@RandomUser I though the whole point of Haidut’s method was that the c02 accumulates and stays there after each use? So if you did it regularly you wouldn’t have to wait at all. I’ve been wanting to try it for a while now but I’ve been put off of it by having to breathe through the mouth, which I find gives me anxiety. I was wondering if anyone had experimented with adding an oxygen mask or altering the mouth of the jug to allow you to breathe through your nose instead.

I managed to get the device before the price hike and with a bit of a discount. Now I use it daily. Still just for a few minutes at about 3% of CO₂. Noticed better sleep (remember dreams better and consistently get about 7 hours of sleep). Inhaling CO₂ also helped clear my migraine. (It was a mild, albeit annoying, case of migraine.) Here is an interesting paper on the CO₂ for migraines: STUDIES ON HEADACHE1. Effects of Carbon Dioxide—Oxygen Mixtures Given During Preheadache Phase of the Migraine Attack 2. Further Analysis of the Pain Mechanisms in Headache From the Summary and Conclusions section: A series of patients were given a 10 per cent carbon dioxide-90 per cent oxygen mixture by face mask during the preheadache or early headache phase. This mixture abolished the preheadache phenomena and aborted the headache in most of the trials. Ten per cent carbon dioxide in air was less effective, having a shorter and more transient effect.

I applied her protocol when I suddenly started to have cavities in my front teeth and thinning of enamel. This came after years of no cavities at all, probably decades. I did not change anything else in my daily routine. After just a month 2 of my small cavities had completely disappeared and I did not get any new ones.

@AnomPhen Thank you so much for your advice.I also think it's hypothyroidism, My mother was recently diagnosed with it and she's taking T4.

I was able to aquire fenclonine from a regular chemical supplier, same goes for all the other chemicals aswell. Its not hard you just have to jump through the hoops they give you and then they dont care.

