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Peaty migraine remedies?

Bioenergetics Discussion
migraine
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  • N
    normalgirl
    last edited by Jan 30, 2024, 1:10 AM

    I’m aware that Ray Peat suffered from migraines IIRC, but what could be considered a good treatment for them?

    ~normalgirl*+•.’

    S D 2 Replies Last reply Jan 30, 2024, 2:21 AM Reply Quote 0
    • H
      Hando-Jin
      last edited by Jan 30, 2024, 2:15 AM

      hey

      Someone close to me is a migraine-r. It usually begins with intestinal problems for her, which is a clue I think that it is starting with massive intestinal inflammation. A decent dose of minocycline (200mg) combined with 2mg of cyproheptadine usually knocks it out for her and spares her two days of agony.

      My mother also had migraines for years while she was going through menopause, so probably an estrogen thing there.

      I think migraines are always a metabolic problem, you just have to find out which pathway it's happening along. Ray said he got his under control just eating a carrot everyday.

      Progesterone, thyroid, lisuride, metergoline, cyproheptadine, carrots for for the fibre, cascara and anything strongly anti inflammatory like aspirin and minocycline are things you could experiment with.

      N 1 Reply Last reply Jan 30, 2024, 7:20 PM Reply Quote 0
      • S
        Smitty @normalgirl
        last edited by Jan 30, 2024, 2:21 AM

        @normalgirl Are they frequent? Most bioenergetic principles reduced the frequency of mine. Have you experimented eliminating certain food groups – gluten, sulfur, salicylates, etc.? 2 aspirin tablets and a nap obliterate my migraines.

        N 1 Reply Last reply Jan 30, 2024, 7:23 PM Reply Quote 0
        • D
          Dakota @normalgirl
          last edited by Jan 30, 2024, 2:22 AM

          @normalgirl I think peat has recommended both 100mg progesterone and vitamin B2 as remedies for migraines.

          L 1 Reply Last reply Jan 30, 2024, 2:37 AM Reply Quote 0
          • L
            latinxgoku @Dakota
            last edited by Jan 30, 2024, 2:37 AM

            @Dakota

            Riboflavin is effective for migraine prophylaxis as 400 mg/day significantly reduced migraine incidence and severity.

            https://pubmed.ncbi.nlm.nih.gov/33779525/

            D 1 Reply Last reply Jan 30, 2024, 2:53 AM Reply Quote 0
            • I
              izkrov
              last edited by Jan 30, 2024, 2:46 AM

              Cutting out pufas and taking progest-e stopped my migraines, haven't had one in 2 years.

              1 Reply Last reply Reply Quote 0
              • D
                Dakota @latinxgoku
                last edited by Jan 30, 2024, 2:53 AM

                @latinxgoku nice. The only issue is I think that might be way too high of a dose from a bioenergetic perspective.

                S L 2 Replies Last reply Jan 30, 2024, 3:05 AM Reply Quote 0
                • S
                  Smitty @Dakota
                  last edited by Jan 30, 2024, 3:05 AM

                  @Dakota @latinxgoku You're right, Ray said doses >10mg are allergenic.

                  1 Reply Last reply Reply Quote 0
                  • L
                    latinxgoku @Dakota
                    last edited by Jan 30, 2024, 3:05 AM

                    @Dakota

                    It probably is, the dose was given in consideration to see optimum pharmacokinetics of riboflavin for migraine patients.

                    1 Reply Last reply Reply Quote 0
                    • A
                      anabology
                      last edited by Jan 30, 2024, 3:11 AM

                      My migraines weren't fixed until I upped my sugar intake significantly and cut out all PUFAs. I started eating more eggs recently and headaches have started to creep back. Think I'm going to go back to my default diet.

                      See diet here:
                      https://longestlevers.com/anabology-top/good-foods.html
                      Use the upper menu w/ high sugar content and lower fat and it should work very well for migraines

                      A S 2 Replies Last reply Jan 30, 2024, 3:13 AM Reply Quote 0
                      • A
                        anabology @anabology
                        last edited by Jan 30, 2024, 3:13 AM

                        @anabology This is for prevention but treatment I throw everything at it if it happens:

                        • t3 -- higher dose than I usually tolerate
                        • 1g aspirin
                        • a lot of baking soda
                        • latte with a ton of maple syrup
                        • progesterone
                        • more calories
                        • sparkling water if thirsty
                        K H 2 Replies Last reply Jan 30, 2024, 4:01 AM Reply Quote 0
                        • S
                          Smitty @anabology
                          last edited by Jan 30, 2024, 3:26 AM

                          @anabology It's fascinating how bioindividual we all are. Due to a recent hypersensitivity to salicylates, potatoes are my primary carb source and I haven't had an increase in migraines.

