Getting rid of gyno
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I experienced gynaecomastia when I was 19, I think in part as a response to starting to lift weights and eat more as well as probably some late pubertal development.
It was only on the left side, and was very sensitive. Doctor was of course very little help and decided to put me through a breast cancer screening, so I took matters into my own hands by getting my hands on some Tamoxifen (Nolvadex). I dosed it at 20mg ED for 2 weeks, it resolved itself by day 9 and never came back.
Tamoxifen has a slightly better reputation than clomid as far as SERMs are concerned, but I'm aware of the fact it's considered to be hepatotoxic amongst other side effects. Either way, it's been years since and I've not had an issue of it's kind again, and I think the cost and time investment is low enough to consider it in cases of pubertal-associated gyno, especially when it's a recent development.
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@BigusDickus said in Getting rid of gyno:
Talk to doctors, patients, and people who've had gynecomastia for years. Look into the literature. It's NOT an easy solution and complete reduction is unheard of BECAUSE the tissue has become metabolically inert, for the most part.
I bet these people are hormonal wrecks that have been ignored by doctors though. Is there any research on using thyroid etc for gyno?
Dr. Ray Peat: Thyroid supplements can be useful for prostate hypertrophy and some cases of impotence and infertility. Occasionally, a man who can’t put on a normal amount of weight finds that a thyroid supplement allows normal weight gain. Leg cramps, insomnia and depression are often the result of hypothyroidism. Heart failure, gynecomastia, liver disease, baldness and dozens of other problems can result from hypothyroidism.
The activity of aromatase increases with aging, and under the influence of prolactin, cortisol, prostaglandin, and the pituitary hormones, FSH (follicle stimulating hormone) and growth hormone. It is inhibited by progesterone, thyroid, aspirin, and high altitude. Aromatase can produce estrogen in fat cells, fibroblasts, smooth muscle cells, breast and uterine tissue, pancreas, liver, brain, bone, skin, etc. Its action in breast cancer, endometriosis, uterine cancer, lupus, gynecomastia, and many other diseases is especially important. Aromatase in mammary tissue appears to increase estrogen receptors and cause breast neoplasia, independently of ovarian estrogen (Tekmal, et al., 1999)
Gynecomastia (and galactorrhea) associated to the use of conventional and certain atypical antipsychotics can be related to high prolactin levels.
https://pubmed.ncbi.nlm.nih.gov/34933535/ -
Low-fat milk + raising your metabolic rate could help with gyno.
A non-peaty way of getting rid of gyno would probably to do cardio everyday increasing the metabolic rate through stress hormones, albeit temporarily.
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@Cornelyan I don't think it's possible for Androsterone to convert to Estrogen. It's non-aromatizable.
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@GreekDemiGod You're right idk why I wrote that, to compensate for my idiocy I'll add that androsterone creates a good synergy against aromatizable compounds such as DHEA, as haidut told about an efficient ratio of 1:3 in the favor of DHEA combined with andro inhibiting aromatase in a significant manner
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@peatilian This is great. I have also some spare DHT powder so I will try this. In the past was trying this only with a Ethanol but DMSO could work better. Will try and report back.
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@Chud Sure it wasn't progestin?
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@Chud I would hazard to guess that they may be using cheaper progesterones, which have estrogenic metabolites which Ray said exacerbated estrogenic symptoms, or they’re taking too much, which will indeed aromatize, hence Ray advocating such small doses as 3.5mg.
If using progest-E, the E antagonizes estrogen, and don’t quote me, worth looking further, but I think it may block aromatization as well. -
@raccoonmilk said in Getting rid of gyno:
@enjoyeroflife if you live in California I am able to make the incision and remove the hard gland with leftover lidocaine that I have for a fee though, its the liposuction afterwards that I am unable to preform this would have to be after my mom gets off work to drive me because I am 18 with no license.
Sounds like you drink raccoon milk
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What would be better to try? The 11 keto dht or androsterone for topical application to reduce nipple puffiness. I’ve had it since my low carb days
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@peatilian said in Getting rid of gyno:
I ran topical DHT solved in DMSO for 5ish weeks starting at 25mg/day and titrating up to 50mg/day the last few weeks.
Topically applied evenly to each nipple and had a ~50% reduction in size of gyno which then tapered off towards the end.
Am now on first week of topical (wrist) androsterone at 16mg/day hoping to see similar effects.
You got any update on this? Also have you had bloods done? DHT didn't suppress you?
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Hello everyone,
It should be noted that renal deficiencies have a very strong correlation with gynecomastia.
I've had slight kidney dysfunction for all lf my life and started getting light gynecomastia at 18. Nothing alarming but it's there.Hence everything that improves kidney function might improve gynecomastia.