*) Useful nutrients for thyroid: Se I Zn Mg and Fe for enzyme TPO Selenium (Se), Iodine (I), Zinc (Zn), and Magnesium (Mg) are vital trace elements and minerals that support thyroid hormone synthesis, conversion, and cellular regulation. [1, 2, 3] Roles of Each Nutrient • Selenium (Se): Powers the enzymes (deiodinases) responsible for converting inactive T4 into active T3 hormone, and acts as an antioxidant protecting the thyroid from oxidative damage. [1, 2] • Iodine (I): Acts as the fundamental raw building block required by the thyroid gland to manufacture T4 and T3. [1] Never take an iodine supplement, without staples and after all without having first replenish with selenium. Follow a protocol to avoid a backfire. • Zinc (Zn): Assists the brain in sensing hormone levels, supports T4-to-T3 conversion, and helps thyroid hormones bind to cell receptors. [1, 2, 3] • Magnesium (Mg): Aids in overall energy production, helps regulate and lower elevated TSH levels, and supports cellular hormone activation. [1, 2] Useful nutrients for DIO enzymes Here is the chronological, step-by-step story of how thyroid hormones are handled by the body. Written with help of AI (ChatGPT) to set in order. The Normal State (Euthyroid) In a healthy, nutrient-replete body, the thyroid axis operates like a well-oiled factory: The Factory Line (Thyroid Gland): The thyroid gland extracts Iodine from the blood. Using the enzyme Thyroid Peroxidase (TPO), it binds iodine to tyrosine to manufacture T4 (about 80–90%) and a tiny bit of T3 (about 10–20%). [1, 2, 3, 4] If you don’t live near the seacoast (< 50 Km) and don’t eat fish or seafood you lack iodine. NB: Woman's breasts and a man's prostate will not receive much of this iodine, as it is primarily sequestered or diverted by the thyroid. Guess now what kind of risk that entails… The Shipping Yard (The Bloodstream Pool): The thyroid dumps these hormones into the blood. The T4 travels throughout the body as an inactive storage hormone. To make the blood pool rich in active T3, the liver and kidneys use DIO-1 enzymes to convert T4 into T3. This liver/kidney conversion accounts for 80% of the active T3 floating in the blood pool. [1, 2, 3, 4] The Local Customers (Muscles & Tissues): Skeletal muscles pull what they need from two sources to maintain a 50/50 balance: o 50% is absorbed directly as pre-made T3 from the blood pool. o 50% is absorbed as T4, which the muscle internally converts into active T3 using its own DIO-2 enzymes. The Power Plant (Mitochondria): Once inside the muscle cells, T3 binds to nuclear receptors, ordering the mitochondria to produce ATP (energy) and heat. Magnesium acts as the essential spark plug required to synthesize and utilize that ATP. [1, 2, 3, 4] Remember that magnesium is used by at least 360 enzyme reactions, as often mentioned. Current enzymatic databases have identified over 600 enzymes that require magnesium to function, plus another 200 that need it for activation. [1, 2] To summarize one caveat (for me, LucH): The whole thing (+/ 85%) depends on T4 formation, depending on iodine and the enzyme TPO. Here we have hit the exact nail on the head. No matter how much selenium, zinc, or magnesium a person takes to optimize their conversion enzymes (DIO-1 and DIO-2), those enzymes are entirely useless if they have no T4 raw material to work on. And as we noted, T4 production depends entirely on the availability of Iodine and the functionality of the Iron-dependent TPO enzyme. When taking a synthetic T4 supplement for thyroid, individuals often feel better and improve their energy level but it doesn't last because of a lack of cofactors. Depleted Reserves: An initial dose of T4 provides a temporary boost. However, it quickly depletes your body's existing nutrient reserves, stalling the conversion process and causing symptoms of fatigue to return. [1, 2] Master Post: Why Your Thyroid Medication Fails Without Cellular Cofactors Many thyroid patients—especially those taking synthetic T4 (Levothyroxine) or T3 (Cytomel)—experience a frustrating paradox: their blood work looks perfect, but they still feel exhausted, cold, and weak, again, if we leave aside the temporary improvement. The reason? Tissue-level hypothyroidism. Taking synthetic hormones is only half the battle. If your body lacks the specific nutritional cofactors required to manufacture, convert, and absorb those hormones, the medication simply floats in your bloodstream completely useless to your cells. Here is the step-by-step chronological story of how thyroid hormones travel through your body, where they get blocked by deficiencies, and how to fix it. Step 1: The Factory Bottleneck (T4 Production) Before a single drop of active hormone can be used, the thyroid gland must manufacture T4. • The Process: The thyroid gland uses an enzyme called Thyroid Peroxidase (TPO) to bind Iodine to tyrosine. • The Required Cofactors: Iodine and Iron (Fe). TPO is a heme-dependent protein, meaning it literally requires iron as its structural engine. • The Failure State: If you lack iron or iodine, the factory shuts down. Vegan Caveat: Because non-heme (plant) iron has a very poor absorption rate, vegans are more likely to suffer from a TPO factory shutdown. If your body cannot produce or process T4, the rest of the downstream system collapses. Step 2: The Shipping Yard (Systemic Blood Conversion) The thyroid gland's direct output is roughly 80–90% inactive T4. To create the pool of active T3 in your bloodstream, your liver and kidneys must step in. • The Process: The liver and kidneys use DIO-1 (Deiodinase-1) enzymes to strip an iodine molecule from T4, turning it into active T3. This creates 80% of the circulating T3 pool in your blood. • The Required Cofactor: Selenium (Se). DIO enzymes are selenoproteins made of selenocysteine. • The Failure State: If you are deficient in Selenium, DIO-1 fails. The pool of active T3 in your bloodstream dries up. NB: When the body faces an overload of toxic metals or a depletion of its antioxidant reserves, available selenium is consumed in large quantities to neutralize these stressors, potentially leading to an induced deficiency affecting other vital functions (such as thyroid hormone synthesis). RDA: Approximately 70 µg/day for an adult. 100 µg as a course of treatment, but not daily—except in specific cases. Too much of a good thing becomes bad. ️ Step 3: The Local Deliveries (Skeletal Muscle Conversion) Your muscles require massive amounts of energy, maintaining their internal T3 levels via a 50/50 balance: 50% is absorbed directly as pre-made T3 from the blood pool, and 50% is converted locally inside the muscle from T4. • The Process: Muscles pull inactive T4 from the blood and use DIO-2 enzymes to convert it into active T3 on-demand. • The Required Cofactors: Selenium (Se) and Zinc (Zn). • The Failure State: When blood T3 is low, muscles try to compensate by increasing DIO-2 activity. But if you lack Selenium, the muscle cannot build the DIO-2 enzyme. The backup plan fails. The unconverted T4 shunts down the path of least resistance, turning into Reverse T3 (rT3)—an inactive molecule that blocks your receptors and worsens fatigue. Step 4: The Cellular Gatekeepers (Receptor Binding) Once active T3 finally arrives at your cells, it faces a locked door. It must bind to the Thyroid Hormone Receptor (THR) inside the cell nucleus to deliver its metabolic message. • The Required Cofactors: Zinc (Zn) and Vitamin A (Active Retinol). Zinc forms the structural "zinc fingers" of the receptor so the hormone can fit the lock. Vitamin A allows the receptor to successfully talk to your DNA. • The Failure State: Without Zinc or Vitamin A, the receptors deform. T3 is completely locked out of the cell. You remain symptomatic even if your blood levels are flooded with T3. Step 5: The Power Plant (Mitochondrial Spark) Once the message successfully passes the gatekeepers, the cell commands its mitochondria to generate energy (ATP) and heat. • The Required Cofactors: Magnesium (Mg) and Iron (Fe). • The Failure State: Magnesium is the ultimate spark plug required to synthesize and utilize ATP. Without it, you experience profound muscle fatigue, weakness, and cramps. Furthermore, a lack of magnesium impairs the pituitary gland, frequently driving TSH higher. ️ The Action Plan: How to Fix the Gaps To ensure your thyroid therapy actually reaches your cells, target these specific dietary fixes: 🥩 For Omnivores: The Ultimate Thyroid Superfood Dietary sources such as poultry liver provide nutritional compounds containing bioavailable iron, zinc, selenium, and pre-formed vitamin A. For Vegans & Poor Converters (The Vitamin A Trap)* Many people over 45 years old possess a genetic slowdown that allows them to convert only about 15% of plant-based beta-carotene (from carrots/sweet potatoes) into active Vitamin A. Vegans cannot eat liver to bypass this. • The Protocol: Supplementation with retinyl palmitate is sometimes utilized under professional guidance, often taken with dietary fats to assist the absorption of fat-soluble nutrients. LucH says: I would advise them to take 5000 UI Retinyl palmitate twice a week. At breakfast with some fat. Essential Cofactors Needed for T4-to-T3 Conversion • Selenium: A vital mineral and enzymatic cofactor required to manufacture thyroid hormones and assist in conversion. [1, 2] • Iron (Ferritin): Low iron storage impairs the enzymes responsible for activating thyroid hormones. [1, 2] • Zinc and Copper: Critical minerals that support the deiodinase enzymes responsible for turning T4 into T3. [1] • Vitamin D and B Vitamins: Necessary for cellular energy production, immune regulation, and proper hormone receptor function. [1, 2, 3]

