Low soluble fiber = leaky gut?
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research indicates that when gut bacteria are starved of dietary fiber, they can begin to consume the protective mucus lining of the intestines. This mucus layer is a critical barrier, and its erosion can lead to increased inflammation and susceptibility to infection.
This seems to apply to soluble fiber -
@user73636 said in Low soluble fiber = leaky gut?:
research indicates that when gut bacteria are starved of dietary fiber, they can begin to consume the protective mucus lining of the intestines.
=> Need a context and a study.
Yes, this is accurate and refers to a well-known, seminal study on gut microbiome health.
=> A combination of host genetic susceptibility, low dietary fiber and intestinal bacteria exacerbate colitis.
doi: 10.21203/rs.3.rs-2518251/v1 2023 Mar 13.
Context: The "If You Don't Feed Them, They Eat You" Mechanism
• The Problem: The mucus lining (largely composed of MUC2 glycoproteins) protects the intestinal epithelial cells from being directly attacked by bacteria.
• The Mechanism: When gut bacteria are deprived of dietary fiber (their preferred food source), they turn to the next best source of nutrients: the carbohydrates in the protective colonic mucus layer.
• The Result: This erosion of the mucus layer makes the intestinal lining thinner and significantly more vulnerable to inflammatory pathogens.
• Significance: This finding provides a direct mechanism for why low-fiber, high-fat "Western diets" are associated with increased risk of ulcerative colitis, Inflammatory Bowel Disease (IBD), and metabolic disorders.
Key Study
"A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility"
Authors: Desai et al. (Lead researchers include Eric Martens at the University of Michigan and Mahesh Desai).
Journal: Cell (Nov 17, 2016).
Comment (LucH): Not only when deprived but when some phyla take the lead.
When you decide to correct and tend towards 30 g (1 oz.) fiber, you need to begin progressively and adapt yourself to transit. We need 4 colors to optimize the different effects.
