What 20th century experiment should I replicate?
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Hi all,
I'm currently a graduate student studying biostatistics. In Fall 2025, I'm going to have the opportunity to work with some other master's students to design a study.
What experiment from the 20th century should I try to replicate that will really expose contemporary scientific "knowledge" in biology?
The one I'm thinking of is randomizing mice to groups where the sum of PUFA + SFA + Sugar(or starch) is equal in calories for all groups but the ratios of PUFA, SFA, Sugar are varied across groups. I might even introduce an arm in which I see how high I can get the metabolic rate in the low PUFA groups by supplementing small amounts of liver.
I remember Peat reporting that the high PUFA groups were all fat whereas the low PUFA were all lean.
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You're already off to an excellent start. Consider putting each group through physical and mental trials to demonstrate the most exacerbating effects of each diet, too.. As an ancillary study.
