see that I would purposely want a lower protein flour.  I was kind of hoping to be able to use bread flour for everything .  Maybe I still can, but it seems normally you wouldn't want to. I appreciate the kind words.  I have slowly made strides in my over all health, as compared to when I first started Peating.  Your success story with thyroid is intriguing, and has me not totally throwing the idea out, though it is down on the list.  It will be interesting to know if your thyroid maintains after you stop supplementing with it...if. Indeed.  I think that is where my natural inclinations to be wary of water prove themselves...when a giant wave pummels me!  I don't know if you've ever been caught under a wave and it pins you to the ocean floor momentarily, but not fun!  Those who are meant for water don't think too much of it.  I'm not one of them, for better or worse. For sure.  Peakcock = rockstar, from any measurement.  (Just don't tell the other male birds that.) One dad is enough...haha.  And the way I approach things, with attention to detail, is to a fault.  It's the error of perfectionism, which ironically, is not perfect. ; )  So, to have two dads waiting and tapping their fingers would not be a good scenario. Ok, that is interesting about Brix, being more important than organic over conventional.  I've always had a hunch about that, and you'd think with all my years on the forums I would've gleaned a more concrete understanding than I have.  See, that's why I ask Jennifer .  You had mentioned Brix before...I'll look into that as time allows.  I am definitely interested in those sprouted grains, but I've had to cut back on the good stuff, due to budget.  When I go back to it, these sprouted grains are where I'll start.

Just FYI I haven't gotten the flu since atleast I was 10! So 14 years. Only type of sickness I would get is a cold after I went outside with wet hair.

why are you eating a not-varied diet in the first place

@cupofcoffee are you sure? Citrulline and arginine and beetroot boost all NO including iNOS which is what RP was against, meanwhile tadalafil boosts only eNOS (and maybe nNOS?)

@Thyrotic Hey, did you survive?

As a counterpoint, I think I've crashed my estrogen with both androsterone and 11kDHT in the past but never noticed anything with my joints because I was taking boron at the same time.

thank you all for this incredibly valuable thread. @alfredoolivas thanks for starting it. I suppose like estrogen, prolactin has its good sides. This has helped me see some more research material I would have missed that I can study.

@alfredoolivas something that could help is HUGE amounts of milk, or something else with a lot of bulk and liquid

Talk with AI (Claude) How efficient is the intake of a MK4 supplement, (with enough fat, hereby 25 g fat with some MUFAs), when taking 1 mg (1 000 mcg) K2 MK4? Question of vehicle only? No intermediate change into menadione, I suppose, since there is no digest process. Need a confirmation, whenever there is a target amount limited to 2-3 mg K2 supplement. Note: 2 takes of 1 mg MK4 at breakfast and midday meal, with 1 000 UI D3 (both at the same time, AKA 2 x 1 000 UI D3). Brain target. AI says (Claude): Summary: A moderate amount of D3 and K2 are co-absorbed in the same chylomicron pathway; so simultaneous intake is fine. Brain target and dose adequacy: 2 mg/day total is a reasonable range for a brain-focused protocol. Step 1 — Chylomicrons (intestinal phase, 0–4h postprandial) Step 2 — Chylomicron remnants → liver (4–6h) Step 3 — VLDL → IDL → LDL (hepatic re-export, hours to days) A possible route for extra-hepatic tissue supply is that part of the K-vitamins are re-packed into LDL, which forms a major transport system from the liver to peripheral tissues. ScienceDirect This is the key insight for your brain target — the liver processes the chylomicron-delivered MK4 and re-exports it via VLDL, which is then progressively remodeled into IDL and LDL for peripheral tissue delivery. Agarose gel electrophoresis of lipoprotein fractions after K2 supplementation revealed distinct chylomicron bands and variations in VLDL and HDL mobility, influenced by dietary lipids and VK2 supplementation. Wiley Online Library

COX-2 is overexpressed in advanced stages of tumors. Aspirin starts inhibiting COX-2 meaningfully after dosages of about 500mg (better would be >1g). Aspirin vindicated as an anti cancer drug. "Most solid tumors express the cyclooxygenase-2 (COX-2) protein, a target of NSAIDs. COX-2 overexpression in tumorsis considered a predictor of more advanced stage disease and of worse prognosis in a number of studies investigating solid malignancies. Therefore, NSAIDs are evaluated as anti-cancer drugs." Artificially overexpressing COX-2 makes mice more prone to developing tumors and knocking it out makes them less likely to develop tumors. "Both COX-1 and COX-2 are involved in tumor vascularization. COX inhibitors can directly affect angiogenesis [47]. " "Thus, COX-2 may be the cause of progression of estrogen-dependent breast cancer either directly by stimulating tumor cell proliferation, or indirectly by upregulating aromatase activity [60]. " "Part of the rationale for combining NSAIDs with chemotherapy involves circumvention of chemotherapy resistance mechanisms." https://pubmed.ncbi.nlm.nih.gov/16945549/ COX-2 inhibition makes chemotherapy (5-fluorouracil) more effective in vitro. https://pubmed.ncbi.nlm.nih.gov/21163769/

"Platelet COX inhibition was nearly complete already at 37.5 mg aspirin daily, as evidenced by >98% suppression of serum thromboxane B2 ..." https://pubmed.ncbi.nlm.nih.gov/16601836/

@alfredoolivas yeah im aware. Me and my son use this account. We are not on here though mainly the raypeat forum. And the reason i give him t3 is because his ATP production is bad.

skin surface way is capacitive coupling https://pubmed.ncbi.nlm.nih.gov/8200888/ this showed effect i dont have the info on their approach rn. non fusing fractures for 11+ months 6/10 fused vs 0 The non-union healed in six of the ten patients who had been managed actively but in none of the patients who had been managed with the placebo unit. https://www.semanticscholar.org/paper/Capacitively-coupled-electrical-stimulation-results-Abeed-Naseer/bc78f0db97ce86d9fc64d5487b91cee839744c8d 11 of non unions unified by 15 weeks applied through steel plates on the skin - healed if the plates were within 8cm of each other The only significant factor determining the success of healing was the distance between the plates; a distance of eighty millimeters or less resulted in healing in all cases https://pubmed.ncbi.nlm.nih.gov/8458140/ partial limb regeneration https://pmc.ncbi.nlm.nih.gov/articles/PMC4683620/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3495370/

@Ray-Peat-Fanboy no politics allowed in my Christian ray peat forum

@engineer nop sadly not

@wester130 correct. I recollect not feeling good injesting the black cumin seed extract in certain therapeutic doses

@user73636 sounded like a gimmick at first but its well studied theres a lot on it, decent amount from japan , another way to get it without a machine is buying some elemental magnesium metal sticks or ribbons (safer to avoid as fine powder tho unless stored right). can add a stick or ribbon chunk to water and it will make hydrogen bubbles (added a small amount of malic acid to speed up getting past the oxide surface and a bit more hydrogen , then rinsing after drinking. i added it without malic and it still bubbled) https://bioenergetic.forum/topic/9291/hydrogen-dissolved-in-drinking-water-or-via-gastric-acid i reckon 200ug hydrogen at once would be good. trying to figure out how much a 10cm 130mg ribbon would give. max water saturation you can get is 1mg - 1.5mg per L but it reacts slow and without a lot of acid it forms a black layer. i read some papers where they dipped it for a short time and it had effect still