When people are hypothyroid they run high on adrenaline. Cortisol too but cortisol is more like a mediator of sorts, or a facilitator. Most of the unpleasant symptoms are related to adrenaline. Caffeine can also raise adrenaline. In someone who's already adrenaline dominant (due to hypothyroidism) caffeine may be problematic.

I recommend the following 1) con leche from now on. Coffee, with equal parts of milk (preferably whole milk), will always make the caffeine slightly more tolerable. For one milk has a little carbohydrate in it, but it also come with saturated fat, which will slow the absorption. 2) have some salty gelatinous soup. Oxtail soup is a good and classic choice for a peater. I in fact have it for dinner most nights of the week. The combination of gelatin and salt will powerfully lower adrenaline. 3) carrot salad and/or lots of cooked white mushrooms. Stimulating bowel transit and introducing antiseptic fibers to the intestine will reduce endotoxin which powerfully burns through the liver's glycogen holding abilities. More glycogen = steady stream of glucose = less free fatty acids and adrenaline. 4) Consider a liver "defatting" protocol. This can be expensive, but it will do wonders for your health if you actually need it. High dose K2 (>45mgs), glycine, TUDCA, and choline. Not to mention the caffeine helps too. I'd run it daily for about 60 days. 5) Supplemental progesterone can be an excellent tool to crush adrenaline when you're in a pinch or if you're about to sleep. Usually 12-14 drops of Progest-E will kill adrenaline in it's track. 6) Magnesium can be helpful against adrenaline, also just in general for hypothyroid people who lose it easily. Boiled leafy greens like kale is a good choice. 7) Last but not least, getting on thyroid replacement will modulate adrenaline back into a healthy range. But this can take a while, because finding the right dose of thyroid is tricky for a lot of people. It can also initially sensitize yourself to adrenaline even more, making the above suggestions all the more important.

Hey, I wanted to revisit this and ask you something because I started to think about it after I logged off and it kinda troubled me a little.

Did your doctor ONLY measure your TSH before coming to their conclusion of "hyperthyroidism?" Or did they also measure T4 and T3?

That doctor could possibly profoundly screw up their diagnosis if they didn't measure other serum thyroid markers. Because the TSH can also be low from the thyroid not responding correctly to hypothalamic signals.

It's a really dumb thing to do to be honest. But it's worth asking because I've had doctors measure literally only the TSH before as well. I think a lot of that has to do with the papers you fill out. I recommend people put they have family history of thyroid disorders or something, just so they watch it more closely. I guess if you don't mind spending the money, just get the tests done yourself.

I could see how someone with poor liver health might feel better by switching to pure dextrose rather than incorporating high amounts of fructose in the diet. But all that's really suggesting is they've fucked themselves up on high-fat low carb diets in the past. And it's really got nothing to do with an "intrinsically toxic" fructose molecule. I'm also not so sure you'd need to resort to dextrose powder. Safe starches are obviously available, and Mike Fave was even nice enough to list some fruits with a good even ratio of glucose to fructose, like oranges (although "muh A" crowd won't touch orange things). Apples might wreck someone due to their insanely high fructose:glucose ratio.

@Peatful I was reacting to what @insomniac said in the other thread. But I guess if Smith is shitting on carbs (dextrose/glucose) now that might be one reason. Charlie allegedly still promotes carbohydrate based diets. Whether or not that's because he actually believes they're healthy or because it just so happens his store sells glucose powder is a question worth pondering.

Interesting to hear Charlie has had a falling out with Smith. Didn't think this movement would fall apart this fast.

@VehmicJuryman It's a day early anyways, lol.

@Lothric Cholesterol, vitamin D, PTH, prolactin would be good. Pair those results with your TSH, temps, pulse, and bowel frequency to reach a more accurate determination.

I think Ray said somewhere around 0.4. But he also said TSH isn't a reliable metric to gauge thyroid or metabolism. At least not by itself. Ray's point was pituitary hormones (like TSH) are usually signs of stress and inflammation. In terms of hypo or hyper thyroidisms there's no right answer here. A multitude of variables is important to consider. What's your cholesterol? What's your bowel movements like? temps and pulse? estrogen and prolactin? Vitamin D and PTH? Even finely tuned parameters (Taurine/Glycine, DHEA/cortisol, NAD/NADH) like what Georgi discussed here would give you a more detailed analysis. Metabolism is more like painting a picture than checking off bulletpoints.

Someone who's hypERrthyroid will probably have low cholesterol, elevated estrogen, elevated testosterone, elevated prolactin, high DHEA/cortisol ratio, elevated pulse and temps, frequent bowel movements, etc.

@GreekDemiGod said in Thyroid Log:

Reduced my T4 dosage and already feeling a difference within less than 2 days. I woke up in a better mood and more fresh this morning.
It’s clear that all that T4 was partially converting to rT3.

Keep in mind selenium is very important for T4's conversion to T3. A relatively sterile small intestine is important too, as endotoxin blocks that conversion.

Danny had the opinion that people with poor liver function (likely from endotoxin) respond better to less T4. Like a 2:1 or even 1:1 ratio of T4 to T3. There's probably some truth to this.

But I get the impression a lot of people believe it's best to just role with those ratios forever, lol. Taking T3 and T4 in even ratios can be a get-by, but it's not really a permanent solution. It's best to fix whatever is wrong the liver. Which isn't so easy, and usually require rigorous experimentation with diet. Namely removing any and all problematic foods (grains, legumes, nightshades, FODMAPS, etc.). Even fruits with a really high fructose:glucose ratio can be problematic for some people.

@CrumblingCookie said in Lidocaine:

Beware that both lidocaine and procaine exert agonism at (peripheral) CRH receptors.

Also, they both significantly inhibit osteoblasts. Procaine does that right away and this is very relevant already after a week of use. I.e. teeth can suddenly become wobbly in the weeks afterwards. Lidocaine at first promotes them (50-70mg max?) but then also drastically inhibits beyond low doses.

I think 70mg is way too high. I don't know what Peat said was ideal but I feel a very potent effect on just 20mg. Probably also not something worth using in a long-term stack either, only sporadically when needed. Just my opinion. But it's a lot like naltrexone, except maybe worse, because naltrexone has conflicting reports about it's liver toxic effects. Lidocaine doesn't, and reports seem to agree pretty definitively it can be hepatotoxic when used in high dosages or over long periods.