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  • shuz the website down

    Bioenergetics Discussion
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    lobotomizeL
    @alfredoolivas damn that deep. never thought about that. have you thought about signing up to think as a professional thinker?
  • Humorous musings

    The Junkyard
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    DavidPSD
    [image: 1771417636030-c9af89fb-ce9d-4abd-858c-73382b3c71a6-image.png]
  • 0 Votes
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    ThinPickingT
    @gg12 said in Using the internet may be very bad for your mental health: Even if its something I agree with. The internet just feels like escapism for me. You can only work on your capacity to weather disagreement irl gg. Which includes anything you read, see or hear. https://bioenergetic.forum/post/56473
  • 11KT - 11-keto-Testosterone

    Products
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    42 Posts
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    MauritioM
    @wester130 I thought it was interesting. Because if it was just some "adrenal stress hormone" as some will surely dismiss it as, it probably wouldn't peak during the time where people generally are the most healthy.
  • 2 Votes
    14 Posts
    198 Views
    KilgoreK
    Why are you attacking me? Jokes aside that is probably true. Also huge percentage of trannys. Technically I have Asperger syndrome (diagnosed).
  • Cynoplus sources in US

    Products
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    7 Posts
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    E
    @Chud said in Cynoplus sources in US: @Ecstatic_Hamster did you recieve it? I did. All good.
  • Using AI to summarize a YouTube video

    Current Events
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    I’ve been enjoying getrecall.ai. Worth the money.
  • Sudden dental issues/lack of saliva

    Not Medical Advice
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    JenniferJ
    @happyhanneke, I searched through Ray’s radio interviews addressing cavities and all I’m finding for potential causes are low thyroid, excess estrogen, stress, poor digestion and poor saliva production. Some examples: Question: We've got another question here on dental health. Question about there's a lot of people who recommend eliminating sucrose, fructose, and most fruits when people have dental ailments. And on the other side of it, you know, you talk about increasing, you know, carbohydrates, you know, for cell metabolism, et cetera. Can you elaborate a little bit on that, why there's so much conflicting information on that, and what contributes to dental issues? Ray Peat: I saw a recent article on dental health in Sweden, and they saw that during the time that cavities have decreased radically, sugar, candy, and soft drink consumption had actually increased, and they couldn't account for why the teeth were healthier while they were -- the basic diet hadn't changed so much, but had increased in the supposedly cavity-causing snack foods. And in my sugar article, I mention some of the old studies in which they modified the thyroid or estrogen and found that increased estrogen increased the dental decay, increased thyroid reduced the dental decay. And one whole line of dental research has shown that stress will very quickly cause an outbreak of cavities. And mainline dentistry just thinks in terms of germ growth in the mouth and completely neglects the chemical and immunological function of the saliva. I think the saliva is the mediator of stress. https://bioenergetic.life/transcripts/88db6?t=4785&c=109 Question: Now, do you think that a lot of our digestive distress is from a kind of a society of sitting? Ray Peat: Yeah, definitely. Everyone who takes up the habit of walking for an hour or so a day notices improved digestion. The general sense of well-being is largely because of the improved movement of the intestinal muscles but also improved secretions. Feeling good and relaxing and moving around reduces the nervous tension and that increases the secretions. You can see it even in saliva. When you're very anxious, your mouth tends to go dry because of the shift from one part of the nervous system to the other shuts off secretions starting in the mouth but affecting all the way down. Question: Yeah, so there is kind of a north to south process, right? So, would you say that the saliva is just as important as the stomach acid? I mean, as it starts there and it works down to the stomach acid and then the CCK and all the different secretions that happen from the pancreas and the liver. Is it pretty important to start with the fundamentals like keeping a good cephalic head phase of digestion going as well as good adequate stomach acid? Ray Peat: Oh yeah, anyone who has taken a drug that shuts down saliva production has generally had an outbreak of cavities. The anti-cholinergic drugs and some of the anti-histamines reduce the production of saliva so much that it's not just the drying of the lower quantity of saliva but the composition changes chemically. Instead of washing away and inactivating bacteria and their products, it tends to favor their growth. So, you can see it as increased deposits on the teeth but especially in the extremely fast development of cavities when the mouth is dry. https://bioenergetic.life/transcripts/13b78?t=382&c=8
  • Not all sirtuins are bad? (SIRT3)

    Literature Review
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    No one has replied
  • 2 Votes
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    184 Views
    MauritioM
    @wester130 That's not the one that I use. I would make sure it's food grade .
  • Resources, but not RP

    Ray Peat Resources
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    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/
  • Songs you like

    The Noosphere
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    L
    @Uncover based and beauty pilled
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    60 Views
    alfredoolivasA
    @Maximalus Chill. When buying candy online be used to long delivery times
  • Cooking with Jennifer

