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    Small amount of coconut oil orally increases wound healing

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    • cs3000C
      cs3000
      last edited by cs3000

      Interestingly it only took ~ a teaspoon of coconut fat a day
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714777/

      aeaeb310-cdc7-42bf-b61d-05c99d3d2024-image.png

      edit: maybe the fermentation process used in that allows for higher polyphenol count , but i doubt that plays a major role for such a small amount https://www.researchgate.net/figure/TPCs-in-coconut-oils-prepared-by-different-extraction-methods-expressed-as-gallic-acid_tbl1_363382404
      e.g gives catechin at ~1.2mg/100g which is fuck all at 5g

      Increased a VEGF receptor (helps new blood vessels grow faster and activates keratinocyte cell migration + helps them proliferate)
      and this receptor helps limit scar formation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080089/

      • The findings with the VEGF-E variants suggest that VEGFR-2 activation can promote healing of cutaneous wounds without the inflammatory side effects associated with VEGFR-1 or VEGFR-3 activation. The impact of VEGFR-2 activation on ST formation is, however, unknown. We therefore utilized the selectivity of VEGF-E to examine the role of VEGFR-2 in inflammation, fibrosis, vessel functionality, and the quality of skin repair using a murine full-thickness skin wound model. Purified VEGF-ENZ-2 protein was administered until the time of wound closure. Selective activation of VEGFR-2 with the VEGF-E variant significantly increased interleukin (IL)-10 expression, leading to decreased macrophage infiltration, myofibroblast differentiation, and ST formation, while improving capillary pericyte coverage and structure of the collagen matrix.

      • The findings from this study indicate that in the absence of VEGFR-1 binding, VEGFR-2 stimulation can enhance the quality of skin repair. Selective activation of VEGFR-2 may therefore be a therapeutic option for impaired healing or excess scarring.

      "world," as a source of new perceptions
      more https://substack.com/@cs3001

      "Self-organizing systems decay only if they have assimilated inertia and — with a little support of the right kind— the centers of degeneration can become centers of regeneration"

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