Fenclonine
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Has anybody tried fenclonine? I'm itching to see what zero serotonin feels like. There appear to be at least these three sources:
https://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=61111 cheapest
https://www.tcichemicals.com/US/en/p/C0253 more expensive but higher purity
https://www.sigmaaldrich.com/US/en/product/sigma/c6506 really expensive
On RPF there is a similar thread but only a couple people took the plunge and felt weird:
https://www.lowtoxinforum.com/threads/affordable-source-of-pcpa-fenclonine.3099/
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@engineer Why not just take a dopamine agonist/reuptake inhibitor
such as:
Cabergoline
Bromocriptine
Pramipexole (more extreme from my understanding)
Selegiline (probably the best option) -
@jamezb46 said in Fenclonine:
Cabergoline
Risk of valvular damage
Bromocriptine
Same
Pramipexole (more extreme from my understanding)
"Newer dopaminergic drugs like pramipexole have not been studied enough, even though they seem OK for now. I agree with Peat's principle to not trust drugs that have not been in the market for at least 20 years. Clinical trials are nothing more than a sharade proving merely that a drug won't kill too many people in too short of a time." - Haidut
Selegiline (probably the best option)
This one could work, but where perhaps can I procure such a substance?
I already have lisuride but it's pretty expensive and only a partial serotonin antagonist. The main reason I wanted to smash serotonin was this:
pCPA was used extensively in the 60s and 70s especially by US military scientist for some unique and I'd say bizarre experiments. It was used as a drug to induce "gay" behavior in humans, but they found out that it simply increased libido dramatically, where in the rats it made them lose preference for sexual partners and made them mount even...cats! So, it's not like the rats became gay, they just lost all fear and dedicated themselves to sexual "exploration" (even with cats), which, as you know from reading Peat, is a hallmark of health.
With such ridonkulicious results, I just have to try a replication study.
Update: Upon doing a little more research, it appears as though fenclonine doesn't work very well in humans, but there isn't much data available.
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https://mexipharm.net/categories/Depression/Emsam
I think phenylpiracetam could also be useful, but if you use it you probably need to look into sleep optimization because some people claim that it induces insomnia.
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@jamezb46 I just ordered some pramipexole because it appears as though it is in fact Peaty (it's been 29 years and there are no signs of effects other than those from dopamine agonism).
Let's see what happens!
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Wow! These articles are walking advertisements for the efficacy of pramipexole:
https://www.bbc.com/news/articles/cpqnpryxvrro
James's case is one of 50 the BBC has now been contacted about, the majority concerning men being treated for movement disorders whose behaviour changed dramatically after being prescribed medication from a specific family of drugs.
Often, behaviour changed after many years of taking the medicines at increasing doses, the men told us.
In March, we revealed how women had not been warned by doctors that taking the same type of medication for restless leg syndrome (RLS) could cause them to cruise for sex and gamble compulsively - placing them at personal risk and ruining their finances, careers and relationships.
https://theamericanscholar.org/the-degradation-drug/
It started with selfies. Hannah had never taken a selfie before, or even given the idea much thought. She was a tenured 39-year-old psychology professor at a New England college. But eight days after she started on pramipexole, a drug prescribed off-label by her psychiatrist for depression and anxiety, Hannah began taking photos of herself obsessively. She couldn’t explain the desire. At the time, it didn’t even seem especially strange.
Neither did the hats. She just felt like wearing them—or, really, any item that would cover her head. A gray wig. A red fedora. A spider-webbed fascinator. A vintage, canary-yellow beehive cap. Ordinarily Hannah was a modest dresser. But within weeks, she began ordering exotic clothing online, including flamboyant suits made for adolescent boys. “I had green velvet, red velvet, black velvet,” Hannah told me when we discussed her case. “I had my tuxedo. I had my plaids.” (To protect Hannah’s privacy, I have changed her name and some of the identifying details of her story.) Many of these outfits were impulse purchases. “Sometimes I could drop a grand in less than 30 minutes, waking up in the middle of the night to shop,” she said. One selfie from this period shows her wearing headphones, a short strapless dress, and a Batman mask. Men began to pay her a lot of attention. “I didn’t think to stop and analyze too much what was happening,” she said. “It was a constant rock ’n’ roll party in my head, and I was the star.”
Us Peaters will almost certainly be in better shape.
Edit: Another one!
https://www.bbc.com/news/articles/clym0g4rlr2o
Edit 2: it just doesn't stop coming in
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@engineer safegenericpharmacy in india sells it
