@ThinPicking I don’t drink any water. I do drink a lot of fluids though (juice, milk, coffee, Mexican cokes) which require me to carefully balance my electrolytes with, so I’m constantly focused on mag, potassium, calcium, and sodium. Is there something I might be missing?

@jamezb46 I’m a male. When I started incorporating PROG, I was rotating PREG in and out. I think weening off PROG will require PREG, I just don’t know if it’s going to work as well. I’ve taken PREG for years and I love it but it hasn’t been so profoundly anti stress as progesterone has, I think it’s the missing piece for me, I just need to use it safely and responsibly. I’ll look into the other compounds, thank you.

8 days ago, I badly injured myself doing sprints. I pulled muscles, aggravated my lower L5 disk injury, flared up sciatica, etc. A few days later, I corrected a thyroid dosing problem (too low T4) which immediately improved but did not cure the injuries, especially the sciatica.

Before this debacle, I started experimenting with higher dose progesterone to improve my responsiveness to thyroid, to positive effects.

It’s taken a week for me to be in any position for > 30 seconds outside of just laying on my stomach. I can still barely move or walk. To quell symptoms, reduce pain, and relax my aggravated muscles and body, Ive been using progesterone in the 50-100mg range therapeutically, but then I found this.

“When you take progesterone steadily, without interruption, your liver interprets the constant high level of progesterone as being excessive, anything your liver experiences at high level, it produces enzymes to excrete. And so after 2 weeks, your liver has built up excretory enzymes that inactivate the progesterone. And so after 2 weeks, the effect of a given dose of progesterone is weaker. And stopping for at least a week lets your liver reset its threshold.”

My immediate reaction was to cease using the progesterone, where I tried and rapidly failed.
In 3 days, I will be 4 weeks into taking supraphysiological amounts of progesterone. That’s double the time Ray explained that the liver starts buffering against it.
My problem is I can’t come off of it, even for just a few hours. I take it immediately upon rising to stop the pain, and I need it regularly just to keep my symptoms at bay. I feel like I’m in a catch-22 - I possibly could not get better until I come off of and restore my body’s progesterone situation, but my body needs it and I can’t come off of the supplement because of how bad I feel when I try. I noticed that my reckless use of PROG has interfered with sleep, I don’t sleep nearly as much now and it’s interrupted. I know that can’t be good. I at least have the proper thyroid dose going for me, I’m praying that will solve all of this and I won’t need to use the PROG anymore. But what should I do? It seems like my body needs the PROG, I wonder if I should just keep taking it until my injuries clear up.

I recently discovered the root cause of my health problems and it’s related to endotoxin.

Research on my condition has indicated that there’s a chronic activation of TLR4, the toll like receptor that gets turned on by LPS, or endotoxins.

This activation causes my chronic IBS symptoms, makes it so my thyroid therapy can never work fully, and basically serves as a bottleneck to my health that can’t change until I rectify this.

I’m already doing everything I can to minimize endotoxin itself, but I want to focus on the TLR4 receptor too and see if I can antagonize that as well, it seems to be very important.

Does anyone know of any ways to impede or antagonize this receptor?hopefully quelling some symptoms?

Follow-up/ update: I’ve looked into this a little more.

BDDE is the cross linking agent that they use to make the filler more durable. I’m going to look into taking care of that.

Beyond that, some people have set that the filler creates fibrotic tissue, and anti-fibrotic agents are being used by doctors to treat fillers. So that’s definitely a potential method for treatment, and I’m currently looking at Dissolve-It-All, DeFibron, and Ray’s healing marmalade.

I also think (just from my own experience and observations) that calcification is involved. Mainly because I’ve been seeing the are and my overall face shape improve after regularly taking more vitamin K.

Last, water retention seems to be a key element to this. I believe hyaluronic acid affects water regulation and causes some edema and swelling. I think that is a mechanism that the filler uses to “plump up”. Estrogen (opposing it) and potassium (supplying sufficient amounts) are going to be focuses here, with more future considerations.

That’s all for now. Trying to learn and get help as much as I can

@zorba990

Thank you so much for the recommendation. I contacted her.

I wanna talk about filler.

About 6 years ago, I got under eye filler to help my appearance. I’ve hard serious dark circles forever, and after reading online, I gathered that it was genetic and that there was nothing I could do to fix it - besides under eye filler.

I now know, this couldn’t be further from the truth. I was so misguided at the time, very unhealthy and unhappy, this was before I ever found Peat.

Anyway, I got the procedure done pretty easily. They used Juvederm, which is a hyaluronic acid-based filler. I was told it was the most mild option and that it would fully dissolve on its own as our bodies break it down. This already exists in our bodies - how bad could it be?

Right after injecting me, I got a rapid heart rate and overheating/fever situation, and I almost passed out. I thought nothing of it at the time, but that should’ve been my first clue that this situation was not great.

Anyway, many years later, I’ve lost and regained health. Now that I’ve been losing weight, and my figure is becoming tighter and back to what it was growing up, my face has been slimming out too. I’ve been trying to figure out why I have these chubby cheeks, and I kept telling myself I just was overweight and that part of the weight hasn’t come off yet.

But I’m pretty sure now that’s not true. I have this weird, uncanny valley look to my cheeks (I think the filler sunk down a little from my under eyes) and it looks puffy and especially misshapen/lumpy when I smile, kind of ruining it. This looks extra strange on someone who’s always had extremely sharp / defined features.

Luckily for me, I don’t look like Zac efron or Matt Gaetz, as I only had .25-.5 of a filler tube in my face. But it’s still enough to bother me and want my good looks back.

I’ve been looking into this as much as I can. Theres a lot of gaslighting with this cosmetics stuff but take it from me, IT DOES NOT DISSOLVE! It’s been 6 years for me and most information said online it was to be gone in 2.

I really just want this shit out of my face, so I started researching what I do. Turns out the whole plastic surgery/ filler industry have started dissolving fillers with something called hyaluronidase, with concerns over it dissolving our own tissue too. There’s even a Facebook group with horror stories. But it seems some have had good experiences with reducing the lumpy puffiness left over from fillers. I haven’t yet decided if it’s another scheme to make this beauty industry cyclical, or if it honestly just gets rid of the old filler, as some have said and have actually shown.

After going through this and now setting out on trying to fix it, I don’t think the risk outweighs the reward. I got the smallest amount of the safest filler, and I’m trying to overcome that mistake 6 years later.

If there was a natural or supplemental method to help dissolve or metabolize this stuff, I’d love to know about it and look into it. I want my beautiful defined bone structure back, is there a safe way to do that?

@sneedful I haven’t yet but I’ve been thinking about it. Have you?

Hello, I was wondering if anyone here has any experience with Vitamin C supplementation?

Vitamin C is a potent agonist of diamine oxidase, which plays a critical role in the elimination of histamine.

In the past, I’ve tried Quali-C, and I know it’s supposed to be better than typical ascorbic acid supplements, but I did notice it didn’t agree with me very well, so I’m looking to go a different route.

Has anyone tried Vitamin C from acerola or camu-camu? I’m a bit more cautious against rosehips since I’m very digestively sensitive.

What dosages did you take? What brand did you use? I have Matt Blackburn’s “Whole C” but I’m looking for something a little less trendy and a bit more reliable / clean.

Thank you for any and all input!