This is very interesting, but a few things I don't grasp:

• While nowhere near as small as the methionine restricted tumor, the serine/glycine restricted tumor seems to be smaller than the 'complete' tumor. So, pushing glycine in addition to restricting methionine might not be the way to go? If the tumor growth is driven by methylation and glycine reduces methylation, then wouldn't the glycine restricted tumor grow even bigger?

• In the pictures the glutamine restrited tumor looks bigger than the serine/glycine restricted tumor. But the graphs say otherwise. (This might be due to the fact that we just see 2 dimensions of the tumors in the pictures and it therefore is not a good depiction of its volume.)

• They used the exact same 'complete' tumor for comparison in pictures 2 & 3 but another one in picture 1. Why is that?

(I assume the full study explains more about these things, but I can't open neither of the 2 links to the full text.)