@hawk1 okay you actually had agency & balls and settled with some pretty decent sources. It took you two months, but I’m proud of you if that means anything.

@dapose It varies, I don't take daily anymore as my body doesnt need it that much. Before I took powder so not exact dosages but approximately 300mg with a meal that doesnt have calcium and away from coffee. Genuinely life changing for me personally.

@Verdad update?

@alfredoolivas I should’ve specified, I was going to be using a very low dosage, I was prepared to lower my t levels a little bit just wanted to make sure it didn’t crash too much. Thank you for the help!

@sunsunsun Yeah, I personally haven't noticed a drop in strength though, despite losing 19lbs, but that is probably because I take tren. Though in all fairness, very little.

@CarbCarbCarbs said: I think it’s because of the higher amounts of copper. I don't think so. HD dark chocolate impact What are the negative impact of HD black chocolate: Side effects on cardia muscle and focus. Impact of High Level theobromine? Answer (Talk with AI - Google) The cardia muscle (the smooth muscle fibers surrounding the lower esophageal sphincter, or LES) and high-level (HL) theobromine changes the health dynamics entirely. [1] https%3A%2F%2Fwww.researchgate.net%2Fpublication%2F7901663_The_lower_esophageal_sphincter&ved=0CAEQ1fkOahcKEwiwj4HA9OqUAxUAAAAAHQAAAAAQKw&opi=89978449 When dark chocolate impairs your focus or causes a "wrong" energetic state, high levels of theobromine can trigger a cognitive crash and prolonged brain overstimulation. Concurrently, it causes a direct physical relaxation of the cardia muscle, promoting severe gastrointestinal reflux. [1, 2, 3] Cardia Muscle Dysregulation The cardia is the muscular anatomical zone where the esophagus meets the stomach. Dark chocolate negatively impacts it through two distinct mechanisms: [1]  Sphincter Relaxation: High-dose cocoa stimulates the release of nitric oxide and triggers a direct relaxation response in the smooth cardia muscle fibers. [1]  Acid Backflow: Once this muscular gateway loses its tone, the lower esophageal sphincter cannot close properly. This permits highly acidic stomach contents to escape upward into the esophagus, causing chemical irritation, chronic heartburn, and acid reflux. [1, 2] High-Level (HL) Theobromine: The Cognitive & Energy Disruption Theobromine acts primarily by blocking adenosine receptors (the chemical that signals sleepiness to your brain). While it is structurally similar to caffeine, its half-life is exceptionally long (7 to 12 hours). If your focus or energetic baseline is already misaligned (e.g., you are experiencing fatigue, ADHD-like executive dysfunction, or over-exhaustion), high levels of theobromine can exacerbate these issues: [1, 2, 3, 4, 5] PS: Never give a piece of chocolate to a cat, nor to a small dog because it may kill them. Toxic. They haven’t got the right enzyme to get rid of residual molecules. Explanation Chocolate contains methylxanthines—specifically theobromine and caffeine. While human enzymes break these compounds down +/ easily, cats and dogs (especially smaller breeds) metabolize them much slower, allowing toxins to build up in their systems. [1, 2]

