Boron.
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I do not think Dr. Peat spoke very highly of boron, but I have found it useful to experiment with. Borax is a good way to do that and it’s super safe and super cheap.
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Ray about boron "Plants need it. I don't think people should have any more of it than they get from foods."
Haidut about it:
"Boron is HIGHLY estrogenic. The bodybuilding community was crazy about it in the 1990s, but then they found out firsthand that it raises estrogen (I think all 3 types) and dumped it. Boron has similar effects to cadmium, nickel, cobalt, etc and they are all estrogenic and carcinogenic in higher doses.
Peat is right that unless you are deficient you'd better not mess with it. See below for a study in men.http://link.springer.com/article/10.1007%2FBF02785299
"...Supplementation with 10 mg B/d for 4 wk resulted in 84% of the supplemented dose being recovered in the urine. Plasma estradiol concentrations increased significantly as a result of supplementation (51.9±21.4 to 73.9±22.2 pmol/L;p<0.004) and there was a trend for plasma testosterone levels to be increased. However, there was no difference in plasma lipids or the oxidizability of low-density lipoprotein Our studies suggest that the absorption efficiency of B is very high, and estimation of the urinary B concentration may provide a useful reflection of B intake. In addition, the elevation of endogenous estrogen as a result of supplementation suggests a protective role for B in atherosclerosis.""
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BTW Nothing Boring About Boron -
@Kvirion it is not highly estrogenic. But, I don't think it is terribly useful to take as a nutrient unless you have arthritis. It is not good as a way to raise testosterone. But it is fairly harmless to experiment with if you aren't using too much.
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@Ecstatic_Hamster Yep, moderation is a key.
BTW, I would like to know the current opinion of @haidut about its estrogenicity.
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@Kvirion it is probably estrogenic for sure. But it also raises testosterone.
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@bolditinerary this article might interest you:
"As the current article shows, boron has been proven to be an important trace mineral because it (1) is essential for the growth and maintenance of bone; (2) greatly improves wound healing; (3) beneficially impacts the body's use of estrogen, testosterone, and vitamin D; (4) boosts magnesium absorption; (5) reduces levels of inflammatory biomarkers, such as high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor α (TNF-α); (6) raises levels of antioxidant enzymes, such as superoxide dismutase (SOD), catalase, and glutathione peroxidase; (7) protects against pesticide-induced oxidative stress and heavy-metal toxicity; (8) improves the brains electrical activity, cognitive performance, and short-term memory for elders; (9) influences the formation and activity of key biomolecules, such as S-adenosyl methionine (SAM-e) and nicotinamide adenine dinucleotide (NAD(+)); (10) has demonstrated preventive and therapeutic effects in a number of cancers, such as prostate, cervical, and lung cancers, and multiple and non-Hodgkin's lymphoma; and (11) may help ameliorate the adverse effects of traditional chemotherapeutic agents."
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Walter Last writes that a boron deficiency is the cause of arthritis.
https://yummy.doctor/wp-content/uploads/2021/04/Borax-conspiracy.pdf
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@Ecstatic_Hamster I have used borax as pain relief for osteoarthritis, had no idea it was borate of sodium, I found it on holistic medicine website I don't remember the name. Do you think it should be used topically?
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@Kvirion Thank you for the information, however at what dose does it have that estrogenic effect? I was planning to supplement 1mg or 3 mg boron/day?
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@Ecstatic_Hamster Yeah, boron increases free T, that and bone health is what I was aiming for.
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@Ecstatic_Hamster how much do you think is too much? And if you have experimented with it, I'd like to know how you went about it in detail, if you don't mind. Thank you.
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@Uroš Thank you for this resource, that's a nice list of benefits it could provide, especially wound healing, I have diabetes and my wounds take forever to heal.
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@otto Interesting, because I suspect I have osteoarthritis, my joints are creaky and they grind against each other. A combo of D3 and calcium has been improving the symptoms a bit.
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@bolditinerary said in Boron.:
Thank you for the information, however at what dose does it have that estrogenic effect? I was planning to supplement 1mg or 3 mg boron/day?
1 mg should be a safe bet...
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@Kvirion okay thank you.
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@bolditinerary I myself regulary consume boron (3 mg) + collagen for my OA knee.
This article might be of help: Essentiality of boron for healthy bones and joints
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@Uroš Thank you very much. I'm currently taking 1mg and seeing pain subside, especially at night time, I'll increase the dosages and see what happens.