Vitiligo
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What does Ray Peat have to say about vitiligo? Can it be associated with any deficiencies at all? Any possible treatments or ways to stop further progression?
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“Vitamin D and progesterone favor the survival of pigment cells.” Ray Peat Email Depository RPF
"Cell movements in solid tissues aren't limited to the short distances between capillaries and the tissues nourished by those capillaries, rather, cells can migrate much greater distances, without entering the bloodstream. The speed of a single cell moving by ameboid motion can be measured by watching cells on a glass slide as they move toward food, or by watching cells of the slime mold Dictyostelium when they are aggregating, or by watching the pigment cells in and around moles or melanomas, under the influence of hormones. At body temperature, a single cell can crawl about an inch per day. Waves or spots of brown pigment can be seen migrating through the skin away from a mole, preceding the disintegration of the mole under the influence of progesterone or DHEA. Under ordinary conditions, pigment cells can sometimes be seen migrating into depigmented areas of skin, during the recovery of an area affected by vitiligo. These organized movements of masses of cells happen to be easy to see, but there is evidence that other types of cell can reconstruct tissues by their ameboid movements, when circumstances are right. Tumors or tissue abnormalities can appear or disappear with a suddenness that seems impossible to people who have studied only fixed tissue preparations..........................
The regulation of cell renewal probably involves all of the processes of life, but there are a few simple, interacting factors that suppress renewal. The accumulation of polyunsaturated fats, interacting with a high concentration of oxygen, damages mitochondria, and causes a chronic excessive exposure to cortisol. With mitochondrial damage, cells are unable to produce the progesterone needed to oppose cortisol and to protect cells.
Choosing the right foods, the right atmosphere, the right mental and physical activities, and finding the optimal rhythms of light, darkness, and activity, can begin to alter the streaming renewal of cells in all the organs. Designing a more perfect environment is going to be much simpler than the schemes of the genetic engineers." Ray Peat
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