Thoughts about DHT
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For some DHT is a trash hormone after puberty, for others it is absolutely vital, why not both? Like if you can't digest milk, it might be the milk or your gut, maybe if your body can't handle DHT, it means that there is a unknown process that makes you intolerant to DHT. So inhibiting it might make you healthier in some cases, fuck you up in others. I know that when I took it, the scalp inflammation and the pains that I felt for almost 2 decades disappeared in less than two weeks, i cannot disregard this reality, and I also cannot disregard the bad experiences about it. What do you think?
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Do balding people have higher amounts of DHT in the body/scalp compared to non-baldies or is their bodies just worse at handling it?
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"Increased serum concentrations of DHT were observed in patients with androgenetic alopecia (17 women, 5 men), but also in the control group. The differences in mean values of DHT were not significant according to the types of alopecia and the control group. Increased serum concentrations of DHT were not correlated with the advance of alopecia."
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@voldtzeig said in Thoughts about DHT:
Do balding people have higher amounts of DHT in the body/scalp compared to non-baldies or is their bodies just worse at handling it?
I think it might be the latter, difficult to compare DHT levels, a non-baldie can rock supra-level of DHT compared to a baldie, we're all unique organisms. There are even popular health-influencers on X promoting increasing DHT, with excellent reasons, and they still rock their hair.
I still think you can induce baldness with DHT, because DHT is associated with the culprit while not being the culprit itself.
Finasteride is maybe truly a medicine for some, and a poison for others.
Anyway, just my thoughts, with zero medical knowledge of course. -
MPB reminds me of PCOS, where blocking androgens is somehow helpful, but I doubt DHT is central to MPB. Insulin resistance seems to be central to PCOS and may be to MPB as well.
It happens that lowering DHT helps MPB, but it may be by a very long indirect chain of cause-effects.
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"Similar hormonal, metabolic, and clinical alterations occurring in PCOS women have also been reported in their male relatives, suggesting a association between the male and female forms of the syndrome. Although the remarkable clinical manifestation of the male equivalent PCOS is diagnosed by the early-onset androgenetic alopecia, characterized by hair recession, pronounced hypertrichosis, insulin resistance, biochemical and hormonal abnormalities, the hormonal/metabolic profile is still controversial."
Yeah, I read that there :[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382675/], had the same conclusions. Prostate enlargement may be linked with hairloss and baldness in males. Interestingly for women even if they don't have a prostate, the "equivalent" the Skene's glands are larger than normal in thoses with polycystic ovarian syndrome (PCOS).
AGA might be just male PCOS after all.
