Topics created by Mulloch94

@Mulloch94 said in levated TSH is an independent risk factor for Major Depressive Disorder and Metabolic Syndrome.:

Good to know, thank you!

A propos

Newly released review this May. What's interesting here is many doctors won't consider someone for thyroid therapy unless their TSH is >5.0 mIU/L. So you're pretty much on your own if you're so called "subclinically" hypothyroid.

98453e8e-057c-43b9-9fe7-59d867fc5948-image.png

@evan-hinkle said in Doxycycline has antidepressant effects by lowering nitric oxide in mice:

@Mulloch94 thanks for posting this. I’m curious as to whether or not the benefit came from blocking or eliminating the endotoxin the mice were injected with, or if doxy itself lowered the iNOS that was upregulated due to the endotoxin?

Haidut had an old post talking about endotoxin being a typical cause of back pain. I’ve had unexplained back pain for a few years now that hits every morning but goes away as the day progresses. I assume it’s endotoxin related as I’ve had endotoxin issues in the past. I have used doxy, but never at the dose suggested here, (HED would be about 4mg/kg I believe). May give this a shot.

Thanks!

No problem! I'm sure there's some synergy between lowering the endotoxin and blocking nitric oxide. But if I had to guess, at least according to this study, the main mechanism is behind the nitric oxide suppressing effects. Because when they administered sodium nitroprusside the antidepressant action of doxy was inhibited.

@Jakeandpace Probably, or maybe they just remove problematic foods from their diet. Big thing about "peaters" (I've never liked that word, lol) is the dairy/milk. There's a shit ton of people that don't tolerate milk, so when they remove it they feel better. That doesn't mean vitamin A is bad, or calcium, or lactose, or whatever else they can think of. It means they continued to try and force a food that wasn't agreeing with them due to some misconception that a "way of life" (in this case peating) necessitates that they do so.

@Mulloch94 Bookmarking this post

@Mulloch94 Yeah, the corporate and "rational" (reductionistic) world is probably still in love with a single metric/KPI...

I guess that IQ may be somewhat helpful in measuring the ability to "connect the dots", but intelligence is also about perceiving things "out of the box" (predictive processing), knowing how to make sense of things, not being blinded by ego, etc.

There are also theories about extended cognition i.e. 4E

Fun fact, according to a test done many years ago when I was low in T3, my results in categories of IQ and "processing speed" were exactly on the opposite sides of the Gauss curve, LOL!

@Kilgore Yeah the coconut oil is good for frying. No taste imparted by the product.

This guy's content is great 🤣

Air mattress. Probably less work than a body bag. Comes with an intake valve too.

@Kilgore It was at that percise moment he realized he fucked up lmao. As hard as it may sound, I don't even know if the oil chug ranks at the top. Maybe it does, but the one where he eats a fucking cactus might just be worse, lol.

@BioEclectic Chris is pretty cool, I can't say I agree with everything he says, but I can't really say that about anyone so it's all good. The guy does relentless research, so I know he's never going into something half-cocked.

You could save your eggshells and just use a coffee grinder on them, rather then spending money on calcium carbonate. It's essentially the same thing.

Yeah that shit sucks about supermarket meats. Before I relocated I was getting most of my meats from a local source, but right now I'm not in contact with any good local guys to source product so I'm just keeping my meat consumption to a minimum.

I usually eat meat and veggies with dinner, but for breakfast and lunch it's been oatbran with casein protein (also a good source of calcium) and coffee with milk. I cook my oatbran in apple juice too.

@Truth Thankyou!