dont participate

@mpmh other than Ronaldo, no. 99.9999999% of everyone else are coping also >high level athlete >hansius kekw

@sunsunsun I should call her

@CrumblingCookie - I do not know; but here is my guess. The first and last authors both work at "Laboratory of Extracellular Matrix Regeneration, Institute of Translational Medicine, Department of Health Sciences and Technology". Longevity is not within the Institute's purview. They reported the increase in longevity with the additional glycine but they did not expand on their findings. Similarly, at the bottom of page 4 of the PDF there is a section entitled "Synergistic longevity by combining α-ketoglutarate and 3 Gly : 1 Pro : 1 Hyp". Synergistic longevity may be outside the Institute's purview.

@CrumblingCookie Haven't tried it but it is available! Just a head's up that I tend not to talk on this forum about mere possibilities or random pipe dreams that occur to me. You can order from England: https://www.predatornutrition.com/us/testosterone-boosters/fusion-supplements/atd.html

@sunsunsun maybe? It might be a stretch but I knew people in college and/or family members in that time period had warts on fingers or feet, and I suspect that that does tie back to moving away, life transitions, stress, etc. I haven't had any warts since 20-21. I think it's nutritional and hormonal too (in absence of any formal theory). The one on my foot began to hurt, and would keep "coming back." There are definitely bacterial infections and stuff too, which can be treated. If it's fungal then maybe baths or daily environments are hosts for black mold or other mold?

@lobotomize drinking 8L of milk a day increases serotonin, yet here we are.

Apigenin inhibits xanthine oxidase so it can raise atp and lower uric acid.

I'm just seeing this now; thanks for updating us. I would say that it makes sense that you are doing better with the A2. The incorrectly structured casein protein in A1 milk is the cause of most dairy allergies (immune response.) As far as dairy intolerance (digestive issue,) I know that a lot of people think they are intolerant to lactose (sugar molecule) when it is actually the casein (protein molecule) that their body struggles to correctly break down. This is discovered when they switch to A2 milk and are relieved of symptoms that they previously blamed on lactose. However, lactose intolerance is still very real for many and I don't know that any study has really ever put the two issues side by side to see which is more common. Where exactly do you live? I am in the US and travel for work. I have found a couple brands of non-homogenized A2 milk in different areas. They are a mix of raw vs pasteurized, but are still non-homogenized. RAW FARM brand dairy. They are raw and non-homogenized. They also are 'grass grazed' so while not 100% grass fed, that is still decent. I have found them mostly in Sprout's Markets but are often in small health food stores as well. https://rawfarmusa.com/find Alexandre brand dairy. This brand has several options, all of which are A2 cream-top. So they aren't raw, but they are non-homogenized. They have varying fat options (2%, 4%, 6%) as well as a 100% grass-fed option. I usually see these in Whole Foods, but they're branching out to more national stores as well as small health food stores. https://alexandrefamilyfarm.com/pages/store-locator You can also use this national search engine that will show farms across the country. Its not updated very well, so call before you start a trip out somewhere because some of the farms close down or change offerings without the site knowing. https://www.realmilk.com/raw-milk-finder/

Elderberry extract increases testosterone and steroidogenic enzymes strongly. It lowers aromatase and 5areductase, which is unfortunate. To me it doesn't feel like it lowers DHT at all. Quite the opposite. So I'm wondering if the increase in androgen receptors and steroidogenic enzymes is enough to compensate . And, 5aR isn't the only pathway towards DHT, and the backdoor pathway wasn't tested so maybe it has to do with that . https://pubmed.ncbi.nlm.nih.gov/39683564/

Also by the same group: Identifying obesity and dementia risk: body adiposity and neural connectivity in cognitively normal, mid-life adults (2025) Obesity is a risk factor for dementia, creating a chronic inflammatory state that results in white matter (WM) injury. Edge density imaging (EDI) is a novel technique that has demonstrated reliability in quantifying WM changes. Thirty obese and 20 non-obese cognitively normal adults underwent structural and diffusion-weighted magnetic resonance imaging. Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were quantified via VOXel Analysis Suite by separating signal intensities of adipose and non-adipose tissue. Scans were processed by a pipeline (MaPPeRTrac) to generate EDI. Among obese participants, there was a negative association between the VAT/SAT ratio and EDI, which was not seen among non-obese participants. Additionally, males had decreased EDI compared to females. The results of this study suggest that obesity, through WM damage, may confer increased risk of dementia, with sex as a potential differential factor. EDI demonstrates promise in delineating the neuropathology of obesity and dementia.

