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how to turn lysergic acid into lysergic acid diethylamide?

The Junkyard
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  • R
    rudolf_steiner
    last edited by Aug 3, 2024, 4:55 AM

    Does anyone have any lit on turning lysergic acid into lysergic acid diethylamide? I'm growing ergot and will turn it into ergotamine tartrate following the 1918 arthur stoll patent method and I have the equipment/knowledge to hydrolyze it into pure lysergic acid. I have no idea what to do next and it looks like I have to relearn some organic chemistry. I probably won't trust anything anyone posts here anyway but also some direction or reference texts would be helpful maewan heads thanks

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      psi
      last edited by Aug 15, 2024, 2:29 AM

      Couple it with diethylamine using a catalyst like (2-(Thiophen-2-ylmethyl)phenyl)boronic acid in this example DOI: 10.1021/acs.joc.5b00378

      You will fail to isolate sufficient quantities and give up quickly. Or you'll fail to acquire diethylamine.

      Why bother with it anyway if there's the primary amide that can be isolated from plants? Better yet why bother with so called psychedelics. Only spiritfaggots take them and convince themselves the effects are good.

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