@Jennifer You're welcome.  I can't help but reference these authors that have been such an influence on my me.  I stress again, I know everyone is different, in that the paths we've been on have us favoring different voices and styles, though I believe truth is truth, which survives above style and preference.  At the least, a truth discovered, even from an author who is not preferred, could lead us deeper into a subject, searching out an author we do prefer, who speaks to us better.  I do like archive.org.  I used to use them quite a bit, but then I got spoiled with how cheap some ebooks have become, and how the formatting allows for ease of use.  But, I will give this to the PDF format, you get the images of the original pages of books, which gives you some of that physical book quality, which can't be replicated in a full digital format.  I actually used to prefer the PDF for this reason, but now I can't resist the ease of full digital format.  Though, I will still go to archive.org for books not yet available as an ebook. Your religious history is very common, having touched upon various aspects of Faith through family, and educational institutions.  That's all of us, really; which is Lewis's story as well, until he became fully immersed. I do like the Alexandre brand very much.  I think there is hardly a better brand available for dairy, at least at a chain store.  Kalona is a good brand too, but like Alexandre, expensive.  Okay, so Nounos is cheaper, comparatively. So, you were basically making Greek yogurt from the regular versions, by straining it?  I never thought to do that, but can definitely see how that is costly. Yeah, stress is brutal on our health.  I can see how your mother's passing was hard.  Interesting, but kind of understandable, how plant-based foods were hard on your thyroid. When I was at my worst, raw foods were hard on me.  Maybe my correlation is off, but the strong natural defenses of plants, and especially with raw, seem the culprit.  Though, even as I type this, I remember raw juices made me feel good.  Maybe the juicing broke down those defenses.  This is my bro-science ...something worked by juicing them!  I have tried olive oil based D3.  A very lean version, with the only ingredient listed besides the D3 (cholecalciferol) being olive oil.  And strangely, I still had issues with it.  I've tried so many different versions. I forget which was the most temporarily tolerable — which is the only possible scenario for me.  I can take nothing long term, and I really can't remember a vitamin D supplement that didn't make me sick for at least a week...haha.  Funny stuff.  I may go back to putting mushrooms out in the sun, but there isn't really a way to know the true potency, though it would still be more than I'm getting.  Most of all, though, it would be costlier and more time consuming.  Maybe Haidut's is worth another try (if he has a non-ethanol version). Funny.  My only claim to being partially Italian is the claim itself (apart from my ancestors proving it): I don't think anyone would ever call me Italian by looking at me.  I like butter as well; even better than olive oil.  In most recipes, if I can use butter instead of oil, I'll do it.  But, right on cue, since I've started making banana bread, I've switched to coconut oil, and it is more moist.  From my limited experience, your mother is correct!  My understanding of olive oil is that you want a single source, cold pressed, and minimal time from harvesting, to manufacturing, to consumer.  This would eliminate, seemingly, as much potential for unwanted variables as possible.  It seems olive oil imported from outside the US is very subject to being something other than what is stated.  When I was researching this about a year or so ago, there were reports that the oils were not necessarily what was being claimed on the bottle, for non-US oils.  There were claims they were mixed (i.e., contaminated with lesser or other olive oils); and if not that, prolonged storage and transit was reducing the quality.  But, these days, who knows about the oils in the US.  My rule of thumb, is you do your best research, then just go with what you have have access to, and don't worry after that.  As for the 100% CA oil, it can be costly, but I only buy it on sale.  I normally use the Amazon brand, which is cheaper than the other popular, 100% CA brand (California Olive Ranch).  Olive oil is the one food item I consistently splurge on.  I splurge because of the potential rancidity of oils and other negative factors.  But, should my budget get even tighter, I'd simply buy a cheaper oil and not worry about it; though, always olive or coconut oil, not soy, canola, etc. It's worth adding, that even though the olive oil is a higher quality, it doesn't make the best tasting mayo, by itself. My understanding is that the blending breaks the fragile EVOO and makes it a bit bitter. I counter this by putting a little sugar in it.

