ADHD, Severe fatigue, digestion problems etc..

Floradix.. some german brand with some herbs and berry juice and b vitamins. Not the best but better than having crappy filler. 15mg iron a day.

I do feel a bit better and maybe walking slightly more straight. Slow to tell yet.

@Razvan said in ADHD, Severe fatigue, digestion problems etc..:

@questforhealth
Taurine should help for the digestion and also help utilize iron and copper better.
Be carefull with too much B1, it's very good indeed, but can raise acetylcholine too much to the point of making your racing thoughts much worse. Keep in mind what you feel and be aware of your experience even tho it's crazy hard to focus when having low iron and/or low copper.

Actually, thiamine (B1) modulates acetycholine (I think) so the body is less likely to get overloaded with acetylcholine if your thiamine is adequate for your needs. The action of thiamine is extremely broad and complex. The following article is really above my pay grade; I'll slog through it another day, when I'm not as tired.

Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis
"Our interdisciplinary study shows that thiamin is not only a coenzyme for acetyl-CoA production, but also an allosteric regulator of acetyl-CoA metabolism including regulatory acetylation of proteins and acetylcholine biosynthesis. "

This seems awesome. If I keep taking iron and thiamine and my digestion kicks back in and I can start eating high quality meat and organs... Lots of good stuff can happen surely.

@questforhealth said in ADHD, Severe fatigue, digestion problems etc..:

@Razvan

Floradix.. some german brand with some herbs and berry juice and b vitamins. Not the best but better than having crappy filler. 15mg iron a day.

I do feel a bit better and maybe walking slightly more straight. Slow to tell yet.

I want to voice a word of caution about supplementing with iron. If you are deficient in thiamine, your blood brain barrier can become compromised and the iron can get through it and into your brain and damage it.

@mostlylurking

Aha! So stick to thiamine and magnesium for a start.

I know thiamine can chelate excess iron out of the brain though. so no worries

Razvan

@mostlylurking
The study clearly mentions thiamine also increasing acetylcholine synthesis, but of course thiamine is extremly helpfull and there is even some studies showing that in low dosages increases acetylcholine while in high dosages lowers it due to restoration of the receptor.
I was just making the OP aware of the symptoms.
Thiamine could help ATP and improve hypoxic tendencies when anemic with low oxygenation. Helped with that for me in a similar situation.

@Razvan

Do you feel good eating pork from healthy animals? I am considering trying for the thiamine..

Razvan

@questforhealth
Thiamine can chelate iron, but will not make you more anemic, it's not so strong in doing that as with aspirin and or vitamin E.

Razvan

@Razvan Btw, it's very hard, almost impossible to have high acetylcholine when being anemic and or iron deficient. You are just stuck in a adrenalized, sympathetic and most likely you lack normal vagus nerve function and parasympathetic function which should allow you to relax, that's where acetylcholine could help, most likely you will benefit from stuff like thiamine increasing or regulating acetylcholine.
I did.

@questforhealth said in ADHD, Severe fatigue, digestion problems etc..:

@mostlylurking

Aha! So stick to thiamine and magnesium for a start.

I know thiamine can chelate excess iron out of the brain though. so no worries

It would be a safer plan to just do the thiamine, magnesium glycinate, riboflavin, and niacinamide. I provided the doses that I take earlier. That said, Dr. Costantini preferred for his patients to stop all other supplements for a few weeks in the beginning of taking the high dose thiamine so that he could confirm to his satisfaction that the improvements he saw were indeed due to the thiamine. So I take this to mean that it really isn't necessary to slam yourself with all this stuff all together in the beginning. That said, I didn't stop taking my other supplements when I started taking high dose thiamine. You get to decide; it's your body. Just don't overwhelm yourself with a bunch of new stuff at once or you will have more difficulty discerning which one is doing what.

Razvan

@questforhealth
I don't eat pork, i don't see it as a good protein source.

@Razvan
Not even pork that is red like beef? From a good farm?

Razvan

@questforhealth Could be good, better, yes.
I don't have access to good farm pork.

Yeah I will have to see. I’ll need to tryout the thiamine. I’ve taken B3 and B2 before with good results too so I imagine they should all benefit me.

I guess since i’m so sick it’s going to take a while. If the digestion kicks back in that would be the best.

@questforhealth said in ADHD, Severe fatigue, digestion problems etc..:

@mostlylurking

Oh I’ve had weird serotonin stuff before.

If I eat the wrong thing I feel like i’m on an ssri. Serotonin overload.

A banana or a little pineapple used to cause me some serious serotonin overload symptoms. Now I can eat a banana again without that problem so I know my brain serotonin is much better.

I was unable to tolerate the tiniest dose of methylene blue during that same time.

@mostlylurking

Do you think metals from vaccines are what causes us to have these insane needs for B1??

@questforhealth said in ADHD, Severe fatigue, digestion problems etc..:

@Razvan
Not even pork that is red like beef? From a good farm?

I don't eat pork either. Pigs aren't ruminant animals so their fat is the same as what they're fed which is PUFA.

@mostlylurking

Yeah but you wouldn’t eat pigs fed milk and potatoes? Seems like a clean food but I’m not sure..

@questforhealth said in ADHD, Severe fatigue, digestion problems etc..:

@mostlylurking

Do you think metals from vaccines are what causes us to have these insane needs for B1??

They do contribute to the body's load of toxins, including heavy metals.

Here's a list of sources for mercury.

@mostlylurking

My long term plan is to test for heavy metals then chelate them out the body. But I know vitamins taken the right way can help my symptoms in the mean time at least. Really hope so as I’ve had great results in the past.