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How to lower myostatin?

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  • B
    Bran
    last edited by Feb 1, 2024, 6:33 AM

    I've been on a gym journey for a while now, and now I've been wanting to try to lower myostatin more and more to try to achieve a greater building of muscle in a shorter period of time. I have been looking into creatine. Apparently, creatine lowers myostatin and promotes satellite cells. I've also heard epicatechin (from cacao and other sources) is really good at lowering myostatin.

    Add on and advise!

    Neanderthalmaxxing

    1 Reply Last reply Reply Quote 0
    • C
      Cabron
      last edited by Feb 1, 2024, 4:15 PM

      I've been trying epicatechin, ecklonia cava and Sulforaphane to lower myostatin. That combined with a 5 day weight lifting routine seems to be having good results for me over the past 6 months.

      The epi and ecklonia I use twice a day while the sulfo I only use once combined with a meal.

      B 1 Reply Last reply Feb 2, 2024, 5:58 PM Reply Quote 0
      • B
        Bran @Cabron
        last edited by Feb 2, 2024, 5:58 PM

        @Cabron Very nice. I do know that working out with resistance training does lower myostatin levels. Though, I've heard that myostatin goes to baseline after around 8 hours?

        I have been thinking about working out on certain 'hard gaining' muscle groups, like calves, daily. Though, I have to do more research. I do not know if training decreases myostatin levels throughout the whole body, or just in the muscle groups that you are training.

        Neanderthalmaxxing

        C 1 Reply Last reply Feb 2, 2024, 9:43 PM Reply Quote 0
        • C
          Cabron @Bran
          last edited by Feb 2, 2024, 9:43 PM

          @Bran I have also read that it goes to baseline after 8 hours, I usually workout in the morning so I target to lower it again with my night doses and consume plenty of protein to give the body something to work with while I recover in my sleep.

          I'm not sure if working out certain groups would have a systemic effect on myostatin levels. I do a Pull Push Legs routine over the week, around 1 to 1.5hr daily.

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          • M
            monadology
            last edited by Feb 3, 2024, 1:07 AM

            YK-11 is a myostatin-inhibiting SARM. However myostatin is probably a poor lever to improve body composition and may be harmful to alter. Total myostatin inhibition would impact all muscles, including the heart, which is not good. Furthermore myostatin seems to be necessary for strong tendons. I would continue to exercise, sleep well, and take creatine, all of which are good for you, but I would not throw money at the issue of myostatin inhibition absent a genuine muscle wasting disorder (in which case get real medical advice).

            B 1 Reply Last reply Feb 3, 2024, 2:24 AM Reply Quote 0
            • B
              Bran @monadology
              last edited by Feb 3, 2024, 2:24 AM

              @monadology Yeah. I'm definitely not wanting to go all out, like with YK-11. I mainly strive for lowering myostatin to a reasonable level to squeeze a little extra gain out, lol.

              Neanderthalmaxxing

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