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    Urgently need studies on negative effects of "normal"(low-end) testosterone or positive effects of high testosterone

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    • J
      James
      last edited by

      Do you guys know of any studies on the negative effects of testosterone below 500ng/dL ? (Georgi said in the 1960s 500ng/dL was the low end of the normal range)

      Do you guys know of any studies on the positive effects of natural testosterone being high (over 800ng/dl) ?

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      • J
        James
        last edited by

        I do recall Georgi saying that some old endocrinological texts say that men with total Testosterone <500 cannot really father children naturally.

        but I couldn't find any studies so far

        @haidut

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        • M
          Mulloch94
          last edited by Mulloch94

          Uhhh yeah, just open up any Pudmed or Google Scholar and search "low testosterone" and pick your poison lol.

          Not sure about studies showing positive benefits from high T.

          But as for low T the journals are riddled with them. Everything from anxiety, low energy, sexual dysfunction, to more serious shit like insulin resistance and heart disease.

          Take this for an example: https://www.sciencedaily.com/releases/2010/10/101019212921.htm

          This one is for heart disease.

          "During the monitoring period almost twice as many men with low testosterone died as did those with normal levels. One in five (41) of those with low testosterone died, compared with one in eight (12%) of those with normal levels.

          The only factors that influenced this risk were heart failure (left ventricular dysfunction), treatment with aspirin or a high blood pressure drug (beta blocker) and low bio-T levels.

          A low bio-T level was an independent risk factor for premature death from all causes and from heart disease, after taking account of other influential factors, such as age, other underlying health problems, smoking and weight.

          Borderline levels of low total testosterone (15.1mmol/l) also increased the risk of an early death."

          I think 15.mmol/l converts to something like 500ng/dl. It's close anyways, somewhere between 400-500ng/dl.

          Platt also wrote a good book on bio-identical hormones as well. Testosterone is especially important for heart health as the heart is one of the most concentrated sources of T receptors in the body. And T is important for proper K and Ca channel flow.

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          • J
            James @Mulloch94
            last edited by

            @Mulloch94 Thank you

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