Essential Fatty Acids (Omega-3 & Omega-6) are direct building blocks for the skin's lipid bilayers, reducing transepidermal water loss (TEWL).
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Transepidermal water loss (TEWL), dehydration, and metabolic acidosis are clinically connected, most commonly in the context of severe burn injuries or major skin barrier damage. A breakdown of the skin causes water to passively evaporate, which reduces blood volume, lowers tissue perfusion, and leads to acidic blood.
Changes in Transepidermal Water Loss and Skin Hydration according to Expression of Aquaporin-3 in Psoriasis
https://pubmed.ncbi.nlm.nih.gov/22577267/The repair of impaired epidermal barrier function in rats by the cutaneous application of linoleic acid
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2133.1976.tb04336.xAnti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils
https://doi.org/10.3390/ijms19010070Changes in transepidermal water loss and the composition of epidermal lecithin after applications of pure fatty acid triglycerides to the skin of essential fatty acid-deficient rats.
https://doi.org/10.1111/j.1365-2133.1976.tb07012.xKrill oil supplementation improves transepidermal water loss, hydration and elasticity of the skin in healthy adults: Results from two randomized, double-blind, placebo-controlled, dose-finding pilot studies
https://pubmed.ncbi.nlm.nih.gov/39169540/Diet and skin barrier: The role of dietary interventions on skin barrier function.
https://doi.org/10.5826/dpc.1101a132The role of linoleic acid in skin and hair health: A review.
https://www.mdpi.com/1422-0067/26/1/246Feeding the Skin Barrier: The Impact of Macro‐ and Micronutrients on Skin Barrier Function
https://pmc.ncbi.nlm.nih.gov/articles/PMC12626168/Skin pH–dependent Staphylococcus aureus abundance as predictor for increasing atopic dermatitis severity
https://onlinelibrary.wiley.com/doi/full/10.1111/all.14461
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