Dandruff or scalp irritation? Try BLOO.

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  • Intermittent fasting may worsen diabetes type II

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  • Stanolabs DHT gel

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    Haha there’s hope for the woolly mannoths!
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    post script: I checked the spray bottle and it says in the first week of usage, you might experience skin irritation. Apply spray to damp skin whilst your body adjusts. So it must be quite common. Think I'll persist and see if it clears up.
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    KilgoreK
    Good news I have received my shipment it just took a lot longer than expected. I think the delay was due to US tariffs.
  • Im about to try to cure my SIBO/Candia

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    GreekDemiGodG
    For Candida, you need to do a biofilm disruptor + a strong anti fungal, especially If you’ve had it for many years.
  • Milk is goyslop

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    lykosL
    @Corngold all the rabbits post are straight out of chatjewpt
  • Refined beet sugar

    Products sugar beets longevity
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    @LucH I suggest reading the text about azetidine and MBP . MBP is important myeline protein rich in proline. Proline substitution by azetidine changes its function. Proline,"queen of aminoacids" is heavily produced in pregnancy. Pregnancy on azetidine could end with weaker myelin function. Gluten and caseine are good sources of proline but it requires stomach acid production and gut digestion, next -carboxypeptidase/dipeptidylpeptidase or we can have problems with glutomorphins/casomorphins. Fact-checked by Grok 4 weeks ago Carboxypeptidase A1 Carboxypeptidase A1 (CPA1) is a zinc-dependent metalloprotease enzyme primarily produced in the pancreas as an inactive proenzyme If someone would like excellent article about proline-queen of aminoacids https://web.archive.org/web/20161125195452/http://www.twoje-odzywki.pl/l-prolina_-_krolowa_aminokwasow-a-33.html https://www.mdpi.com/1422-0067/21/20/7696 The Human Digestive Tract Is Capable of Degrading Gluten from Birth[...] " **. The gastrointestinal proteases involved in gluten digestion: elastase 2A, elastase 3B, and **carboxipeptidase A1 are present from earlier stages of life" cit. "From a nutritional standpoint, brown sugar contains slightly more minerals than white sugar: about 0.50% compared to less than 0.05%. These proportions are still negligible and have no real effect on health." They are important as a prebiotic factor. Lactobacilli need zinc, manganese. Some villi enzymes require zinc. Glyphosate is zinc chelator. Polyphenols from sugar cane support Bifidobacteria. https://pubs.aip.org/aip/acp/article-abstract/3186/1/020056/3333136/The-potency-of-juice-and-brown-sugar-cane?redirectedFrom=fulltext Research Article| January 30 2025 The potency of juice and brown sugar cane (Saccharum officinarum L.) as anti-diabetic sugar based on their mineral, phenolic, and flavonoid content AI Top 10 Health Benefits of Sugarcane Juice Sugarcane juice is ... Sugarcane is a nutrient-rich, natural energy booster packed with antioxidants, vitamins, and minerals that support hydration, liver function, and digestion. It acts as a natural diuretic, promotes oral health, and provides a quick, healthy energy source while aiding in skin health and boosting immunity. Here are the top 10 health benefits of sugarcane: Instant Energy Booster: The natural sugars (glucose and fructose) in sugarcane are easily absorbed, providing a quick, hydrating, and natural energy boost to fight fatigue. Supports Liver Function: It is known to help treat liver-related issues like jaundice by balancing bilirubin levels and keeping the liver functioning optimally. Kidney Health & Detoxification: As a natural diuretic, it helps flush out toxins and infections (UTIs) from the body while supporting kidney function. Improves Digestion: The high fiber content and potassium levels help maintain a healthy digestive system, preventing constipation and soothing stomach infections. Strengthens Bones and Teeth: High mineral content, including calcium, phosphorus, and magnesium, strengthens teeth, reduces bad breath, and promotes healthy bones. Promotes Skin Health: It contains Alpha Hydroxy Acids (AHAs) like glycolic acid, which act as natural exfoliants to treat acne, prevent aging, and reduce blemishes. Boosts Immunity: It is rich in antioxidants that help fight infections, reduce inflammation, and improve overall immune system strength. Manages Blood Pressure & Cholesterol: Potassium content helps lower blood pressure, while its fiber and antioxidant properties can help reduce LDL (bad) cholesterol levels. Combats Cancer Risks: The high concentration of flavonoids and phenolic compounds gives it antioxidant, anti-inflammatory, and anti-cancer properties, particularly for prostate and breast cancer. Supports Recovery from Fever: It is known to replenish body protein loss and helps in faster recovery from viral fevers and infections. https://www.ganeshdiagnostic.com/blog/amazing-health-benefits-of-sugarcane-juice For me cane sugar/juice is like birch tree, maple tree juice. And silica is among them.
  • is my diet peaty?