                          1 Reply Last reply Reply Quote 0
                          • A
                            ah
                            last edited by Jan 30, 2024, 3:35 AM

                            Drinking lots of coca cola and taking niacinamide and b6, to start.

                            If its bad, I noticed that taking a little bit of metergoline (any ergoline dopamine agonist/serotonin antagonist should do) can make a migraine vanish instantly
                            Makes sense considering that migraines are largely serotonin driven, particularly at 5HT2 receptors. The most powerful anti-migraine drugs are all either direct 5HT2 receptor antagonists (particularly preventatives such as pizotifen, cyproheptadine, methysergide, etc) or indirectly via 5HT1 agonism, such as with triptans. Anyway, its well established even in mainstream medicine that serotonin drives migraines: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3451809/pdf/10194_2001_Article_8.pdf

                            I suspect ergolines are most effective, but like I mentioned, anything that antagonises serotonin should work, cypro, pizotifen, other antihistamines that antagonise serotonin, mayyybe famotidine if youre in a pinch, not sure about that one
                            Of course, any problem involving serotonin starts in the gut, where most serotonin is produced and serotonergicity driven by endotoxin. So a diet that absorbs in the stomach and upper third of the intestine is important. And the usual remedies, carrot salad, oregano oil, antibiotics if you absolutely need it.

                            N 1 Reply Last reply Jan 30, 2024, 7:35 PM Reply Quote 0
                            • K
                              Kruton
                              last edited by Jan 30, 2024, 3:59 AM

                              BAKING SODA!!

                              Seriously the biggest contributor to relieving my lifelong migraines was this, food grade baking soda. I always throw everything i have at it now. The concoction is baking soda, progesterone, ginkgo bilobo, salt, thyroid, creatine, aspirin, caffeine, and ice cream. I have completely remedied myself with this. They use to get so bad i could only huddle up in the middle of my bed with my eyes closed, couldn’t move, paralyzed in the pain. High doses of ibuprofen seemed to be the only relief and after taking it i’d fall asleep. Now i don’t have to take that detrimental ‘medicine’ to help my migraines.

                              Baking Soda and/or Salt
                              Progesterone
                              Aspirin
                              Creatine
                              Thyroid
                              Ginko Bilobo
                              Caffiene
                              Icecream

                              Sometimes kratom but not needed now if I have the above. Migraines cured.

                              ps- i have recently added cypro from idealabs to my stack and it is also supposed to help with migraines, i haven’t had another since but when/if i do i’ll try cypro for it to see how it fares. I gave my mother some after she developed one and it seemed to help along with magnesium glycinate as that is wat i had on hand.

                              1 Reply Last reply Reply Quote 0
                              • K
                                Kruton @anabology
                                last edited by Jan 30, 2024, 4:01 AM

                                @anabology yes same, thank you for helping me with the suggestions previously. I don’t really get them much anymore.

                                1 Reply Last reply Reply Quote 0
                                • B
                                  BioS
                                  last edited by Jan 30, 2024, 4:09 AM

                                  Serotonin blockers were used for migraine when nothing else was available. Methysergide was the best anti-migrane medication but it was withdrawn because it caused retroperitoneal fibrosis.

                                  In some countries, pizotifen and cyproheptadine are used for migraine prevention.

                                  Anything that lowers serotonin will prevent a migraine. GABA agonists like progesterone can also be used to abort an incoming one

                                  N 1 Reply Last reply Jan 30, 2024, 7:28 PM Reply Quote 0
                                  • R
                                    rayjeet
                                    last edited by Jan 30, 2024, 4:42 AM

                                    eat sugar

                                    1 Reply Last reply Reply Quote 0
                                    • H
                                      Hando-Jin @anabology
                                      last edited by Jan 30, 2024, 6:25 AM

                                      @anabology a big dose of t3 can stop a lot of bad things. I've gotten rid of extremely bad internal hemorrhoids using decent amounts of t3 for a few days. Worth it even though it causes fatigue.

                                      1 Reply Last reply Reply Quote 0
                                      • N
                                        normalgirl @Hando-Jin
                                        last edited by Jan 30, 2024, 7:20 PM

                                        @Hando-Jin I've confirmed it to not be an estrogen problem since they don't have any marked frequency around my menstrual cycle or with any hormone changes. I am currently taking tyronene which has helped some but hasn't completely gotten rid of them. There's more work to be done

                                        ~normalgirl*+•.’

                                        1 Reply Last reply Reply Quote 0
                                        • N
                                          normalgirl @Smitty
                                          last edited by Jan 30, 2024, 7:23 PM

                                          @Smitty Ironically they're resistant to aspirin, which is why I started getting concerned. For around 2 months they were happening almost every day

                                          ~normalgirl*+•.’

                                          1 Reply Last reply Reply Quote 0
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