@sunsunsun said in opinion on whey protein?: I took whey protein (dissolved in milk on peaty cereal) The estimated glycemic load (GL) of a meal containing 20g of whey protein, 240ml of half-skimmed milk, and 45g of buckwheat cereal is approximately 17 (medium GL classification). Between 10 - 20, the load is considered medium. Try first with some fibbers, mixed with coco oil. Coco must be above 30° C to get soft, easy to mix. No rice / almond "milk". Well hazelnut of cow milk. No cornflake, rather usual oat (no bran). NB: cereal or pseudo-cereal shouldn't be considered as a healthy meal. OK if you like it, 2x/wk. Listen to your feeling and adapt. When I eat oat ones (simply crunchy cereal, from Jordan, with honey), in hazelnut milk, I add some cut fruits. half an apple, or blueberries, e.g.

While I never experienced TMJ, I did go through a phase of teeth grinding. Mine was a result of caloric deficiency leading to hypothyroid symptoms. I was experimenting with fasting, and when I was eating I had a diet that didn't contain nearly as many calories as I thought it did. As someone with a fast metabolism, it was a recipe for disaster. Fortunately for me, its how I found Peat's work. Some of my other symptoms (the feeling of high stress hormones) lead me to the possibility that I was experiencing hypothyroidism. I did the Achilles tendon reflex test, and eventually came upon Ray. I started tracking calories with cronometer, and increased my intake of starches in particular. It was tough at first, but I forced myself to eat more, specifically carb dense foods like rice and concentrated fruit juice. Fasting had kind of destroyed my ability to "feel" hunger so it wasn't fun eating at times. I don't even know when the grinding stopped, but at some point I realized that when I forgot to put in my mouth guard before bed, I wasn't waking up with the edges of my teeth feeling rough anymore. Now and again if something happens and I don't eat enough, I won't feel hungry but I notice the stress horomones stirring up. If I don't correct it before bed, some grinding comes back. If I'm well fed, though, no issues ever.

just got some gaba powder. have some dmso too.... hmmmm... transdermal gaba applied to scalp to cross into brain.... hmmmm ... interdasdting.....

@Milchkanne Speaking as an American, I had one package confiscated by Customs back in 2020 or 2021. Probably because it had Ivermectin. They sent me a notice asking me for a bunch of paperwork. I didn't respond. Then they just went ahead and destroyed it. They said that because I'm an individual, not a company, I don't have to pay for the cost of the destruction. More recently I ordered medication from an Indian pharmacy. It was nothing controversial. This was just after the Trump administration said that they were putting all packages through customs. The de minimis rule was over. Drugs require prescription with the drug and all of that. Despite all that, I got it in about six weeks. It should have taken about two weeks, but it took six weeks. I did actually get it. I probably would consider ordering overseas again. I think they're probably just so backed up and busy they're just letting packages through anyway.

@yeyo12 My interpretation of the results were that caffeine co-administration with oxandrolone increased the absorption of the latter via inhibition of PGP.

@ThinPicking ok

@tocovit I was reading about stacking Mildronate & Pyrucet, trying to figure out how much is known about how they might synergize or conflict. I read the entire 31-page Pyrucet thread at RPF/LTF and only saw a few people discussing it. Does anyone have any theories, studies, experiences or thoughts about stacking these two? Is there any reason your dosing of these two is so moderate, given that you're going nuclear? Your "moderation in moderation" is a commendable philosophy I can endorse. I was hoping someone might have tried this stack and provide reports with doses like 500-1000mg Mildronate and 20-to-40 drops of Pyrucet per day, maybe divided by two BID. Interesting post. Keen to see any updates.

@LucH You get enough cysteine from protein foods. Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase https://pubmed.ncbi.nlm.nih.gov/20871132/ Glutathione (GSH) drives cancer metastasis by promoting cell survival under hypoxia https://haidut.me/?p=2816 https://doi.org/10.1158/2159-8290.CD-24-1556