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    lykosL
    @heyman i am not gooning anymore or cooming in real life femoids, my thyroid is working no need to take another supplement
  • Cooking with Jennifer

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    Potato is really underrated
  • Coffee is goyslop

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    lykosL
    @ThinPicking its not about me friendo, i do like coffee with cream milk and sugar but i still i understand its problematic longterm
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  • Humorous musings

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    DavidPSD
    [image: 1770289081040-880d5790-75cb-4f84-a209-d5bbe18c3928-image.png]
  • CGM FTW?

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    @Mossy I used to get sedated taking it on my own and in tablespoon quantities, but I now only consume it alongside food/(or milk or some other caloric drink) and only a tsp at a time. It doesn’t sedate me this way. With food, I literally just sprinkle it on top, (adds a little sweetness and not much flavor really). There’s also the possibility that it lowers stress hormones and perhaps over time I’ve lowered my stress and increased my energy such that it no longer has such an effect. Either way, try tsp vs tblspn and with food vs simply water if you haven’t already.
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    BearWithMeB
    @CrumblingCookie Retinol deficiency is very possible, but wouldn't that imply low ceruloplasmin? Mine is right in the middle of reference range (0,22 g/l)
  • Resources, but not RP

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    Dr. Bertalan Mesko, PhD, known as The Medical Futurist, is the Director of The Medical Futurist Institute. He specializes in analyzing the impact of science fiction technologies on global medicine and healthcare. As a geek physician with a PhD in genomics, he is also an Amazon Top 100 author and serves as a Private Professor at Semmelweis Medical School in Budapest, Hungary. https://medicalfuturist.com/
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    @DavidPS Thanks, there is also complementary story https://www.mdpi.com/1422-0067/26/17/8655 Ivermectin Binds to the Allosteric Site (Site 2) and Inhibits Allosteric Integrin Activation by TNF and Other Pro-Inflammatory Cytokines by Yoko K. Takada 1 andYoshikazu Takada 1,2,3,*ORCID 1 Department of Dermatology, University of California School of Medicine, Research III Suite 3300, 4645 Second Ave., Sacramento, CA 95817, USA 2 Department of Biochemistry and Molecular Medicine, University of California School of Medicine, Research III Suite 3300, 4645 Second Ave., Sacramento, CA 95817, USA 3 VA Northern California Health Care System, 150 Muir Road, Martinez, CA 94553, USA * Author to whom correspondence should be addressed. Int. J. Mol. Sci. 2025, 26(17), 8655; https://doi.org/10.3390/ijms26178655 Submission received: 1 August 2025 / Revised: 28 August 2025 / Accepted: 1 September 2025 / Published: 5 September 2025 (This article belongs to the Section Molecular Immunology) Abstract Ivermectin (IVM), a broad-spectrum anthelmintic agent, has anti-inflammatory properties, and affects cellular and humoral immune responses. We recently showed that multiple pro-inflammatory cytokines (e.g., FGF2, CCL5, CD40L) bind to the allosteric site (site 2) of integrins and activate them. 25-Hydroxycholesterol, a pro-inflammatory lipid mediator, is known to bind to site 2 and induce integrin activation and inflammatory signals (e.g., IL-6 and TNF secretion), suggesting that site 2 is critically involved in inflammation. We showed that two anti-inflammatory cytokines (FGF1 and NRG1) bind to site 2 and inhibit integrin activation by inflammatory cytokines. We hypothesized that ivermectin binds to site 2 and inhibits inflammatory signaling by pro-inflammatory cytokines. A docking simulation predicts that ivermectin binds to site 2. Ivermectin inhibits the integrin activation induced by inflammatory cytokines, suggesting that ivermectin is a site 2 antagonist. We showed that TNF, a major pro-inflammatory cytokine, binds to integrin site 2 and induces allosteric integrin activation like other pro-inflammatory cytokines, suggesting that site 2 binding and integrin activation is a potential mechanism of the pro-inflammatory action of these cytokines. Ivermectin suppressed the activation of soluble β3 integrins by TNF and other pro-inflammatory cytokines in a dose-dependent manner in cell-free conditions. Binding to site 2 and the inhibition of binding of inflammatory cytokines may be a potential mechanism of anti-inflammatory action of ivermectin.