@Ecstatic_Hamster Appreciate the input, Hamster. Yes, I think you are correct, about losing weight that fast. I have no arguments there. But, in my brother's case, he would've lost his life anyway, had he not made any changes. He had to have emergency medical intervention to save his life. That was a turning point for him. He went hard in one direction, and just hung on to life, and now is going hard in what he sees as the best direction, based on the results. I sense after the shock of an emergency situation, and now the weight correction, he may come back to the middle. Those stats you provide are interesting. Am I missing the obvious, or is it being claimed that as little as a 10.5% decrease in BMI, over a 2.2 year span, caused an increased risk of all-cause morality? I'm not saying it's not true, I'm just surprised by those numbers. Arguably, an over weight person could have other troubles by not reducing at least 10.5% BMI, it would seem.

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@Milk-Destroyer, I understand. They used to be one of my least tolerated foods when I had chronic SIBO and subsequent gastritis. Along with bloating, they caused brain fog, depression, hypoglycemia, reflux so bad that I woke nightly choking on acid, and tonsil stones the size of pinto beans, which Ray said were white blood cells from an immune response. All foods but fruit were problematic back then. I actually developed anaphylaxis to dairy, and I grew up on a dairy heavy diet.

@cookielemons Only 2 minerals are used in bone mineralization: calcium or phosphorus. As metabolism decreases, bone mineralization via phosphorus increases. For a brief correlation: older people have a higher phosphorus to calcium ratio in the bones than young people (who have higher calcium in the bones), and older people also have more bone fractures than young people. For the amount of phosphorus naturally occuring in the diet, it's actually pretty hard to balance it on a 1:1 parity with calcium, which is a way more important balance than with magnesium. High dietary calcium does not cause a problem, you urinate out excess. PTH causes all kinds of problems with calcium metabolism, tho. PTH raises when dietary calcium is low, and this forces calcium rich tissues to dump calcium into the blood, and for calcium uptake everywhere. It's an emergency response and redistribution by the body because of how vital calcium is for metabolism and the heart. If dietary calcium is not present, supplemental vitamin D can place higher demand on calcium, which will raise PTH to get it, and this cause the afformentioned problems. This is not Peat's crazy ideas he just made up. I can't remember the Japanese researcher, but he got a nobel prize for his research on calcium metabolism. Peat referenced his work. Peat is on the ball with calcium metabolism. While it's totally possible to be so low in magnesium, and metabolism be so retarded, you could possibly cause problems, it's possible you just weren't eating magnesium rich foods. Kidney stones are actually created by elevated PTH -- this is paradoxically caused by low dietary calcium. Toying with mineral balances is mostly what it sounds like: playing wackamole -- because minerals can never be regulated effectively until thyroid is addequate. the body doesn't feel the presence of a high calcium food and go "oh no, need more magnesium." Storage, utilization, and/or discarding of nutrients, is a constant automatic process. Either the metabolism is functioning to do this, or it's retarded. hand-selecting the nutrients to attempt to bypass this has little basis in reality as far as I understand it. Sodium and calcium are the only minerals you really have to conciously consume in accute weigh-able amounts, the rest come from a nutrient dense diet. They function like a chemical, directly impacting physiological processes. Sodium turns off aldosterone, a vasoconstricting hormone. Calcium lowers PTH, a calcium leaching hormone. Both of these are stress hormones. Between coffee, milk, OJ, oysters, and liver, you should hit your other mineral intakes decently well.

Update I'm feeling just fine again at rest like before taking the thiamine. Hooray!

@LucH said in Limit blue light with a software?: For what wavelength does lutein provide protection? Same question for blue light. => Lutein, zeaxanthin, anthocyanin. [image: 1772481782012-addf12df-1d7f-41e9-944c-194a4424c2d4-image.png] https://healthjade.net/what-is-lutein/ https://www.mdpi.com/2072-6643/13/9/3239#

@lobotomize - Thanks, another reason to proceed with caution.

You’d better listen to the signals of your body and accept them. Perhaps temporally though the body has memory (immune system). Perhaps not yet too late if you are very cautious with dairy. Nothing to do with lactose intolerance. 50 % intolerant with gluten are intolerant to milk. Mimicry. We don’t need dairy to get the appropriate amount of calcium even if it’s easier or if you like it. E.g. broccoli is very rich in available calcium. You don’t need 1200 mg calcium. The amount 550 or 850 mg Ca depends on how you deal with the acid-base balance (Na, Ca, K, Mg versus Phosphorus and Sulfur). To help balancing you’ll probably need: bisglycinate magnesium phophocalcium (+ calcium citrate when there is oxalate in veggies) potassium bicarbonate. I track my balance with cronometer.com (I’ve changed the targets). I repeat: you can’t force the body to accept sth when the intestinal linen are fragile / irritated. The sooner you accept it (100 % or it won’t never heal completely), the quicker you can get / optimize the tightness of the brush border of the stomach. I can give a link if interested, if you accept the fact you won’t heal “over the next 2 weeks”! To optimize the motility, get inform on MMC (interprandial motility). But you’ll probably need to heal the integrity and the thickness of the stomach linen before adding fibbers (with glutamine). A last advice: If you wait too long, you’ll get problem with the microbiota and perhaps / probably with candidiasis. There, no glutamine advisable or you’ll feed the beast. Act before you suffer from SIBO/ SIFO too much to tolerate what you can eat. Much more restrictive then. See my answer here to Samyo: Key information for SIBO / SIFO https://bioenergetic.forum/post/50601

