How to reverse suppressed appetite as a result of prolonged ADHD medication?
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Try Cyproheptadine, it is a well known appetite stimulant and is prescribed to promote weight gain in children and adults with poor appetite. Most people who've tried it here say that it definitely makes them more hungry. Here's a study showing it's effectiveness: https://pubmed.ncbi.nlm.nih.gov/34509304/
I would recommend you start with around 1mg before bed. it's going to make you very tired the first few days of taking it. -
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@Peater0921 You build up a tolerance to it, so I think you should take 1mg before bed for the first couple days until you stop feeling tired, then start taking 2mg a day and so on. I think for long term usage 2-4mg a day would be good, you could probably go up at 8mg a day and be fine but you just have to experiment. I also think after 8 weeks you should take a tolerance break for 1-2 weeks just so it doesn’t lose effectiveness.
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@Peater0921 I'm 125 lbs at 5 ft 10 and I have the same issue, I'm never hungry.
I tried cypro 14 days back in spring and it didn't have any noticable effect apart form making me tired throughout the day, I was taking 2mg every evening.
When I eat, things usually stay on my stomach for longer than I would assume is the average and the same I think is true in my intestines. Sometimes when I eat a big meal it stays on my stomach for 3h or 4h, and so I'm not hungry at all, I'm even repulsed by food.
I never have diarrhea, but very often constipation. I also have some kind of malabsorption because my stools are very often light in color and float, despite the constipation.I'm interested on how to increase appetite through improving gut motility and absorption as well, if some posters have insights.
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@Peater0921 said in How to reverse suppressed appetite as a result of prolonged ADHD medication?:
I believe years of taking ADHD medication as a child have permanently tanked my appetite signaling.
I used to be fat as a baby, but once I got a bit older and more "energetic," my parents started medicating me. It killed my hunger completely every time, so I would not be hungry the whole day, and whenever I did eat, it only took very small amounts to satiate me.
Now as an adult, I haven't been on the medication for many years. But even after stopping the medication, my appetite has been the same ever since: non-existent for most of the day, and when it does eventually show up, a few spoons are enough to make me feel completely full. Naturally, this kind of appetite has left me underweight, with 132 lbs for 6 ft 1.
Is there any way for me to reverse this?
Thiamine deficiency is known to cause anorexia
Thiamine supplementation reverses anorexia
Many pharmaceutical drugs block thiamine function. When my own thiamine function was blocked by taking Bactrim antibiotic, it remained blocked after stopping the Bactrim. High dose thiamine hcl restored my health.
If you have been deficient in thiamine for a long time, the body makes adjustments so you don't die, including down regulating various enzymes etc.
Thiamine, Epigenetics, and the Tale of the Traveling Enzymes
High dose thiamine can resolve the problem.
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Cannabis is a really good option for people struggling with appetite issues
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@Peater0921 My husband takes Thiamax (TTFD) and has done well on it. He started with 100mg, then increased it to 200mg after a few weeks. He never had a negative reaction to it and still takes it (100mg, 2Xday). It has improved his health!
I tried to take TTFD in 2020. However, I was unable to tolerate it because my glutathione level was low due to my high level of oxidative stress. TTFD uses glutathione to work (somehow, some way) so I reacted badly to it; one 100mg pill gave me a headache that lasted 36 hours. So I take thiamine hcl which does not use glutathione and has actually increased my glutathione level to normal.
Paradoxical Reactions With TTFD: The Glutathione Connection
Dr. Chandler Marrs has some good videos and does discuss various patients who take higher doses of TTFD. The amount needed varies a lot depending upon your body's situation.
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@Peater0921 said in How to reverse suppressed appetite as a result of prolonged ADHD medication?:
I will try it too then, thank you so much!
Good luck to you! I hope it works out for you. If you find you react negatively to the TTFD, there's always thiamine hcl. Dr. Costantini said that no negative effects should happen from taking thiamine hcl.
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@mostlylurking I've started trying Thiamine HCL 100mg/day a few days ago because of my high simple sugars intake, nothing out of the ordinary so far but no bad side effects either
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