Dandruff or scalp irritation? Try BLOO.
@tubert said in Olive leaf extract increases T3 + T4, lowers TSH:
@Mauritio how many mg a day are we talking about here to have those androgenic effects?
That was a high dose. 3-6g HED of the leave extract. It was in diabetic rats so its hard to convert to humans, probably best just to try it out.
Anti viral effects of olive leaf extract:
https://pubmed.ncbi.nlm.nih.gov/34839747/
https://pubmed.ncbi.nlm.nih.gov/38662719/
https://pubmed.ncbi.nlm.nih.gov/33541815/
https://pubmed.ncbi.nlm.nih.gov/15869811/
https://pubmed.ncbi.nlm.nih.gov/35496299/
@cs3000 Interesting. Peat right again I guess.
Unfortunately the other high dose study is circulating on X and people use it as an excuse to drink several cocktails a day and feel " fine".
Las time I took it it gave me bile flow issues , subjectively it was something which felt like choelstasis.
@Mauritio said in Random, interesting studies:
3,8-Dihydrodiligustilide
Strong phytoprogestogen.
https://en.m.wikipedia.org/wiki/3,8-DihydrodiligustilideIt has almost the same potency as progesterone (80% of it). And it has no estrogenic or anti-androgenic effects.
"EtOH extracts of the dried rhizome of L. chuanxiong demonstrated strongest
progestogenic activity, reaching 80% of that observed with progesterone (100 nM) and had an EC50 of 8 lg/ml (Fig. 1b). The bioactivity of L. chuanxiong extract was spe-
cific to the PR, and the extract was at least 200-fold less active on other related members of the steroid receptor family like androgen, estrogen and glucocorticoid receptors."
The plant Ligusticum sinense chuanxiong from which it is extracted is traditionally used to treat uterus issues. It also has been studied to treat strokes and Parkinson's.
In this review they look at the anti inflammatory effect of it.
Dates, olives and walnuts contain the highest amounts of the phytoprogestogen syringic acid.
Bloodroot seems to be by far the most potent progestogen they tested. It contains more than 10 times the amount of progestogenic parts than the next most active and it has no estrogenic activity, at least it does not promote cancer growth of estrogenic cancers .
https://journals.sagepub.com/doi/abs/10.3181/00379727-217-44247
3,8-Dihydrodiligustilide
Strong phytoprogestogen.
https://en.m.wikipedia.org/wiki/3,8-Dihydrodiligustilide
It has almost the same potency as progesterone (80% of it). And it has no estrogenic or anti-androgenic effects.
"EtOH extracts of the dried rhizome of L. chuanxiong demonstrated strongest
progestogenic activity, reaching 80% of that observed with progesterone (100 nM) and had an EC50 of 8 lg/ml (Fig. 1b). The bioactivity of L. chuanxiong extract was spe-
cific to the PR, and the extract was at least 200-fold less active on other related members of the steroid receptor family like androgen, estrogen and glucocorticoid receptors."
@TemetNosce how did you even get that stuff ?
@cs3000 yes me too.
I saw that too. Interesting.
Anecdotally i can say even small amount of alcohol seems to be very helpful when I have an incoming cold.
@cs3000 I saw one study with seven point five percent of ethanol, that did have negative outcomes.
So back to one tsp a day it is. I think a higher amount might be beneficial if it was spread out over the day as in the mice/ rats studies. That way you might get the continous antioxidant benefits. Maybe a few tsp's in your water bottle and then sip throughout the day.