@gg12 fix your liver, then your gut it appears you are not storing glycogen well, thus the stressed state, insomnia, intense cravings for carbs - quite similar effects to ketogenic diets/excessive fasting. Caffeine has a half-life of 5-6h, thus coffee before 2pm shouldnt interfere tremendously with sleep onset unless dealing with insufficient metabolic adaption to it (u can think of coffee putting your metabolic engines on 110% overdrive). It certainly will do you harm in the long term especially due to it ramping up FFA, Cortisol and perhaps exacerbating gut issues. Haidut has many posts regarding why prolonged Lipolysis = very bad Usually one adapts to coffee intake within a week, make sure to always side it with milk (since lactose-intolerant, mayb try gelatin), sugar and a meal (Theanine and B3 can help too). I like Affogatos. Keep somehwat of a steady glucose intake/well balanced meals thereafter. If you still crash by the end of the week try tea and focus on gut & liver health first Also consider Caffeine and CYP1A2 detox pathway as this, high estrogen and/or taking drugs/supplements that bind to the CYP enzyme (e.g. aspirin, quinolone, or phytonutrients like curcumin or polyphenols) might be another factor of heightened caffeine sensitivity / liver issues

@cookielemons I was eating a shit ton of them, probably 0.5 kg every evening, but yeah, I agree they were not my only issue back then

I have had the same issue with not just B vitamins but also any pro metabolic supplement like pyrucet. The trick is to both take the vitamins with lots of carbs and to also increase carb intake in the hours after, since your glucose oxidation will be ramped up and your blood sugar will plummet easier, leading to the fatigue you describe.

https://pubmed.ncbi.nlm.nih.gov/40628952/ https://bioenergetic.forum/topic/167/improving-eyesight

@engineer The surplus comes from grannies I think my dopamine/serotonin ratios and amounts itself aren't the issue, but rather dopamine tone/receptors are INHIBITED probably by higher serotonin/its receptor signaling Direct dopaminergic stuff like coffee/concentric exercise/carbs/protein/light don't improve the post-olanzapine anhedonia/other symptoms even 0.1% NO CHANGE at all So something is rewired, inhibiting brain centers related to pleasure/sense vividness Keep in mind I only got this AFTER olanzapine My nutrition/lifestyle was the same before The drug changed something and it isn't going away on its own so far

Another quick update. Just took a shower and removed a large quantity of earwax from my left ear. My left TMJ feels much better now, though not completely. I might go to an ENT in a month to get a professional ear cleaning. Even if you can hear, you could have earwax that is affecting TMJ symptoms.

Soon to be replaced by the Open AI brain chip. Zog planted right in your gray matter.

Dihydromyricetin in the management of diabetes and its complications: a narrative review Managing diabetes mellitus (DM) and its long-term complications remains a major global health challenge. Dihydromyricetin (DHM), a natural flavonoid abundant in Ampelopsis grossedentata and Hovenia dulcis, has attracted increasing attention for its multi-target anti-diabetic properties. Growing evidence indicates that DHM improves glucose metabolism, alleviates oxidative stress and inflammation, regulates autophagy and cell death, and exerts beneficial effects in DM and a range of related complications, including diabetic nephropathy, cardiomyopathy, cognitive impairment, and wound healing impairment, and other related complications. Overall, this review provides an overview of preclinical research on DHM in DM and its main complications, emphasizing its therapeutic benefits and underlying molecular mechanisms.

@Luke said in Songs you like: @Jennifer said in Songs you like: @luke What luck! I forgot about football, but I did think of The Sopranos. I thought if it was featured in an episode I’d get a pass, but I checked and it wasn’t so I went for nostalgia, figuring you and I are close enough in age that you probably grew up hearing it, too. The song I posted on the previous page (Don't stop believin') is the most famous and last song featured in Sopranos. I have never watched that Johnny Depp movie from 500 miles song, though. Looks like fun. https://www.youtube.com/watch?v=TPzU1Uz8ujw They chose a great song. It’s one of my favorites. I haven’t seen Benny & Joon either. It does look fun. The characters seem endearing.