    The Kitchen
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    JenniferJ
    @Mossy, in fairness, I had a sick mum while growing up that I took care of, as well as my grandparents, and I worked in childcare for two decades so I have years of experience. I think you’re doing a great job. Our dads sound similar. Mine tells me he doesn’t need a lot of options, but after several times of making meals he said he wanted in the rotation, some taking upwards of 2 hours to make a large batch of, and having them sit in the freezer untouched because he changed his mind, I had him give me a definitive list of meals, and I stick to it. I’m impressed you made quark. I used to make raw butter, mesophilic yogurt, kefir and curds, but never attempted quark. Regarding the fries—I was doing the same until I came across fries at Whole Foods that are cooked in tallow. Because I had so much on my plate after my mum died and a thyroid that was no longer responding to supplementation, I had to make compromises for my health, and this is one of them. They’re pricy, but frequently on sale so I stock up. My dad has a burger once a week with fries and gets roughly 3 servings per bag so even though I was making them fresh for less, the convenience has been priceless. They take 14 minutes in the air fryer to bake and my dad said that they’re not quite restaurant quality, but are much better than other frozen fries on the market that he’s had. In case this is helpful, these are the fries: -https://www.jesseandbens.com/fries/p/tallow-sea-salt It’s a nice location, for sure. I live in the most forested region of the country so nature is abundant here, but we got lucky with this property being only 5 minutes from a town with full amenities and 10 minutes from the city. We don’t have access to a guava orchard like you, though. Sorry for my confusion regarding your compost heaps. Hügelkultur doesn’t require digging, but I wonder if a raised garden bed like the galvanized style (Birdies brand?) would deter the cats? I live on 5.5 heavily wooded acres where fencing proved useless so until I can build my dream greenhouse (one large enough for an orchard that’s heated using passive solar—visual-light-transmitting fiberglass tanks), I grow my plants in large garden boxes on my back deck. Ah…I see. Your dad is the foreman. My dad tried that with me and quickly regretted it. lol Unlike your dad, mine is still physically capable.
  • 1 Votes
    2 Posts
    75 Views
    DavidPSD
    @AlphaZance Thanks Treatments of old neurons with energy precursor and Nrf2-inducer restored GTP levels and size of vesicles in both genotypes. A Free/bound GTP levels (a) and bound/free GTP levels (b) in untreated old age (20 months) nTg neurons. Treatment of old age (23 months) nTg neurons increased the free/bound GTP levels in the cytoplasm and dendrites (c) and reduced the bound/free GTP levels (d). B In untreated old age (26 months) 3xTg-AD neurons, free/bound GTP levels (a) and bound/free GTP levels (b). In old age 3xTg-AD, the decay observed in free/bound GTP levels was restored to basal levels with combination treatment (c), reducing the bound/free GTP levels (d). Red arrows indicate accumulation of vesicles in both genotypes. C Treatment restored the free/bound GTP levels in old age nTg neurons. D In 3xTg-AD neurons, combination treatment prevented the decrease in free/bound GTP at middle and old ages. Each point is the mean of 7–10 fields from each mouse culture (N cultures). E A large increase in vesicles with bound GTP was observed in old age in both genotypes. Different lowercase letters and numbers indicate significant differences (p < 0.0001) after Tukey correction for multiple comparisons. F, G Treatment with nicotinamide and EGCG combination reduced the number of bound GTP vesicles in old age neurons in both genotypes (nTg: young 2 months and old 24 months; 3xTg-AD: 2 months and 18 months) [image: 1771192669693-a36d9d08-6f56-4545-889c-19b5359325ce-image.png] Treatment of age-related decreases in GTP levels restores endocytosis and autophagy (2025)
  • 1 Votes
    32 Posts
    3k Views
    DavidPSD
    The Effect of Ergothioneine Supplementation on Cognitive Function, Memory, and Sleep in Older Adults with Subjective Memory Complaints: A Randomized Placebo-Controlled Trial (2025) Abstract Ergothioneine is a diet-derived antioxidant with emerging evidence of neuroprotective benefits, but no dose-ranging study has evaluated its effects in healthy older adults. In this 16-week randomized, double-blind, placebo-controlled trial, 147 adults aged 55–79 with subjective memory complaints received ergothioneine (10 mg or 25 mg/day ErgoActive) or placebo. The primary outcome was the change in composite memory (CNS Vital Signs). Secondary outcomes included other cognitive domains, subjective memory and sleep quality, and blood biomarkers. At baseline, participants showed slightly above-average cognitive function (neurocognitive index median = 105), with plasma ergothioneine levels of median = 1154 nM (interquartile range = 889.9). Plasma ergothioneine increased by ~3- and ~6-fold for 10 mg, and ~6- and ~16-fold for 25 mg, at weeks 4 and 16, respectively (p < 0.001). 25 mg ergothioneine showed a within-group improvement in composite memory at week 4 (p < 0.05), although this was not sustained. Reaction time improved in both groups, dependent on time. Other domains showed null or limited effects. Subjective prospective memory and sleep initiation improved dose-dependently, with significant effects at 25 mg (p < 0.05). Liver function improved and a within-group increase in telomere length was noted. In conclusion, ergothioneine supplementation was safe and well tolerated, with evidence suggesting some benefits in this cohort of healthy older adults. Longer trials in individuals with lower baseline ergothioneine or cognitive function are warranted. [image: 1771192596623-4ac86e7b-a668-461a-adad-aa8891d4c572-image-resized.png]
  • 0 Votes
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    21k Views
    W
    "In reference to the man who fell in a fireplace and regrew his hair - you can actually get your scalp skin burned off. It is called a phenol peel, far stronger than an ordinary chemical peel. It is not sold online, you cannot buy the ingredients, only specialist beauty centers will offer it."
  • is juice from concetrate good

    Bioenergetics Discussion
    7
    1 Votes
    7 Posts
    112 Views
    LucHL
    @cyberpeater22 said in is juice from concetrate good: No, why? You asked for advice and afterwards you became suspicious, not to say more. The same behavior ...
  • PEATSPHERE is dysgenic

    Bioenergetics Discussion
    79
    -3 Votes
    79 Posts
    9k Views
    UncoverU
    you aren't thinking coherently or logically. your logic is flawed and biased, just my 2c. Hope you would rethink this biased emotional behavior controlling you, it would benefit your future greatly.
  • Colostrum Source EU

    Products
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    UncoverU
    @Gamma I think you could contact shipping forwarding services where you ship to them and they ship to you, if you ask them then maybe its possible for them to add new ice before shipping to you and this would allow you to buy raw grassfed frozen colostrum from USA and many other countries. I was thinking of doing this myself. It would also be ideal if the service can ship it fast to your country aswell ofcourse