Why is Thiamine (HCL) Hyperthermic
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Whenever I take high-dose Thiamine HCL, I seem to enter a stressful hyperthermic state. I get a big rise in adrenaline, body temperature (often in excess of 37.2), excess sweating, shaking, and require a ridiculous amount of salt to prevent constant peeing. Is this due to too much CO2? Lowering of Serotonin?
My best guess is the former, as I should be raising CO2 beyond what would normally be in my system, thus, raising adrenaline.
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@Master Update. Salt was the wrong way to go. Started getting bad heart palpitations and had to drink some orange juice to relieve. My guess is a magnesium deficiency. Either way, seems to create electrolyte imbalances in me in high doses.
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@Master magnesium and potassium is important with high b-vitamins.
Since adding a 1:1 ratio of tmg to my b3 for example i do not experience much of any sideeffect from b vitamins anymore which used to be this internal stress response where i would have energy but feel at unease and agitated. Nervous energy so to speak.
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Hi,
It's advised to begin slowly with thiamin.
Several processes are stimulated.
The brain is going to try to adapt the stimulus response, with more or less success (adaption time needed).
Wait before doing it again.
Take now magnésium bisglycinate (one scope = 2-3 gr) and potassium citrate powder (one scope 2 ml = 1.3 gr K).
And do it again with maximum 50 mg thiamin HCL (cut the gel into 2 pieces). With a meal.
NB: Too much HCL is toxic. Adapt the posology to needs.
I can give you a link if you want to go deeper in the comprehension of the mechanism.
Or go and watch Overton's videos. -
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Probably just a rise in metabolism. Same thing can happen when taking thyroid, however you eventually adjust to the effects of thyroid. Not sure about "high-dose" thiamine. Thiamine as opposed to thyroid will carry the additional risk of lower potassium levels.
In regards to the adrenaline issue just eat more carbs and salt. If that doesn't cut it you could try also adding taurine, niacinamide, inosine, or progesterone. Basically anything that will blunt adrenaline until your metabolic "set-points" adjust to the new normal.
