Rose thorn disease! Oral itraconazole or terbinafine?
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Sporotrichosis, commonly known as "rose gardener's disease," is a skin infection caused by the fungus Sporothrix schenckii, which is often found on rose thorns and other plant materials.
Starts as a small painless red, purple, or pink bump on the skin. Over time, more bumps may start to appear and grow larger. Eventually they may start to pus, become open sores, and spread up the arm or from the infection site.
The treatment is several months of oral antifungal medication, like itraconazole or terbinafine or medications like supersaturated potassium iodide (SSKI).
I don’t want to take the antifungals. I am painting the area with white iodine and layering one drop of dmso. Hoping to stop the enlarging lump under the skin and the spread.
Anyone have other ideas? itraconazole is associated with heart failure!
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stacking fluconazole with doxycycline makes it more effective for treating some candida species due to the iron chelation ability of doxy so maybe if you use terbinafine you could also add doxycycline. Maybe that will make it nearly as effective as itraconazole. Also some red light on the affected area will probably be good, and I would use some topical antifungals as well even though the info says topicals dont really do much for sporotrichosis.
Apparently heat is a valid treatment method too.
Fluconazole itself has worked in some cases btw, the one I'm reading says a once weekly dose of 200mg worked, over months. I've also seen how terbinafine can be used for other types of infections in animals with not-everyday dosing. So you have some options. Basically you just need to beat back the fungus enough that your own body can clear it and that doesn't necessitate daily dosing.
There's a case study of a cat with sporotrichosis treated with methylene blue and light, and "low" doses of itraconazole.
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@Bingo here's a good case report on MB and daylight
They injected MB 1% into the lesions and then had him go in sunlight for 2 hours.
