Mushrooms - Trehalose
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Really enjoyed this article by Dr. Peat: https://wiki.chadnet.org/files/mushrooms-observations-and-interpretations.pdf
Mostly interested in this specific excerpt from it, regarding Trehalose, the sugar in mushrooms, and what it can do. Has anyone supplemented Trehalose to address any of these degenerative diseases, or do any of you know of any studies specifically on this? Any thoughts appreciated."The stable cell substance is more lipophilic
than ordinary water, making fats less likely to
separate into droplets inside the cell, and regulating the interactions of proteins, including prevention or their clumping. In degenerative diseases,
the clumping of proteins (for example, prion, tau,
amyloid, lens crystallin, synuclein, polyglutamine)
is an important aspect of cell failure. This impairment of the cell's solvent properties results from
an energy source that doesn't fully compensate for
stress (a process that leads to excitotoxicity), but
simply adding a stabilizing substance such as
trehalose can maintain the proper solvation of
proteins." -
@JaredPitts - Dr. Peat's newsletter was published almost 10 years ago. Here is link to a Danny Roddy video in which Dr. Peat mentions trehalose.
1:01:14 - The mushroom sugar, trehaloseTherapeutic potential of trehalose
in neurodegenerative diseases: the
knowns and unknowns (2025)
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@DavidPS - Awesome. Very much appreciate the resources.