@AlphaZance said: Metabolic stress drives the formation of AGEs, but Ray Peat has not addressed existing AGEs in foods. yes, but you didn't find the right doc. The etymology of the word glycation doesn't only rely on sugar. You d' better take care of "lipid glycation" and not only from sugar sources. Request for IA: glycation doesn't only rely on sugar but much more on fat alteration. Google answer: You are on the right track! While sugar drives classic glycation, fat alteration (lipoxidation) is a massive, often underappreciated driver of Advanced Glycation End-products (AGEs). The Lipid-AGE ConnectionLipoxidation: When fats oxidize, they create reactive, unstable molecules (like dicarbonyls). These intermediate compounds then cross-link with proteins just as sugar molecules do, directly forming harmful AGEs.The Maillard Reaction: Heat processing (such as frying or grilling) animal foods high in both fat and protein yields the highest levels of dietary AGEs. The Interplay: Both pathways are deeply connected under "carbonyl stress". How to Manage Both Sugar and Fat Risks To minimize the buildup of AGEs and slow down cellular aging, you can focus on a few evidence-backed lifestyle and dietary strategies: Watch Your Cooking Methods: Avoid cooking foods—especially meats and fats—at high temperatures. Steaming, boiling, or poaching creates significantly fewer AGEs than frying, broiling, or grilling. Balance Dietary Fats: The type of fat you eat matters. Clinical trials suggest that increasing consumption of monounsaturated fats (MUFAs) and Omega-3 fatty acids can help control and beneficially affect your glycation markers. Maintain Stable Blood Sugar: Even though fat oxidation is crucial, reducing refined sugar and fructose intake lowers the available "fuel" for traditional sugar-protein glycation.Leverage Antioxidants: Oxidative stress is the catalyst for fat alteration. Consuming antioxidant-rich foods or using targeted anti-glycation interventions helps neutralize free radicals. Scientific Sources & Evidence To dive deeper into the science of how fats and sugars alter your cells and skin, review these authoritative resources: [1, 2] https://www.lifeextension.com/wellness/aging/glycation https://www.skinnutritioninstitute.com/blog/glycation-how-fat-ages-your-skin-and-destroys-collagen-clone Glycation & Oxidation: Explore the exact breakdown of how lipid damage forms AGEs through Advanced Glycation End-products (AGEs): an emerging ... - PMC. [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC4648888/&ved=2ahUKEwjPyLaG4-iUAxXlkP0HHRf_BQEQy_kOegoIAggACAEIJxAC&opi=89978449&cd&psig=AOvVaw2nBJNpgaZPrk0yj1bOffN0&ust=1780497191863000 Lipoxidation Pathways: Read about how both carbohydrates and lipids drive carbonyl stress at Glycation, oxidation, and lipoxidation in the development of ... Ibidem Cellular & Skin Impact: Understand how these molecular processes affect your skin's health and elasticity in Sugar is altering your skin in ways no anti-ageing serum can ... Ibidem

This guy is a born liar and a fraud. His 'expert' research is incredibly sloppy and cherry picked. He has a raging ego, extremely thin skin and a tedious need to be the singular guru on ALL life matters. I challenged him on his claims on his blog about how much vitamin C he takes. He claims he only uses natural, acerola-based vitamin C, and claims he typically takes 4 grams a day for a few days and then settles on 2-3 grams a day. I found the brand he takes, crunched the numbers and worked out that if he was telling the truth, he'd be spending up to $400 a MONTH on this one supplement. I pointed this out to him and he wrote back calling me a "dumbass" and saying "of course I don't spend that much money on Vitamin C". Which means he out-and-out lied. He's also now making vague claims in his updated book that he had leukemia in the past. Previously he only mentioned the thyroid cancer. But now, leukemia too, because his WBC was slightly off. He is desperate to convince people he was at death's door and single-handedly fixed his multiple life threatening diseases. He's a dishonest loser, who loves to throw in comments implying he's hot af. He isn't. He's vain, preachy and profoundly wide of Ray Peat's mark.

Had to quit, after each smoke, my digestion got horribly worse… I came across this, and it makes sense: https://youtu.be/zZCgpw6_sRA?si=qcNsO9j7S8P_Aj-r Presently, I believe it’s the classic case of everything is bad when your health is outta wack. May try again when I think I’m doing good on every front.

@gg12 99% of people dont tolerate it. They simply never connect the dots of them being retarded feeling tired and gassey to the food they eat. Drink lac free low fat for a bit add glucose and then normal sugar to it

@ZackVegas https://www.meforum.org/middle-east-quarterly/why-arabs-lose-wars

Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage Results: Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. MAO-B activity positively correlated with ROS (r = 0.916, p < 0.001) and negatively correlated with SOD (r = −0.685, p < 0.001), whereas ROS negatively correlated with SOD (r = −0.661, p < 0.001) in co-DR1/2I-treated mice. The medium- and high-dose groups exhibited spatial memory impairment (longer escape latency, p < 0.05) in the water maze and more anxiety-like behavior (reduced central zone time, p < 0.01) in the open field test; however, no abnormalities in motor coordination were observed in the rotarod test (p > 0.05). Immunofluorescence and WB confirmed a reduction in the dopaminergic neuron count after co-DR1/2I.

@bio3nergetic said:What one most likely witnesses is big med making matters worse, but walking away silently pointing at made-up villains. >> Sounds like Finasteride and Dutasteride

@gg12 even if people are eating a lot they can be nutrient deficient.

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@Gaston Thirty ought six, carrot salad. [image: 1780011639454-55a687d1-f7bc-44b9-898d-1df8e6be50e1.jpeg]

@engineer Fair, lol about the creatine

@engineer I took some androsterone a while back but like 1-2 drops every few days. I took pansterone daily for 1 month as well.

Bananas have high Malic, zero citric acid