@chudlord there's one thing i disagree with you about - the safest oral AAS, i think it is this Oral Primobolan (Methenolone acetate) Not 17α-alkylated (protected by 1-methylation). Low hepatotoxicity. Non-estrogenic, low androgenic activity. Produces slow, lean gains with few sides. Expensive and modest in results. Injectable form is even milder on the liver. Frequently ranked among the safest for health-conscious users.

@alfredoolivas hahahaha

I tried livagen (or whichever the liver one is) can’t say I noticed anything, (like better glycogen storage or more working capacity before dipping into stores) but that said, those versed in the stuff say you won’t really “feel” it. I think before trying anymore I’d want to research some markers and do some before and after testing, (otherwise I think it’s kinda on faith). Just my experience

@jamezb46 is it not more likely that this is merely increased excretion rather than increased absorption?

@lobotomize Good framework, though the evidence-grade weighting in the default sort might bury solid animal/mechanistic work under mediocre human studies. Letting people re-weight it themselves could help. Bigger gap: how do contested claims get handled? If a newer RCT contradicts an older one, does the old card get flagged/archived, or do they just sit side by side? That seems like the whole point of avoiding rediscovery. Also worth adding a required sample size field to the submission template — two "Evidence B" studies can carry very different weight depending on n, and that gets lost if it's folded into the letter grade alone. Export for meta-analysis is a nice touch though.

I got some camu camu powder today and put 1/4 tap in some OJ and the effects are nice. Calming energy. And seems to perhaps prevented this late afternoon histamine release I get sometimes. I live in one of the worst cities in the world for seasonal allergies. I will continue with the smaller 100mg doses.

https://www.youtube.com/watch?v=UnPMoAb4y8U https://www.youtube.com/watch?v=GtPD0sAhCUo https://www.youtube.com/watch?v=Fa0E7A2EGKQ

@Peat-OPeat-O Pregnenolone being the "mother hormone" gives you more buffer than something more downstream/receptor-active. That said, I wouldn't treat any specific numbers in this thread as a fixed protocol. Response varies a lot person to person depending on thyroid, liver clearance, existing hormone levels, etc. If you're totally new, I'd start smaller than anything mentioned above, go slow, and ideally get some baseline labs so you're not just going off how you feel. Source quality matters too, worth doing some digging before committing to a supplier long-term.

@PrinceTrebata If you mean which has the least contaminants, nobody knows 100% for sure. In a recent thread on the issue somebody recommended Zen Principles brand to me saying that of all the brands they queried about heavy metal contamination theirs had the least. https://bioenergetic.forum/topic/3063/gelatin/9

Does anyone know what type of B1 Peat recommended? HCL? He never seemed to specify.