@lobotomize-me it's in the name of science ..it's ok .

I have ordered a device already.
And I'll probably first try over liver or gut.
Maybe later thyroid or testicles.

@DavidPS thanks for sharing.
This women has spectacular results by doing applying it her head.

https://x.com/MelRoBuilds/status/1901628623783682465

@serotoninskeptic yeah the ultrasound helps with bine growth AND vitamin K absorption so should be a good combo for fractures and so on .

At home devices are available in the price range of 50-200$/€

Peat rarely talked about ultrasound, but I suspect it can help metabolism by increasing local tissue heat and thereby mimicking a healthy metabolism for a while. There are also heat-independant effects, possibly through structuring the cellular water a la Gilbert Ling.

We're going dark Peat right away. But bear with me.

1.Ultrasound on balls.

This is only in vitro. But very impressive.
Ultrasound Increases Testosterone production in leydig cells by up to 80% .
Doubled StAR, the rate limiting enzyme for steroid production .
https://pubmed.ncbi.nlm.nih.gov/36613865/

Here's a rodent study showing 20 min/day for 7 days increased testosterone by 62%
https://pubmed.ncbi.nlm.nih.gov/1823286/

Someone filed a patent for using ultrasound for testosterone enhancement in humans. Including protocols and safe dosages.
https://patents.google.com/patent/WO2022026607A1/en?oq=WO2022026607A1

2.Anti-septic

They induced sepsis in mice.
After 5 days all of the mice were dead.

In the sepsis + ultrasound group half of the mice were still alive after 5 days. Not only that, they seemed to recover from sepsis and were still alive after 40 days!

https://www.umbjournal.org/article/S0301-5629(23)00093-5/fulltext

3.Ultrasound increases topical absorptionof substances.

Aspirins absorption was enhanced by a factor of 300 ! Topical aspirin anyone ?

Ultrasound also enhanced steroid absorption. I'm thinking Idealabs + ultrasound.

This might be useful for topical hair loss formulas like as well, since absorption can be an issue here.
https://pubmed.ncbi.nlm.nih.gov/8692734/

4.Other:

Ultrasound helps with Inflammatory bowel disease.
https://www.researchgate.net/publication/348880743_Non-invasive_peripheral_focused_ultrasound_neuromodulation_of_the_celiac_plexus_ameliorates_symptoms_in_a_rat_model_of_inflammatory_bowel_disease

Helps with osteoarthritis.

"Long-duration low-intensity ultrasound significantly reduced pain and improved joint function in patients with moderate to severe osteoarthritis knee pain."
https://pubmed.ncbi.nlm.nih.gov/30326947/

"Scientific evidence supports the use of LITUS to treat soft tissue injuries, and improve outcomes for musculoskeletal injuries and post-operative recovery."
https://pubmed.ncbi.nlm.nih.gov/30198009/

@wester130 https://bioenergetic.forum/post/38971

Interestingly 2,6DHBA is a fecal metabolite in humans strongly influenced by diet .

Apparently different benzoic acids are contained in fruits and other foods. And they alle seem to have anti-cancer properties . I suspect they undergo strong metabolism by the liver and the microbiome.

"Recent reports have demonstrated that the aspirin metabolites 2,3-dihydroxybenzoic acid (2,3-DHBA), 2,5-dihydroxybenzoic acid (2,5-DHBA) and the flavonoid metabolites 2,4,6-trihydroxybenzoic acid (2,4,6-THBA), 3,4-dihydroxybenzoic acid (3,4-DHBA) and 3,4,5-trihydroxybenzoic acid (3,4,5-THBA) were effective in inhibiting cancer cell growth in vitro. Limited in vivo studies also provide evidence that some of these hydroxybenzoic acids (HBAs) inhibit tumor growth in animal models."

" Interestingly, these HBAs are also abundantly present in fruits and vegetables. "
https://www.mdpi.com/1420-3049/25/9/2243

I have asked grok for the production process and then t does seem pretty strength forward, not involving too many steps.

Also the impurities are most likely derivatives .
From what I've read the bulk of impurities would consist of resorcinol, which can have anti thyroid effects but at dosages at least a 100 times higher than what we would ingest.
https://pubmed.ncbi.nlm.nih.gov/36693459/

It's 25g for like 130€ which is a pretty steep price so of someone in Europe wants to share it, let me know . The company below does indeed seem to ship to private users.

https://www.laboratoriumdiscounter.nl/de/26-dihydroxybenzoic-acid-980gct-25g.html

Grok Conversation:

"Producing 2,6-dihydroxybenzoic acid (also known as gamma-resorcylic acid) in a laboratory typically involves organic synthesis methods, often starting from readily available precursors. Here’s a general outline of how a lab might synthesize it, followed by an explanation of what the remaining 2% in a 98% pure sample might consist of.

Synthesis of 2,6-Dihydroxybenzoic Acid

A common approach to synthesize 2,6-dihydroxybenzoic acid could involve the following steps:

1. Starting Material: A typical starting point might be resorcinol (1,3-dihydroxybenzene), which already has two hydroxyl groups on the benzene ring. The challenge is introducing the carboxylic acid group at the 2-position.

2. Carboxylation: One established method is the Kolbe-Schmitt reaction, a carboxylation process:

   • Resorcinol is reacted with carbon dioxide (CO₂) under high pressure and temperature in the presence of a strong base (e.g., sodium hydroxide or potassium hydroxide).
   • The reaction proceeds via the formation of a phenolate ion, which attacks CO₂, leading to carboxylation. For 2,6-dihydroxybenzoic acid, the reaction conditions (e.g., temperature, base strength) must favor substitution at the 2-position ortho to one of the hydroxyl groups.
   • After acidification (e.g., with HCl), the free acid form of 2,6-dihydroxybenzoic acid is obtained.

3. Purification: The crude product is purified via recrystallization (e.g., from water or an ethanol-water mixture) or column chromatography to remove byproducts and unreacted starting materials, aiming for high purity (like the 98% mentioned).

Alternative routes might include:

• Oxidation of a precursor like 2,6-dihydroxybenzaldehyde or 2,6-dihydroxytoluene, though these are less common and require additional steps to prepare the starting material.
• Enzymatic or microbial synthesis in specialized labs, though this is more research-oriented than standard.

What’s in the Other 2% of a 98% Pure Sample?

If a lab offers 2,6-dihydroxybenzoic acid at 98% purity, the remaining 2% likely consists of impurities from the synthesis process. These could include:

1. Unreacted Starting Materials:

   • Resorcinol (1,3-dihydroxybenzene) if not fully converted.

2. Isomeric Byproducts:

   • The Kolbe-Schmitt reaction can produce positional isomers, such as 2,4-dihydroxybenzoic acid, if carboxylation occurs at a different position. The exact isomer distribution depends on reaction conditions.

3. Over-carboxylated Products:

   • Trace amounts of dicarboxylic acids (e.g., 2,6-dihydroxyisophthalic acid) if excess CO₂ reacts with the ring.

4. Degradation Products:

   • Phenolic compounds or quinones formed from oxidation or thermal decomposition of resorcinol or the product under reaction conditions.

5. Solvents or Salts:

   • Residual solvents (e.g., water, ethanol) from recrystallization or inorganic salts (e.g., NaCl, KCl) from the acidification step, though these are typically minimized in a well-purified sample.

6. Trace Contaminants:

   • Minor impurities from starting materials or equipment, such as metal ions or organic residues.

Quantification of Purity

The 98% purity claim is typically based on analytical techniques like HPLC (High-Performance Liquid Chromatography), NMR (Nuclear Magnetic Resonance), or titration. The certificate of analysis from the supplier might specify the major impurities if they’re significant. For most applications (e.g., research or industrial use), 98% is considered high purity, and the 2% impurities are usually negligible unless ultra-high purity is required (e.g., for pharmaceutical standards).

If you need a more specific synthesis route or impurity profile (e.g., for a particular supplier’s product), let me know, and I can refine the answer further!"

@wester130 peppermint = bad